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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 17, Iss. 5 — Mar. 2, 2009
  • pp: 3997–4003

A comparison of retinal nerve fiber layer (RNFL) thickness obtained with frequency and time domain optical coherence tomography (OCT)

Donald C. Hood, Ali S. Raza, Kristine Y. Kay, Shlomit F. Sandler, Daiyan Xin, Robert Ritch, and Jeffrey M. Liebmann  »View Author Affiliations


Optics Express, Vol. 17, Issue 5, pp. 3997-4003 (2009)
http://dx.doi.org/10.1364/OE.17.003997


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Abstract

To diagnose glaucoma and other diseases of the retinal ganglion cell/ optic nerve, the thickness of the retinal nerve fiber layer (RNFL) is routinely measured with optical coherence tomography. Until recently, these OCT measurements were made almost exclusively with a time domain OCT (tdOCT) machine from a single manufacturer. Recently, a number of OCT machines, based upon an improved frequency domain OCT technology (fdOCT), have appeared. We compared measurements made using a new fdOCT machine to those from the older tdOCT machine. The results were comparable. More importantly, we learned that the key factor determining whether results from different machines will be comparable is the algorithm used to segment RNFL thickness, not the type of OCT.

© 2009 Optical Society of America

OCIS Codes
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
OCT in Glaucoma

History
Original Manuscript: July 2, 2008
Revised Manuscript: February 4, 2009
Manuscript Accepted: February 19, 2009
Published: March 2, 2009

Virtual Issues
Vol. 4, Iss. 5 Virtual Journal for Biomedical Optics
Interactive Science Publishing Focus Issue: Optical Coherence Tomography (OCT) (2009) Optics Express

Citation
Donald C. Hood, Ali S. Raza, Kristine Y. Kay, Shlomit F. Sandler, Daiyan Xin, Robert Ritch, and Jeffrey M. Liebmann, "A comparison of retinal nerve fiber layer (RNFL) thickness obtained with frequency and time domain optical coherence tomography (OCT)," Opt. Express 17, 3997-4003 (2009)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-17-5-3997


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References

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