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Optics Express

Optics Express

  • Editor: J. H. Eberly
  • Vol. 4, Iss. 11 — May. 24, 1999
  • pp: 475–480

Sensing lesions in tissues with light

S. K. Gayen and R. R. Alfano  »View Author Affiliations

Optics Express, Vol. 4, Issue 11, pp. 475-480 (1999)

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The use of light for probing and imaging of biomedical media offers the promise for development of safe, noninvasive, and inexpensive clinical imaging modalities with diagnostic ability. Various properties of light together with the ways it interacts with biological tissues may provide ‘multiple windows’ to peer inside body organs. Principles and methods for extraction of information about body functions and lesions that capitalize on temporal, spectral, polarization, and spatial characteristics of transmitted light are briefly outlined. As illustrations of the potential and efficacy of light-based techniques, time-sliced and spectroscopic images of normal and cancerous human breast tissues recorded with a femtosecond Ti:sapphire laser and a broadly tunable Cr:forsterite laser, respectively, are presented.

© Optical Society of America

OCIS Codes
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.6920) Medical optics and biotechnology : Time-resolved imaging
(290.7050) Scattering : Turbid media

ToC Category:
Focus Issue: Sensing

Original Manuscript: April 8, 1999
Published: May 24, 1999

S. Gayen and R. Alfano, "Sensing lesions in tissues with light," Opt. Express 4, 475-480 (1999)

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