OSA's Digital Library

Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 17, Iss. 5 — Mar. 2, 2009
  • pp: 4019–4036

Effect of image quality on tissue thickness measurements obtained with spectral domain-optical coherence tomography

Madhusudhanan Balasubramanian, Christopher Bowd, Gianmarco Vizzeri, Robert N. Weinreb, and Linda M. Zangwill  »View Author Affiliations


Optics Express, Vol. 17, Issue 5, pp. 4019-4036 (2009)
http://dx.doi.org/10.1364/OE.17.004019


View Full Text Article

Enhanced HTML    Acrobat PDF (1158 KB) ISP Components
Browse Datasets: MIDAS Click for help

Full-Text PDF contains links to datasets. See ISP homepage for software requirements and other information.





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

The purpose of this study was to investigate the effect of image quality on retinal nerve fiber layer (RNFL) and retinal thickness measurements obtained using three commercially available spectral domain-optical coherence tomographers (SD-OCT). Subjectively determined good, medium and poor quality images were obtained from four healthy and one glaucoma suspect eyes. RNFL and retinal thickness measurements were compared as a function of image quality. Results indicate that when image quality is within the range specified as acceptable by SD-OCT manufacturers, RNFL and retinal thickness measurements are comparable.

© 2009 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine

ToC Category:
OCT in Glaucoma

History
Original Manuscript: October 17, 2008
Revised Manuscript: January 17, 2009
Manuscript Accepted: February 19, 2009
Published: March 2, 2009

Virtual Issues
Vol. 4, Iss. 5 Virtual Journal for Biomedical Optics
Interactive Science Publishing Focus Issue: Optical Coherence Tomography (OCT) (2009) Optics Express

Citation
Madhusudhanan Balasubramanian, Christopher Bowd, Gianmarco Vizzeri, Robert N. Weinreb, and Linda M. Zangwill, "Effect of image quality on tissue thickness measurements obtained with spectral domain-optical coherence tomography," Opt. Express 17, 4019-4036 (2009)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-17-5-4019


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. T. C. Chen, B. Cense, M. C. Pierce, N. Nassif, B. H. Park, S. H. Yun, B. R. White, B. E. Bouma, G. J. Tearney, and J. F. de Boer, "Spectral domain optical coherence tomography: ultra-high speed, ultra-high resolution ophthalmic imaging," Arch. Ophthalmol. 123, 1715-1720 (2005). [CrossRef] [PubMed]
  2. J. F. de Boer, B. Cense, B. H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, "Improved signal-tonoise ratio in spectral-domain compared with time-domain optical coherence tomography," Opt. Lett. 28, 2067-2069 (2003). [CrossRef] [PubMed]
  3. J. G. Fujimoto, B. Bouma, G. J. Tearney, S. A. Boppart, C. Pitris, J. F. Southern, and M. E. Brezinski, "New technology for high-speed and high-resolution optical coherence tomography," Ann. N. Y. Acad. Sci. 838, 95-107 (1998). [CrossRef] [PubMed]
  4. N. Nassif, B. Cense, B. H. Park, S. H. Yun, T. C. Chen, B. E. Bouma, G. J. Tearney, and J. F. de Boer, "In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography," Opt. Lett. 29, 480-482 (2004). [CrossRef] [PubMed]
  5. M. E. van Velthoven, D. J. Faber, F. D. Verbraak, T. G. van Leeuwen, and M. D. de Smet, "Recent developments in optical coherence tomography for imaging the retina," Prog. Retin. Eye Res. 26, 57-77 (2007). [CrossRef]
  6. M. Wojtkowski, R. Leitgeb, A. Kowalczyk, T. Bajraszewski, and A. F. Fercher, "In vivo human retinal imaging by Fourier domain optical coherence tomography," J. Biomed. Opt. 7, 457-463 (2002). [CrossRef] [PubMed]
  7. M. Wojtkowski, V. Srinivasan, J. G. Fujimoto, T. Ko, J. S. Schuman, A. Kowalczyk, and J. S. Duker, "Three-dimensional retinal imaging with high-speed ultrahigh-resolution optical coherence tomography," Ophthalmology 112, 1734-1746 (2005). [CrossRef] [PubMed]
  8. A. O. Gonzalez-Garcia, G. Vizzeri, C. Bowd, F. A. Medeiros, L. M. Zangwill, and R. N. Weinreb, "Reproducibility of RTVue Retinal Nerve Fiber Layer Thickness and Optic Disc Measurements and Agreement with Stratus OCT Measurements," Am. J. Ophthalmol.in press. [PubMed]
  9. T. Mumcuoglu, G. Wollstein, M. Wojtkowski, L. Kagemann, H. Ishikawa, M. L. Gabriele, V. Srinivasan, J. G. Fujimoto, J. S. Duker, and J. S. Schuman, "Improved visualization of glaucomatous retinal damage using high-speed ultrahigh-resolution optical coherence tomography," Ophthalmology 115,. 782-789 e2 (2008). [CrossRef]
  10. V. J. Srinivasan, D. C. Adler, Y. Chen, I. Gorczynska, R. Huber, J. S. Duker, J. S. Schuman, and J. G. Fujimoto, "Ultrahigh-speed optical coherence tomography for three-dimensional and en face imaging of the retina and optic nerve head," Invest. Ophthalmol. Vis. Sci. 49, 5103-5110 (2008). [CrossRef] [PubMed]
  11. G. Vizzeri, R. N. Weinreb, A. O. Gonzalez-Garcia, C. Bowd, F. A. Medeiros, P. A. Sample, and L. M. Zangwill, "Agreement between Spectral-Domain and Time-Domain OCT for measuring RNFL thickness," Br. J. Ophthalmol.in press. [PubMed]
  12. N. G. Strouthidis, E. T. White, V. M. Owen, T. A. Ho, C. J. Hammond, and D. F. Garway-Heath, "Factors affecting the test-retest variability of Heidelberg retina tomograph and Heidelberg retina tomograph II measurements," Br. J. Ophthalmol. 89, 1427-1432 (2005). [CrossRef] [PubMed]
  13. C. Bowd, F. A. Medeiros, R. N. Weinreb, and L. M. Zangwill, "The effect of atypical birefringence patterns on glaucoma detection using scanning laser polarimetry with variable corneal compensation," Invest. Ophthalmol. Vis. Sci. 48, 223-227 (2007). [CrossRef] [PubMed]
  14. F. A. Medeiros, C. Bowd, L. M. Zangwill, C. Patel, and R. N. Weinreb, "Detection of glaucoma using scanning laser polarimetry with enhanced corneal compensation," Invest. Ophthalmol. Vis. Sci. 48, 3146-3153 (2007). [CrossRef] [PubMed]
  15. Z. Wu, M. Vazeen, R. Varma, V. Chopra, A. C. Walsh, L. D. LaBree, and S. R. Sadda, "Factors associated with variability in retinal nerve fiber layer thickness measurements obtained by optical coherence tomography," Ophthalmology 114, 1505-1512 (2007). [CrossRef] [PubMed]
  16. D. M. Stein, G. Wollstein, H. Ishikawa, E. Hertzmark, R. J. Noecker, and J. S. Schuman, "Effect of corneal drying on optical coherence tomography," Ophthalmology 113, 985-991 (2006). [CrossRef] [PubMed]
  17. 17. C. Y. Cheung, C. K. Leung, D. Lin, C. P. Pang, and D. S. Lam, Relationship between retinal nerve fiber layer measurement and signal strength in optical coherence tomography. Ophthalmology 115, 1347-51, 1351 e1-2 (2008). [CrossRef] [PubMed]
  18. M. L. Gabriele, H. Ishikawa, G. Wollstein, R. A. Bilonick, K. A. Townsend, L. Kagemann, M. Wojtkowski, V. J. Srinivasan, J. G. Fujimoto, J. S. Duker, and J. S. Schuman, "Optical coherence tomography scan circle location and mean retinal nerve fiber layer measurement variability," Invest. Ophthalmol. Vis. Sci. 49, 2315-2321 (2008). [CrossRef] [PubMed]
  19. G. Vizzeri, C. Bowd, F. A. Medeiros, R. N. Weinreb, and L. M. Zangwill, "Effect of improper scan alignment on retinal nerve fiber layer thickness measurements using Stratus optical coherence tomograph," J. Glaucoma 17, 341-349 (2008). [CrossRef] [PubMed]
  20. B. Liu, and M. E. Brezinski, "Theoretical and practical considerations on detection performance of time domain, Fourier domain, and swept source optical coherence tomography," J. Biomed. Opt. 12, 044007 (2007). [CrossRef] [PubMed]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited