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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 16, Iss. 17 — Aug. 18, 2008
  • pp: 12746–12756

In vivo measurement of erythrocyte velocity and retinal blood flow using adaptive optics scanning laser ophthalmoscopy

Zhangyi Zhong, Benno L. Petrig, Xiaofeng Qi, and Stephen A. Burns  »View Author Affiliations


Optics Express, Vol. 16, Issue 17, pp. 12746-12756 (2008)
http://dx.doi.org/10.1364/OE.16.012746


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Abstract

In vivo measurement of retinal blood flow is obtained by measuring the blood velocity of erythrocytes and lumen diameters of the blood vessels using an adaptive optics scanning laser ophthalmoscope. Erythrocyte velocity is measured by tracking erythrocytes moving across a horizontal scanning line. This approach provides high temporal bandwidth measurements, allowing the fluctuation of blood flow during cardiac cycles to be measured. The technique is most applicable to medium-sized blood vessels.

© 2008 Optical Society of America

OCIS Codes
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(330.4300) Vision, color, and visual optics : Vision system - noninvasive assessment
(110.1080) Imaging systems : Active or adaptive optics

ToC Category:
Vision, color, and visual optics

History
Original Manuscript: May 27, 2008
Revised Manuscript: July 11, 2008
Manuscript Accepted: July 16, 2008
Published: August 7, 2008

Virtual Issues
Vol. 3, Iss. 10 Virtual Journal for Biomedical Optics

Citation
Zhangyi Zhong, Benno L. Petrig, Xiaofeng Qi, and Stephen A. Burns, "In vivo measurement of erythrocyte velocity and retinal blood flow using adaptive optics scanning laser ophthalmoscopy," Opt. Express 16, 12746-12756 (2008)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-16-17-12746


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