Quantitative optical tomography of sub-surface heterogeneities using spatially modulated structured light
Optics Express, Vol. 17, Issue 17, pp. 14780-14790 (2009)
http://dx.doi.org/10.1364/OE.17.014780
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Abstract
We present a wide-field method for obtaining three-dimensional images of turbid media. By projecting patterns of light of varying spatial frequencies on a sample, we reconstruct quantitative, depth resolved images of absorption contrast. Images are reconstructed using a fast analytic inversion formula and a novel correction to the diffusion approximation for increased accuracy near boundaries. The method provides more accurate quantification of optical absorption and higher resolution than standard diffuse reflectance measurements.
© 2009 OSA
OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics
(110.0113) Imaging systems : Imaging through turbid media
ToC Category:
Medical Optics and Biotechnology
History
Original Manuscript: June 9, 2009
Revised Manuscript: August 3, 2009
Manuscript Accepted: August 4, 2009
Published: August 5, 2009
Virtual Issues
Vol. 4, Iss. 10 Virtual Journal for Biomedical Optics
Citation
Soren D. Konecky, Amaan Mazhar, David Cuccia, Anthony J. Durkin, John C. Schotland, and Bruce J. Tromberg, "Quantitative optical tomography of sub-surface heterogeneities using spatially modulated structured light," Opt. Express 17, 14780-14790 (2009)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-17-17-14780
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