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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 20, Iss. 7 — Mar. 26, 2012
  • pp: 7195–7205

All-optical phase modulation for integrated interferometric biosensors

Stefania Dante, Daphné Duval, Borja Sepúlveda, Ana Belen González-Guerrero, José Ramón Sendra, and Laura M. Lechuga  »View Author Affiliations

Optics Express, Vol. 20, Issue 7, pp. 7195-7205 (2012)

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We present the theoretical and the experimental implementation of an all-optical phase modulation system in integrated Mach-Zehnder Interferometers to solve the drawbacks related to the periodic nature of the interferometric signal. Sensor phase is tuned by modulating the emission wavelength of low-cost commercial laser diodes by changing their output power. FFT deconvolution of the signal allows for direct phase readout, immune to sensitivity variations and to light intensity fluctuations. This simple phase modulation scheme increases the signal-to-noise ratio of the measurements in one order of magnitude, rendering in a sensor with a detection limit of 1.9·10−7 RIU. The viability of the all-optical modulation approach is demonstrated with an immunoassay detection as a biosensing proof of concept.

© 2012 OSA

OCIS Codes
(120.3180) Instrumentation, measurement, and metrology : Interferometry
(120.5060) Instrumentation, measurement, and metrology : Phase modulation
(130.3120) Integrated optics : Integrated optics devices
(280.1415) Remote sensing and sensors : Biological sensing and sensors
(280.4788) Remote sensing and sensors : Optical sensing and sensors

ToC Category:

Original Manuscript: December 5, 2011
Revised Manuscript: February 3, 2012
Manuscript Accepted: February 6, 2012
Published: March 14, 2012

Virtual Issues
Vol. 7, Iss. 5 Virtual Journal for Biomedical Optics

Stefania Dante, Daphné Duval, Borja Sepúlveda, Ana Belen González-Guerrero, José Ramón Sendra, and Laura M. Lechuga, "All-optical phase modulation for integrated interferometric biosensors," Opt. Express 20, 7195-7205 (2012)

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