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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 15, Iss. 16 — Aug. 6, 2007
  • pp: 10390–10396

In vivo three-dimensional microelectromechanical endoscopic swept source optical coherence tomography

Jianping Su, Jun Zhang, Linfeng Yu, and Zhongping Chen  »View Author Affiliations


Optics Express, Vol. 15, Issue 16, pp. 10390-10396 (2007)
http://dx.doi.org/10.1364/OE.15.010390


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Abstract

In clinical applications, three-dimensional (3-D) microscopic image volume reveals tissue morphological changes, which are closely related to pre-cancer and early stage disease, much better than two-dimensional images. However, the traditional endoscope only achieves two-dimensional surface images. In this paper, a 3-D endoscopic microscope was developed based on a rotational microelectromechanical system (MEMS) probe [1]. The 3-D helix scan mode was realized by combining a MEMS motor rotational scan and linear stage transversal movement. In order to coordinate the high spin speed of MEMS motor inside the endoscope, an optical coherence tomography (OCT) system with a broadband fast swept laser was used. In vivo 3-D image volumes of rabbit esophagus and trachea were demonstrated.

© 2007 Optical Society of America

OCIS Codes
(000.2170) General : Equipment and techniques
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: June 4, 2007
Revised Manuscript: July 23, 2007
Manuscript Accepted: July 26, 2007
Published: August 2, 2007

Virtual Issues
Vol. 2, Iss. 9 Virtual Journal for Biomedical Optics

Citation
Jianping Su, Jun Zhang, Linfeng Yu, and Zhongping Chen, "In vivo three-dimensional microelectromechanical endoscopic swept source optical coherence tomography," Opt. Express 15, 10390-10396 (2007)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-16-10390


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References

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