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Optics Express

Optics Express

  • Editor: Andrew M. Weiner
  • Vol. 22, Iss. 8 — Apr. 21, 2014
  • pp: 8985–8995

In vivo imaging of middle-ear and inner-ear microstructures of a mouse guided by SD-OCT combined with a surgical microscope

Nam Hyun Cho, Jeong Hun Jang, Woonggyu Jung, and Jeehyun Kim  »View Author Affiliations


Optics Express, Vol. 22, Issue 8, pp. 8985-8995 (2014)
http://dx.doi.org/10.1364/OE.22.008985


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Abstract

We developed an augmented-reality system that combines optical coherence tomography (OCT) with a surgical microscope. By sharing the common optical path in the microscope and OCT, we could simultaneously acquire OCT and microscope views. The system was tested to identify the middle-ear and inner-ear microstructures of a mouse. Considering the probability of clinical application including otorhinolaryngology, diseases such as middle-ear effusion were visualized using in vivo mouse and OCT images simultaneously acquired through the eyepiece of the surgical microscope during surgical manipulation using the proposed system. This system is expected to realize a new practical area of OCT application.

© 2014 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(170.4940) Medical optics and biotechnology : Otolaryngology

ToC Category:
Imaging Systems

History
Original Manuscript: January 30, 2014
Revised Manuscript: March 20, 2014
Manuscript Accepted: March 21, 2014
Published: April 7, 2014

Virtual Issues
Vol. 9, Iss. 6 Virtual Journal for Biomedical Optics

Citation
Nam Hyun Cho, Jeong Hun Jang, Woonggyu Jung, and Jeehyun Kim, "In vivo imaging of middle-ear and inner-ear microstructures of a mouse guided by SD-OCT combined with a surgical microscope," Opt. Express 22, 8985-8995 (2014)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-22-8-8985


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