OSA's Digital Library

Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 15, Iss. 8 — Apr. 16, 2007
  • pp: 4848–4856

Fiber laser-based light source for coherent anti-Stokes Raman scattering microspectroscopy

Esben Ravn Andresen, Carsten Krogh Nielsen, Jan Thøgersen, and Søren Rud Keiding  »View Author Affiliations


Optics Express, Vol. 15, Issue 8, pp. 4848-4856 (2007)
http://dx.doi.org/10.1364/OE.15.004848


View Full Text Article

Enhanced HTML    Acrobat PDF (235 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

We demonstrate an alternative light source for CARS microspectroscopy based on a fiber laser and a photonic-crystal fiber. The light source simultaneously delivers a near-transform-limited picosecond pump pulse at 1033.5 nm and a frequency-shifted, near-transform-limited femtosecond Stokes pulse, tunable from 1033.5 nm to 1400 nm. This corresponds to a range 0 - 2500 cm-1, so that Raman-active vibrations in this frequency range can be probed. The spectral resolution is 5 cm-1, given by the spectral width of the pump pulse. The frequency range that can be probed simultaneously is 200 cm-1-wide, given by the spectral width of the Stokes pulse. The achievable average powers are 50 mW for the pump and 2 mW for the Stokes pulse. The repetition rate is 35 MHz. We demonstrate the capability of this light source by performing CARS microspectroscopy and comparing CARS spectra with Raman spectra.

© 2007 Optical Society of America

OCIS Codes
(140.3510) Lasers and laser optics : Lasers, fiber
(180.5810) Microscopy : Scanning microscopy
(300.6230) Spectroscopy : Spectroscopy, coherent anti-Stokes Raman scattering

ToC Category:
Lasers and Laser Optics

History
Original Manuscript: February 27, 2007
Revised Manuscript: March 30, 2007
Manuscript Accepted: April 3, 2007
Published: April 6, 2007

Virtual Issues
Vol. 2, Iss. 5 Virtual Journal for Biomedical Optics

Citation
Esben R. Andresen, Carsten K. Nielsen, Jan Thøgersen, and Søren R. Keiding, "Fiber laser-based light source for coherent anti-Stokes Raman scattering microspectroscopy," Opt. Express 15, 4848-4856 (2007)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-8-4848


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. A. Zumbusch, G. R. Holtom, and X. S. Xie, "Three-dimensional vibrational imaging by Coherent Anti-Stokes Raman Scattering," Phys. Rev. Lett. 82, 4142-4145 (1999). [CrossRef]
  2. E. O. Potma, D. J. Jones, J.-X. Cheng, X. S. Xie, and J. Ye, "High-sensitivity coherent anti-Stokes Raman scattering microscopy with two tightly synchronized picosecond lasers," Opt. Lett. 27, 1168-1170 (2002). [CrossRef]
  3. M. Müller and J. M. Schins, "Imaging the thermodynamic state of Lipid membranes with Multiplex CARS Microscopy," J. Phys. Chem. B 106, 3715-3723 (2002). [CrossRef]
  4. J.-X. Cheng and X. S. Xie, "Coherent anti-stokes Raman Scattering Microscopy: Instrumentation, Theory, and Applications," J. Phys. Chem. 108, 827-840 (2004). [CrossRef]
  5. F. Ganikhanov, S. Carrasco, X. S. Xie, M. Katz, W. Seitz, and D. Kopf, "Broadly tunable dual-wavelength light source for coherent anti-Stokes Raman scattering microscopy," Opt. Lett. 31, 1292-1294 (2006). [CrossRef] [PubMed]
  6. T. Hellerer, A. M. K. Enejder, and A. Zumbusch, Appl. Phys. Lett. 85, 25-27 (2004). [CrossRef]
  7. N. Dudovich, D. Oron, and Y. Silberberg, "Single-pulse coherently controlled nonlinear Raman spectroscopy and microscopy," Nature 418, 512-514 (2002). [CrossRef] [PubMed]
  8. H. N. Paulsen, K. M. Hilligsøe, J. Thøgersen, S R Keiding, and J. J. Larsen, "Coherent anti-Stokes Raman scattering microscopy with a photonic crystal fiber based light source," Opt. Lett. 28, 1123-1125 (2003). [CrossRef] [PubMed]
  9. T. W. Kee and M. T. Cicerone, "Simple approach to one-laser, broadband coherent anti-Stokes Raman scattering microscopy," Opt. Lett. 29, 2701-2703 (2004). [CrossRef] [PubMed]
  10. H. Lim, J. Buckley, A. Chong, and F. W. Wise, "Fibre-based source of femtosecond pulses tunable from 1.0 to 1.3 μm," Electron. Lett. 40, 1523-1525 (2004). [CrossRef]
  11. J. Takayanagi, T. Sugiura, M. Yoshida, and N. Nishizawa, "1.0-1.7- μm wavelength-tunable ultrashort-pulse generation using Femtosecond Yb-Doped Fiber Laser and Photonic Crystal Fiber," IEEE Photon. Technol. Lett. 18, 2284-2286 (2006). [CrossRef]
  12. R. Herda and O. G. Okhotnikov, "Dispersion compensation-free fiber laser mode-locked and stabilized by highcontrast saturable absorber mirror," IEEE J. Quantum Electron. 40, 893-899 (2004). [CrossRef]
  13. T. Schreiber, T. V. Andersen, D. Schimpf, J. Limpert, and A. Tünnermann, "Supercontinuum generation by femtosecond single and dual wavelength pumping in photonic crystal fibers with two zero dispersion wavelengths," Opt. Express 13, 9556-9569 (2005). [CrossRef] [PubMed]
  14. F. M. Mitschke and L. F. Mollenauer, "Discovery of the soliton self-frequency shift," Opt. Lett. 11, 659-661 (1986). [CrossRef] [PubMed]
  15. J. P. Gordon, "Theory of the soliton self-frequency shift," Opt. Lett. 11, 662-664 (1986). [CrossRef] [PubMed]
  16. M. D. Levenson and S. S. Kano, Introduction to nonlinear laser spectroscopy (Academic Press, inc. 1987).
  17. L. A. Gomes, L. Orsila, T. Jouhti, and O. G. Okhotnikov, "Picosecond SESAM-Based Ytterbium Mode-Locked Fiber Lasers," IEEE J. Quantum Electron. 10, 129-136 (2004). [CrossRef]
  18. J. Limpert, N. Deguil-Robin, I. Manek-Hönninger, F. Salin, T. Schreiber, A. Liem, F. Röser, H. Zellmer, A. T nnerman, A. Courjaud, C. Hönninger, and E. Mottay, "High-power picosecond fiber amplifier based on nonlinear spectral compression," Opt. Lett. 30, 714-716 (2005). [CrossRef] [PubMed]
  19. D. G. Ouzounov, F. R. Ahmad, D. Müller, N. Venkataraman, J. Silcox, K.W. Koch, and A. L. Gaeta, "Generation of Megawatt Optical Solitons in Hollow-Core Photonic Band-Gap Fibers," Science 301, 1702-1704 (2003). [CrossRef] [PubMed]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited