Nanoparticle enhanced surface plasmon resonance biosensing: Application of gold nanorods

doi:10.1364/OE.17.019041

Nanoparticle enhanced surface plasmon resonance biosensing: Application of gold nanorods

Wing-Cheung Law, Ken-Tye Yong, Alexander Baev, Rui Hu, and Paras N. Prasad »View Author Affiliations

Optics Express, Vol. 17, Issue 21, pp. 19041-19046 (2009)
http://dx.doi.org/10.1364/OE.17.019041

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Abstract

In this report, we demonstrate the use of functionalized gold nanorods as amplification labels for ultra-sensitive surface plasmon resonance biosensing. Drastic sensitivity enhancement, owed to the electromagnetic interaction between the nanotag and the sensing film, was maximized using longitudinal plasmonic resonance of gold nanorods. The detection sensitivity of the nanorod-conjugated antibody is estimated to be ~40 pg/ml, which is 25 – 100 times more sensitive than the current reported values in the literature. This work paves the way to a new generation of ultra-sensitive nanoparticles-based biosensor platforms with maximized enhancement of sensitivity for ultra-fast screening and real-time detection of “hard-to-identify” biomolecules.

OCIS Codes
(120.5050) Instrumentation, measurement, and metrology : Phase measurement
(240.6680) Optics at surfaces : Surface plasmons

ToC Category:
Optics at Surfaces

History
Original Manuscript: August 7, 2009
Revised Manuscript: September 4, 2009
Manuscript Accepted: September 8, 2009
Published: October 7, 2009

Virtual Issues
Vol. 4, Iss. 12 Virtual Journal for Biomedical Optics

Citation
Wing-Cheung Law, Ken-Tye Yong, Alexander Baev, Rui Hu, and Paras N. Prasad, "Nanoparticle enhanced surface plasmon resonance biosensing: Application of gold nanorods," Opt. Express 17, 19041-19046 (2009)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-17-21-19041

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References

J. Homola, “Surface plasmon resonance sensors for detection of chemical and biological species,” Chem. Rev. 108(2), 462–493 (2008). [CrossRef] [PubMed]
P. N. Prasad, Nanophotonics (Wiley-Interscience: New York, 2004).
P. N. Prasad, Introduction to Biophotonics (Wiley-Interscience: New York, 2004).
H. P. Ho, W. C. Law, S. Y. Wu, C. Lin, and S. K. Kong, “Real-time optical biosensor based on differential phase measurement of surface plasmon resonance,” Biosens. Bioelectron. 20(10), 2177–2180 (2005). [CrossRef] [PubMed]
C. L. Wong, H. P. Ho, Y. K. Suen, S. K. Kong, Q. L. Chen, W. Yuan, and S. Y. Wu, “Real-time protein biosensor arrays based on surface plasmon resonance differential phase imaging,” Biosens. Bioelectron. 24(4), 606–612 (2008). [CrossRef] [PubMed]
A. N. Grigorenko, P. I. Nikitin, and A. V. Kabashin, “Phase jumps and interferometric surface plasmon resonance imaging,” Appl. Phys. Lett. 75(25), 3917–3919 (1999). [CrossRef]
H. P. Ho, W. C. Law, S. Y. Wu, X. H. Liu, S. P. Wong, C. Lin, and S. K. Kong, “Phase-sensitive surface plasmon resonance biosensor using the photoelastic modulation technique,” Sens. Actuators B Chem. 114(1), 80–84 (2006). [CrossRef]
W.-C. Law, P. Markowicz, K.-T. Yong, I. Roy, A. Baev, S. Patskovsky, A. V. Kabashin, H.-P. Ho, and P. N. Prasad, “Wide dynamic range phase-sensitive surface plasmon resonance biosensor based on measuring the modulation harmonics,” Biosens. Bioelectron. 23(5), 627–632 (2007). [CrossRef] [PubMed]
S. Y. Wu, H. P. Ho, W. C. Law, C. Lin, and S. K. Kong, “Highly sensitive differential phase-sensitive surface plasmon resonance biosensor based on the Mach-Zehnder configuration,” Opt. Lett. 29(20), 2378–2380 (2004). [CrossRef] [PubMed]
S. Patskovsky, M. Vallieres, M. Maisonneuve, I.-H. Song, M. Meunier, and A. V. Kabashin, “Designing efficient zero calibration point for phase-sensitive surface plasmon resonance biosensing,” Opt. Express 17(4), 2255–2263 (2009). [CrossRef] [PubMed]
L. He, M. D. Musick, S. R. Nicewarner, F. G. Salinas, S. J. Benkovic, M. J. Natan, and C. D. Keating, “Colloidal Au-Enhanced Surface Plasmon Resonance for Ultrasensitive Detection of DNA Hybridization,” J. Am. Chem. Soc. 122(38), 9071–9077 (2000). [CrossRef]
E. Hutter, S. Cha, J. F. Liu, J. Park, J. Yi, J. H. Fendler, and D. Roy, “Role of Substrate Metal in Gold Nanoparticle Enhanced Surface Plasmon Resonance Imaging,” J. Phys. Chem. B 105(1), 8–12 (2001). [CrossRef]
L. A. Lyon, M. D. Musick, and M. J. Natan, “Colloidal Au-enhanced surface plasmon resonance immunosensing,” Anal. Chem. 70(24), 5177–5183 (1998). [CrossRef] [PubMed]
J. S. Mitchell, Y. Wu, C. J. Cook, and L. Main, “Sensitivity enhancement of surface plasmon resonance biosensing of small molecules,” Anal. Biochem. 343(1), 125–135 (2005). [CrossRef] [PubMed]
T. K. Sau and C. J. Murphy, “Seeded high yield synthesis of short Au nanorods in aqueous solution,” Langmuir 20(15), 6414–6420 (2004). [CrossRef] [PubMed]
X. Liu, Q. Dai, L. Austin, J. Coutts, G. Knowles, J. Zou, H. Chen, and Q. Huo, “A one-step homogeneous immunoassay for cancer biomarker detection using gold nanoparticle probes coupled with dynamic light scattering,” J. Am. Chem. Soc. 130(9), 2780–2782 (2008). [CrossRef] [PubMed]
P. P. Markowicz, W. C. Law, A. Baev, P. N. Prasad, S. Patskovsky, and A. Kabashin, “Phase-sensitive time-modulated surface plasmon resonance polarimetry for wide dynamic range biosensing,” Opt. Express 15(4), 1745–1754 (2007). [CrossRef] [PubMed]

Anal. Biochem.

J. S. Mitchell, Y. Wu, C. J. Cook, and L. Main, “Sensitivity enhancement of surface plasmon resonance biosensing of small molecules,” Anal. Biochem. 343(1), 125–135 (2005). [CrossRef] [PubMed]

Anal. Chem.

L. A. Lyon, M. D. Musick, and M. J. Natan, “Colloidal Au-enhanced surface plasmon resonance immunosensing,” Anal. Chem. 70(24), 5177–5183 (1998). [CrossRef] [PubMed]

Appl. Phys. Lett.

A. N. Grigorenko, P. I. Nikitin, and A. V. Kabashin, “Phase jumps and interferometric surface plasmon resonance imaging,” Appl. Phys. Lett. 75(25), 3917–3919 (1999). [CrossRef]

Biosens. Bioelectron.

W.-C. Law, P. Markowicz, K.-T. Yong, I. Roy, A. Baev, S. Patskovsky, A. V. Kabashin, H.-P. Ho, and P. N. Prasad, “Wide dynamic range phase-sensitive surface plasmon resonance biosensor based on measuring the modulation harmonics,” Biosens. Bioelectron. 23(5), 627–632 (2007). [CrossRef] [PubMed]
H. P. Ho, W. C. Law, S. Y. Wu, C. Lin, and S. K. Kong, “Real-time optical biosensor based on differential phase measurement of surface plasmon resonance,” Biosens. Bioelectron. 20(10), 2177–2180 (2005). [CrossRef] [PubMed]
C. L. Wong, H. P. Ho, Y. K. Suen, S. K. Kong, Q. L. Chen, W. Yuan, and S. Y. Wu, “Real-time protein biosensor arrays based on surface plasmon resonance differential phase imaging,” Biosens. Bioelectron. 24(4), 606–612 (2008). [CrossRef] [PubMed]

Chem. Rev.

J. Homola, “Surface plasmon resonance sensors for detection of chemical and biological species,” Chem. Rev. 108(2), 462–493 (2008). [CrossRef] [PubMed]

J. Am. Chem. Soc.

L. He, M. D. Musick, S. R. Nicewarner, F. G. Salinas, S. J. Benkovic, M. J. Natan, and C. D. Keating, “Colloidal Au-Enhanced Surface Plasmon Resonance for Ultrasensitive Detection of DNA Hybridization,” J. Am. Chem. Soc. 122(38), 9071–9077 (2000). [CrossRef]
X. Liu, Q. Dai, L. Austin, J. Coutts, G. Knowles, J. Zou, H. Chen, and Q. Huo, “A one-step homogeneous immunoassay for cancer biomarker detection using gold nanoparticle probes coupled with dynamic light scattering,” J. Am. Chem. Soc. 130(9), 2780–2782 (2008). [CrossRef] [PubMed]

J. Phys. Chem. B

E. Hutter, S. Cha, J. F. Liu, J. Park, J. Yi, J. H. Fendler, and D. Roy, “Role of Substrate Metal in Gold Nanoparticle Enhanced Surface Plasmon Resonance Imaging,” J. Phys. Chem. B 105(1), 8–12 (2001). [CrossRef]

Langmuir

T. K. Sau and C. J. Murphy, “Seeded high yield synthesis of short Au nanorods in aqueous solution,” Langmuir 20(15), 6414–6420 (2004). [CrossRef] [PubMed]

Opt. Express

Opt. Lett.

S. Y. Wu, H. P. Ho, W. C. Law, C. Lin, and S. K. Kong, “Highly sensitive differential phase-sensitive surface plasmon resonance biosensor based on the Mach-Zehnder configuration,” Opt. Lett. 29(20), 2378–2380 (2004). [CrossRef] [PubMed]

Sens. Actuators B Chem.

H. P. Ho, W. C. Law, S. Y. Wu, X. H. Liu, S. P. Wong, C. Lin, and S. K. Kong, “Phase-sensitive surface plasmon resonance biosensor using the photoelastic modulation technique,” Sens. Actuators B Chem. 114(1), 80–84 (2006). [CrossRef]

Other

P. N. Prasad, Nanophotonics (Wiley-Interscience: New York, 2004).
P. N. Prasad, Introduction to Biophotonics (Wiley-Interscience: New York, 2004).

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