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Optics Express

Optics Express

  • Editor: J. H. Eberly
  • Vol. 3, Iss. 5 — Aug. 31, 1998
  • pp: 190–197

A fast, robust pattern recognition system for low light level image registration and its application to retinal imaging

A. R. Wade and F. W. Fitzke  »View Author Affiliations

Optics Express, Vol. 3, Issue 5, pp. 190-197 (1998)

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We describe an image processing system which we have developed to align autofluorescence and high-magnification images taken with a laser scanning ophthalmoscope. The low signal to noise ratio of these images makes pattern recognition a non-trivial task. However, once n images are aligned and averaged, the noise levels drop by a factor of √n and the image quality is improved. We include examples of autofluorescence images and images of the cone photoreceptor mosaic obtained using this system.

© Optical Society of America

OCIS Codes
(100.5010) Image processing : Pattern recognition
(330.4300) Vision, color, and visual optics : Vision system - noninvasive assessment

ToC Category:
Research Papers

Original Manuscript: May 11, 1998
Revised Manuscript: May 7, 1998
Published: August 31, 1997

Alex Wade and Frederick Fitzke, "A fast, robust pattern recognition asystem for low light level image registration and its application to retinal imaging," Opt. Express 3, 190-197 (1998)

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  1. F. C. Delori, "Spectrophotometer for noninvasive measurement of intrinsic fluorescence and reflectance of the ocular fundus," Appl. Opt. 33, 7439-7452 (1994). [CrossRef] [PubMed]
  2. A. von Ruckman, F. W. Fitzke and A. C. Bird, "Distribution of fundus autofluorescence with a scanning laser ophthalmoscope," Br. J. Ophthal. 79, 407-412 (1995). [CrossRef]
  3. A. R. Wade, and F. W. Fitzke, " In-vivo imaging of the human cone photoreceptor mosaic using a confocal LSO," Lasers and Light in Ophthalmology 1998. (In Press).
  4. L. G. Brown, "A survey of image registration techniques," Computing Surveys 24, 325-376 (1992). [CrossRef]

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