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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 18, Iss. 11 — May. 24, 2010
  • pp: 11347–11359

Automated volumetric evaluation of stereoscopic disc photography

Juan Xu, Hiroshi Ishikawa, Gadi Wollstein, Richard A Bilonick, Larry Kagemann, Jamie E Craig, David A Mackey, Alex W Hewitt, and Joel S Schuman  »View Author Affiliations


Optics Express, Vol. 18, Issue 11, pp. 11347-11359 (2010)
http://dx.doi.org/10.1364/OE.18.011347


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Abstract

PURPOSE: To develop a fully automated algorithm (AP) to perform a volumetric measure of the optic disc using conventional stereoscopic optic nerve head (ONH) photographs, and to compare algorithm-produced parameters with manual photogrammetry (MP), scanning laser ophthalmoscope (SLO) and optical coherence tomography (OCT) measurements. METHODS: One hundred twenty-two stereoscopic optic disc photographs (61 subjects) were analyzed. Disc area, rim area, cup area, cup/disc area ratio, vertical cup/disc ratio, rim volume and cup volume were automatically computed by the algorithm. Latent variable measurement error models were used to assess measurement reproducibility for the four techniques. RESULTS: AP had better reproducibility for disc area and cup volume and worse reproducibility for cup/disc area ratio and vertical cup/disc ratio, when the measurements were compared to the MP, SLO and OCT methods. CONCLUSION: AP provides a useful technique for an objective quantitative assessment of 3D ONH structures.

© 2010 OSA

OCIS Codes
(100.0100) Image processing : Image processing
(100.2960) Image processing : Image analysis
(100.6890) Image processing : Three-dimensional image processing

ToC Category:
Image Processing

History
Original Manuscript: July 7, 2009
Revised Manuscript: October 1, 2009
Manuscript Accepted: October 11, 2009
Published: May 14, 2010

Virtual Issues
Vol. 5, Iss. 10 Virtual Journal for Biomedical Optics

Citation
Juan Xu, Hiroshi Ishikawa, Gadi Wollstein, Richard A Bilonick, Larry Kagemann, Jamie E Craig, David A Mackey, Alex W Hewitt, and Joel S Schuman, "Automated volumetric evaluation of stereoscopic disc photography," Opt. Express 18, 11347-11359 (2010)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-18-11-11347


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