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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 19, Iss. 3 — Jan. 31, 2011
  • pp: 1866–1883

Quantitative image contrast enhancement in time-gated transillumination of scattering media

David Sedarsky, Edouard Berrocal, and Mark Linne  »View Author Affiliations


Optics Express, Vol. 19, Issue 3, pp. 1866-1883 (2011)
http://dx.doi.org/10.1364/OE.19.001866


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Abstract

Experimental work in turbid media has shown that trans-illumination images can be significantly improved by limiting light collection to a subset of photons which are minimally distorted by scattering. The literature details numerous schemes (commonly termed ballistic imaging), most often based on time-gating and/or spatially filtering the detected light. However, due to the complex nature of the detected signal, analysis of this optical filtering process has been heretofore limited to qualitative comparisons of image results. In this article we present the implementation of a complete system model for the simulation of light propagation, including both the scattering medium and all stages of the optical train. Validation data from ballistic imaging (BI) measurements of monodisperse scatterers with diameter, d = 0.7 µm, at optical depths 5, 10, and 14, are compared with model results, showing excellent agreement. In addition, the validated model is subsequently applied to a modified time-gated optical system to probe the comparative performance of the BI system used in validation and the modified BI system. This instrument comparison examines scatterers with diameters of 0.7 and 15 µm at optical depths 10 and 14, and highlights the benefits of each system design for these specific scattering conditions. These results show that the modified optics configuration is more suitable for particles which are much larger than the incident wavelength, d >> λ, while the configuration employed in the validation system provides a better contrast for particle diameters on the order of the wavelength, d ~λ, where the scattering process exhibits a more homogeneous phase function. The insights and predictions made available by the full numerical model are important for the design of optimized imaging systems suited to specific turbid media, and make possible the quantitative understanding of both the effects of light propagation in the measurement and the performance of the complete imaging system.

© 2011 OSA

OCIS Codes
(290.4020) Scattering : Mie theory
(290.4210) Scattering : Multiple scattering
(290.7050) Scattering : Turbid media

ToC Category:
Scattering

History
Original Manuscript: November 2, 2010
Revised Manuscript: December 21, 2010
Manuscript Accepted: December 21, 2010
Published: January 18, 2011

Virtual Issues
Vol. 6, Iss. 2 Virtual Journal for Biomedical Optics

Citation
David Sedarsky, Edouard Berrocal, and Mark Linne, "Quantitative image contrast enhancement in time-gated transillumination of scattering media," Opt. Express 19, 1866-1883 (2011)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-19-3-1866


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References

  1. J. C. Hebden, S. R. Arridge, and D. T. Delpy, “Optical imaging in medicine: I. Experimental techniques,” Phys. Med. Biol. 42(5), 825–840 (1997). [CrossRef] [PubMed]
  2. C. Dunsby and P. M. W. French, “Techniques for depth-resolved imaging through turbid media including coherence-gated imaging,” J. Phys. D 36(14), R207–R227 (2003). [CrossRef]
  3. R. R. Alfano, S. G. Demos, and S. K. Gayen, “Advances in optical imaging of biomedical media,” Ann. N. Y. Acad. Sci. 820(1 Imaging Brain), 248–271 (1997). [CrossRef] [PubMed]
  4. W. F. Cheong, S. A. Prahl, and A. J. Welch, “A review of the optical properties of biological tissues,” IEEE J. Quantum Electron. 26(12), 2166–2185 (1990). [CrossRef]
  5. J. M. Schmitt and G. Kumar, “Optical scattering properties of soft tissue: a discrete particle model,” Appl. Opt. 37(13), 2788–2797 (1998). [CrossRef]
  6. L. V. Wang and H. Wu, Biomedical Optics: Principles and Imaging (Wiley, Hoboken, NJ, 2007).
  7. K. M. Yoo and R. R. Alfano, “Time-resolved coherent and incoherent components of forward light scattering in random media,” Opt. Lett. 15(6), 320–322 (1990). [CrossRef] [PubMed]
  8. L. Wang, P. P. Ho, C. Liu, G. Zhang, and R. R. Alfano, “Ballistic 2-d imaging through scattering walls using an ultrafast optical Kerr gate,” Science 253(5021), 769–771 (1991). [CrossRef] [PubMed]
  9. G. E. Anderson, F. Liu, and R. R. Alfano, “Microscope imaging through highly scattering media,” Opt. Lett. 19(13), 981–983 (1994). [CrossRef] [PubMed]
  10. Q. Z. Wang, X. Liang, L. Wang, P. P. Ho, and R. R. Alfano, “Fourier spatial filter acts as a temporal gate for light propagating through a turbid medium,” Opt. Lett. 20(13), 1498–1500 (1995). [CrossRef] [PubMed]
  11. H. Ramachandran and A. Narayanan, “Two-dimensional imaging through turbid media using a continuous wave light source,” Opt. Commun. 154(5-6), 255–260 (1998). [CrossRef]
  12. S. Mujumdar and H. Ramachandran, “Imaging through turbid media using polarization modulation: Dependence on scattering anisotropy,” Opt. Commun. 241(1-3), 1–9 (2004). [CrossRef]
  13. R. Sala and M. C. Richardson, “Optical Kerr effect induced by ultrashort laser pulses,” Phys. Rev. A 12(3), 1036–1047 (1975). [CrossRef]
  14. M. A. Duguay and A. T. Mattick, “Ultrahigh speed photography of picosecond light pulses and echoes,” Appl. Opt. 10(9), 2162–2170 (1971). [CrossRef] [PubMed]
  15. L. M. Wang, P. P. Ho, X. Liang, H. Dai, and R. R. Alfano, “Kerr - Fourier imaging of hidden objects in thick turbid media,” Opt. Lett. 18(3), 241–243 (1993). [CrossRef] [PubMed]
  16. R. R. Alfano, X. Liang, L. Wang, and P. P. Ho, “Time-resolved imaging of translucent droplets in highly scattering turbid media,” Science 264(5167), 1913–1915 (1994). [CrossRef] [PubMed]
  17. P. A. Galland, X. Liang, and L. Wang, “Time-resolved optical imaging of jet sprays and droplets in highly scattering medium,” Proc. Am. Soc. Mech. Eng. HTD-321,585–588, (1995).
  18. M. Paciaroni, “Time-gated Ballistic Imaging through scattering media with applications to liquid spray combustion” (Ph.D. Thesis, Colorado School of Mines, 2004).
  19. M. Paciaroni and M. Linne, “Single-shot, two-dimensional ballistic imaging through scattering media,” Appl. Opt. 43(26), 5100–5109 (2004). [CrossRef] [PubMed]
  20. D. Sedarsky, M. Paciaroni, E. Berrocal, P. Petterson, J. Zelina, J. Gord, and M. Linne, “Model validation image data for breakup of a liquid jet in crossflow: part I,” Exp. Fluids 49(2), 391–408 (2010). [CrossRef]
  21. D. Sedarsky, J. Gord, C. Carter, T. R. Meyer, and M. A. Linne, “Fast-framing ballistic imaging of velocity in an aerated spray,” Opt. Lett. 34(18), 2748–2750 (2009). [CrossRef] [PubMed]
  22. M. Linne, D. Sedarsky, T. Meyer, J. Gord, and C. Carter, “Ballistic imaging in the near-field of an effervescent spray,” Exp. Fluids 49(4), 911–923 (2010). [CrossRef]
  23. M. Linne, M. Paciaroni, T. Hall, and T. Parker, “Ballistic imaging of the near field in a diesel spray,” Exp. Fluids 40(6), 836–846 (2006). [CrossRef]
  24. M. A. Linne, M. Paciaroni, E. Berrocal, and D. Sedarsky, “Ballistic Imaging of Liquid Breakup Processes in Dense Sprays,” Proc. Combust. Inst. 32(2), 2147–2161 (2009). [CrossRef]
  25. Y. Kuga and A. Ishimaru, “Modulation transfer function and image transmission through randomly distributed spherical particles,” J. Opt. Soc. Am. A 2(12), 2330–2335 (1985). [CrossRef]
  26. P. Bruscaglioni, P. Donelli, A. Ismaelli, and G. Zaccanti, “Monte Carlo calculations of the modulation transfer function of an optical system operating in a turbid medium,” Appl. Opt. 32(15), 2813–2824 (1993). [CrossRef] [PubMed]
  27. J. C. Hebden, “Evaluating the spatial resolution performance of a time-resolved optical imaging system,” Med. Phys. 19(4), 1081–1087 (1992). [CrossRef] [PubMed]
  28. J. C. Hebden and R. A. Kruger, “Transillumination imaging performance: a time-of-flight imaging system,” Med. Phys. 17(3), 351–356 (1990). [CrossRef] [PubMed]
  29. E. Berrocal, D. L. Sedarsky, M. E. Paciaroni, I. V. Meglinski, and M. A. Linne, “Laser light scattering in turbid media Part I: Experimental and simulated results for the spatial intensity distribution,” Opt. Express 15(17), 10649–10665 (2007). [CrossRef] [PubMed]
  30. E. Berrocal, D. L. Sedarsky, M. E. Paciaroni, I. V. Meglinski, and M. A. Linne, “Laser light scattering in turbid media Part II: Spatial and temporal analysis of individual scattering orders via Monte Carlo simulation,” Opt. Express 17(16), 13792–13809 (2009). [CrossRef] [PubMed]
  31. E. Berrocal, “Multiple scattering of light in optical diagnostics of dense sprays and other complex turbid media” (Ph.D. Thesis, Cranfield University, 2006).
  32. D. Sedarsky, Ballistic imaging of transient phenomena in turbid media (Ph.D. Thesis, Lund University, 2009).
  33. H. Urey, “Spot size, depth-of-focus, and diffraction ring intensity formulas for truncated Gaussian beams,” Appl. Opt. 43(3), 620–625 (2004). [CrossRef] [PubMed]
  34. M. I. Mishchenko, J. W. Hovenier, and L. D. Travis, Light Scattering by Nonspherical Particles: Theory, Measurements, and Applications (Academic Press, London, 2000).
  35. D. Watson, N. Hagen, J. Diver, P. Marchand, and M. Chachisvilis, “Elastic light scattering from single cells: orientational dynamics in optical trap,” Biophys. J. 87(2), 1298–1306 (2004). [CrossRef] [PubMed]
  36. D. Barnhart, “Optica software,” http://www.opticasoftware.com .
  37. Wolfram Research, Inc., Mathematica, Version 7.0, Champaign, IL (2008).
  38. E. Hecht, Optics, 4th ed. (Addison Wesley Longman Inc., Reading, MA, 2002). [PubMed]

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