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Microfluidics integration of aperiodic plasmonic arrays for spatial-spectral optical detectionSylvanus Y. Lee, Gary F. Walsh, and Luca Dal Negro »View Author Affiliations
Sylvanus Y. Lee,1,2
Gary F. Walsh,1,3
and Luca Dal Negro1,4,*
1Department of Electrical and Computer Engineering & Photonics Center, Boston University, 8 St. Mary’s St., Boston, Massachusetts 02215, USA 2Department of Mechanical Engineering, Boston University, 110 Cummington St., Boston, Massachusetts 02215, USA 3US Army NSRDEC, Nanomaterials Science Team, Kansas Street, Natick, Massachusetts 01760, USA 4Division of Materials Science and Engineering, 8 St. Mary’s St., Boston, Massachusetts 02215, USA *Corresponding author: dalnegro@bu.edu |
Optics Express, Vol. 21, Issue 4, pp. 4945-4957 (2013)
http://dx.doi.org/10.1364/OE.21.004945
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Abstract
We demonstrate successful integration of aperiodic arrays of metal nanoparticles with microfluidics technology for optical sensing using the spectral-colorimetric responses of nanostructured arrays to refractive index variations. Different aperiodic arrays of gold (Au) nanoparticles with varying interparticle separations and Fourier spectral properties are fabricated using Electron Beam Lithography (EBL) and integrated with polydimethylsiloxane (PDMS) microfluidics structures by soft-lithographic micro-imprint techniques. The spectral shifts of scattering spectra and the distinctive modifications of structural color patterns induced by refractive index variations were simultaneously measured inside microfluidic flow cells by dark-field spectroscopy and image correlation analysis in the visible spectral range. The integration of engineered aperiodic arrays of Au nanoparticles with microfluidics devices provides a novel sensing platform with multiplexed spatial-spectral responses for opto-fluidics applications and lab-on-a-chip optical biosensing.
© 2013 OSA
OCIS Codes
(290.3030) Scattering : Index measurements
(330.1710) Vision, color, and visual optics : Color, measurement
(280.4788) Remote sensing and sensors : Optical sensing and sensors
ToC Category:
Sensors
History
Original Manuscript: November 8, 2012
Revised Manuscript: February 12, 2013
Manuscript Accepted: February 14, 2013
Published: February 21, 2013
Virtual Issues
Vol. 8, Iss. 3 Virtual Journal for Biomedical Optics
Citation
Sylvanus Y. Lee, Gary F. Walsh, and Luca Dal Negro, "Microfluidics integration of aperiodic plasmonic arrays for spatial-spectral optical detection," Opt. Express 21, 4945-4957 (2013)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-21-4-4945
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- A. M. Christensen, D. A. Chang-Yen, and B. K. Gale, “Characterization of interconnects used in PDMS microfluidic systems,” J. Micromech. Microeng.15(5), 928–934 (2005). [CrossRef]
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- J. Trevino, S. F. Liew, H. Noh, H. Cao, and L. Dal Negro, “Geometrical structure, multifractal spectra and localized optical modes of aperiodic Vogel spirals,” Opt. Express20(3), 3015–3033 (2012). [CrossRef] [PubMed]
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