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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 20, Iss. 23 — Nov. 5, 2012
  • pp: 25357–25368

Extracting and compensating dispersion mismatch in ultrahigh-resolution Fourier domain OCT imaging of the retina

WooJhon Choi, Bernhard Baumann, Eric A. Swanson, and James G. Fujimoto  »View Author Affiliations

Optics Express, Vol. 20, Issue 23, pp. 25357-25368 (2012)

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We present a numerical approach to extract the dispersion mismatch in ultrahigh-resolution Fourier domain optical coherence tomography (OCT) imaging of the retina. The method draws upon an analogy with a Shack-Hartmann wavefront sensor. By exploiting mathematical similarities between the expressions for aberration in optical imaging and dispersion mismatch in spectral / Fourier domain OCT, Shack-Hartmann principles can be extended from the two-dimensional paraxial wavevector space (or the x-y plane in the spatial domain) to the one-dimensional wavenumber space (or the z-axis in the spatial domain). For OCT imaging of the retina, different retinal layers, such as the retinal nerve fiber layer (RNFL), the photoreceptor inner and outer segment junction (IS/OS), or all the retinal layers near the retinal pigment epithelium (RPE) can be used as point source beacons in the axial direction, analogous to point source beacons used in conventional two-dimensional Shack-Hartman wavefront sensors for aberration characterization. Subtleties regarding speckle phenomena in optical imaging, which affect the Shack-Hartmann wavefront sensor used in adaptive optics, also occur analogously in this application. Using this approach and carefully suppressing speckle, the dispersion mismatch in spectral / Fourier domain OCT retinal imaging can be successfully extracted numerically and used for numerical dispersion compensation to generate sharper, ultrahigh-resolution OCT images.

© 2012 OSA

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(260.2030) Physical optics : Dispersion

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: June 27, 2012
Revised Manuscript: October 4, 2012
Manuscript Accepted: October 9, 2012
Published: October 24, 2012

Virtual Issues
Vol. 7, Iss. 12 Virtual Journal for Biomedical Optics

WooJhon Choi, Bernhard Baumann, Eric A. Swanson, and James G. Fujimoto, "Extracting and compensating dispersion mismatch in ultrahigh-resolution Fourier domain OCT imaging of the retina," Opt. Express 20, 25357-25368 (2012)

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