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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 18, Iss. 24 — Nov. 22, 2010
  • pp: 24595–24610

FloatingCanvas: quantification of 3D retinal structures from spectral-domain optical coherence tomography

Haogang Zhu, David P. Crabb, Patricio G. Schlottmann, Tuan Ho, and David F. Garway-Heath  »View Author Affiliations


Optics Express, Vol. 18, Issue 24, pp. 24595-24610 (2010)
http://dx.doi.org/10.1364/OE.18.024595


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Abstract

Spectral-domain optical coherence tomography (SD-OCT) provides volumetric images of retinal structures with unprecedented detail. Accurate segmentation algorithms and feature quantification in these images, however, are needed to realize the full potential of SD-OCT. The fully automated segmentation algorithm, FloatingCanvas, serves this purpose and performs a volumetric segmentation of retinal tissue layers in three-dimensional image volume acquired around the optic nerve head without requiring any pre-processing. The reconstructed layers are analyzed to extract features such as blood vessels and retinal nerve fibre layer thickness. Findings from images obtained with the RTVue-100 SD-OCT (Optovue, Fremont, CA, USA) indicate that FloatingCanvas is computationally efficient and is robust to the noise and low contrast in the images. The FloatingCanvas segmentation demonstrated good agreement with the human manual grading. The retinal nerve fibre layer thickness maps obtained with this method are clinically realistic and highly reproducible compared with time-domain StratusOCTTM.

© 2010 OSA

OCIS Codes
(100.0100) Image processing : Image processing
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: August 30, 2010
Revised Manuscript: October 7, 2010
Manuscript Accepted: October 10, 2010
Published: November 10, 2010

Citation
Haogang Zhu, David P. Crabb, Patricio G. Schlottmann, Tuan Ho, and David F. Garway-Heath, "FloatingCanvas: quantification of 3D retinal structures from spectral-domain optical coherence tomography," Opt. Express 18, 24595-24610 (2010)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-18-24-24595


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