Spectral-domain spectrally-encoded endoscopy
Optics Express, Vol. 15, Issue 5, pp. 2432-2444 (2007)
http://dx.doi.org/10.1364/OE.15.002432
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Abstract
Spectrally-encoded miniature endoscopy uses a single optical fiber and wavelength division multiplexing to obtain macroscopic images through miniature, flexible probes. In turn, it has the potential to enable two- and three-dimensional imaging within the body at locations that are currently difficult to access with conventional endoscopes. Here we present a novel detection scheme for spectrally-encoded endoscopy using spectral-domain interferometry. Compared to previous time-domain configurations, this new detection method results in greater than 1000-fold increase in sensitivity (77 dB), a 6-fold increase in imaging speed (30 volumes per second), and a 2-fold increase in depth range (2.8 mm). We demonstrate spectrally-encoded, spectral-domain detection by conducting video-rate, three-dimensional imaging in a variety of specimens, including the paws of a mouse embryo and excised human ear bones. Our results show that this new technology enables video rate spectrally-encoded endoscopy and will therefore be useful for a variety of minimally invasive medical applications.
© 2007 Optical Society of America
OCIS Codes
(110.1650) Imaging systems : Coherence imaging
(170.2150) Medical optics and biotechnology : Endoscopic imaging
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(170.6900) Medical optics and biotechnology : Three-dimensional microscopy
ToC Category:
Medical Optics and Biotechnology
History
Original Manuscript: December 4, 2006
Revised Manuscript: January 12, 2007
Manuscript Accepted: January 17, 2007
Published: March 5, 2007
Virtual Issues
Vol. 2, Iss. 4 Virtual Journal for Biomedical Optics
Citation
Dvir Yelin, W. M. White, Jason T. Motz, Seok H. Yun, Brett E. Bouma, and Guillermo J. Tearney, "Spectral-domain spectrally-encoded endoscopy," Opt. Express 15, 2432-2444 (2007)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-5-2432
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