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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 18, Iss. 18 — Aug. 30, 2010
  • pp: 19413–19428

Automatic segmentation of seven retinal layers in SDOCT images congruent with expert manual segmentation

Stephanie J. Chiu, Xiao T. Li, Peter Nicholas, Cynthia A. Toth, Joseph A. Izatt, and Sina Farsiu  »View Author Affiliations


Optics Express, Vol. 18, Issue 18, pp. 19413-19428 (2010)
http://dx.doi.org/10.1364/OE.18.019413


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Abstract

Segmentation of anatomical and pathological structures in ophthalmic images is crucial for the diagnosis and study of ocular diseases. However, manual segmentation is often a time-consuming and subjective process. This paper presents an automatic approach for segmenting retinal layers in Spectral Domain Optical Coherence Tomography images using graph theory and dynamic programming. Results show that this method accurately segments eight retinal layer boundaries in normal adult eyes more closely to an expert grader as compared to a second expert grader.

© 2010 OSA

OCIS Codes
(100.0100) Image processing : Image processing
(100.2960) Image processing : Image analysis
(110.4500) Imaging systems : Optical coherence tomography
(170.4470) Medical optics and biotechnology : Ophthalmology

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: July 15, 2010
Revised Manuscript: August 18, 2010
Manuscript Accepted: August 19, 2010
Published: August 27, 2010

Virtual Issues
Vol. 5, Iss. 13 Virtual Journal for Biomedical Optics

Citation
Stephanie J. Chiu, Xiao T. Li, Peter Nicholas, Cynthia A. Toth, Joseph A. Izatt, and Sina Farsiu, "Automatic segmentation of seven retinal layers in SDOCT images congruent with expert manual segmentation," Opt. Express 18, 19413-19428 (2010)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-18-18-19413


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