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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 17, Iss. 23 — Nov. 9, 2009
  • pp: 20847–20852

Silicon based total internal reflection bio and chemical sensing with spectral phase detection

Sergiy Patskovsky, In-Hyouk Song, Michel Meunier, and Andrei V. Kabashin  »View Author Affiliations

Optics Express, Vol. 17, Issue 23, pp. 20847-20852 (2009)

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Si-based total internal reflection (TIR) bio/chemical sensor presents an attractive alternative to Surface Plasmon Resonance (SPR) technology due to a relatively simple optical arrangement and technological implementation, as well as a relatively easy bio/chemical immobilization on Si/SiO2 surface with a number of novel attractive applications. This sensor is based on the control of phase difference between p- and s-polarized components of light reflected from Si/air or Si/water interface in TIR geometry and a high sensitivity of the sensor is granted by a high refractive index of Si (3.56 at 1200 nm). We study properties of TIR sensors in a configuration of spectral phase detection and identify conditions of maximal phase sensitive response. We also experimentally show that the detection limit of Si-based TIR sensor can be lowered down to a level of detection of commercially available SPR devices (10−6 Refractive Index Units, RIU) under the use of a proper low-noisy method of the phase control. The concept of Si-based TIR opens attractive prospects for the miniaturization of sensor devices, taking advantage of the advanced state of development of Si-based microfabrication technologies, while the proposed spectral phase detection scheme offers much easier packaging and calibration steps

© 2009 OSA

OCIS Codes
(120.5050) Instrumentation, measurement, and metrology : Phase measurement
(240.2130) Optics at surfaces : Ellipsometry and polarimetry

ToC Category:

Original Manuscript: September 9, 2009
Revised Manuscript: October 22, 2009
Manuscript Accepted: October 23, 2009
Published: October 30, 2009

Virtual Issues
Vol. 4, Iss. 13 Virtual Journal for Biomedical Optics

Sergiy Patskovsky, In-Hyouk Song, Michel Meunier, and Andrei V. Kabashin, "Silicon based total internal reflection bio and chemical sensing with spectral phase detection," Opt. Express 17, 20847-20852 (2009)

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