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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 14, Iss. 18 — Sep. 4, 2006
  • pp: 8103–8110

Implementation of a fast method for high resolution phase contrast tomography

A. Groso, R. Abela, and M. Stampanoni  »View Author Affiliations

Optics Express, Vol. 14, Issue 18, pp. 8103-8110 (2006)

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We report the implementation of a method which can yield the 3D distribution of the phase (refractive index) of a weakly absorbing object from a single tomographic data set. In order to reduce the residual absorption artifact (due to the fact that only one data set is used) the original algorithm presented by A. V. Bronnikov is amended by adding in the filter a factor found by using a semi empirical approach. The quality of the reconstruction is largely sufficient for optimal segmentation and further postprocessing even though the filter correction is based on assumption of constant absorption. This one step approach allows keeping radiation dose to the minimum. Spatial resolution is comparable to the conventional absorption based technique. The performance of the method is validated by using an established phase contrast technique.

© 2006 Optical Society of America

OCIS Codes
(100.5070) Image processing : Phase retrieval
(170.6960) Medical optics and biotechnology : Tomography
(340.7440) X-ray optics : X-ray imaging

ToC Category:
Image Processing

Original Manuscript: June 20, 2006
Revised Manuscript: August 21, 2006
Manuscript Accepted: August 23, 2006
Published: September 1, 2006

Virtual Issues
Vol. 1, Iss. 10 Virtual Journal for Biomedical Optics

A. Groso, R. Abela, and M. Stampanoni, "Implementation of a fast method for high resolution phase contrast tomography," Opt. Express 14, 8103-8110 (2006)

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