Modeling of sensitivity and resolution to an included object in homogeneous scattering media and in MRI-derived breast maps

doi:10.1364/OE.5.000203

Optics Express

Editor: J. H. Eberly
Vol. 5, Iss. 10 — Nov. 8, 1999
pp: 203–219

Modeling of sensitivity and resolution to an included object in homogeneous scattering media and in MRI-derived breast maps

Yaling Pei, Feng Bao Lin, and Randall Barbour »View Author Affiliations

Optics Express, Vol. 5, Issue 10, pp. 203-219 (1999)
http://dx.doi.org/10.1364/OE.5.000203

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Abstract
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References (13)
Cited By
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Abstract

We have examined the measured sensitivity and edge resolution to an included tumor in MR-derived maps of the breast exposed to NIR illumination. A large parameter space was explored, enabling a systematic examination of the influence that measurement parameters (e.g., view angle, source position, wavelength) and target medium parameters (e.g., breast and tumor size, background tissue properties, and tumor contrast) have on the computed responses. The significance of these finding on data collection schemes for imaging studies is discussed.

[Optical Society of America ]

OCIS Codes
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.3830) Medical optics and biotechnology : Mammography
(290.4210) Scattering : Multiple scattering

ToC Category:
Research Papers

History
Original Manuscript: August 9, 1999
Published: November 8, 1999

Citation
Yaling Pei, Feng Bao Lin, and Randall Barbour, "Modeling of sensitivity and resolution to an included object in homogeneous scattering media and in MRI-derived breast maps," Opt. Express 5, 203-219 (1999)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-5-10-203

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References

S. Fantini, S. A. Walker, M. A. Franceschini., A. E. Cerussi, et al., "Characterization of breast tumors by frequency-domain optical mammography," In Advance in Optical Imaging and Photon Migration, J. G. Fujimoto et al, ed., Vol. 21 of OSA Proceeding Series (Optical Society of America, Whashington, D. C., 1998), pp. 289-293.
V. Ntziachristos, X. H. Ma, M. Schnall, A. Yoldh and B. Chance, "Concurrent multi-channel time-resolved NIR with MR mammography instrumentation and initial clinical results," Ibid., pp. 284-288.
R. L. Barbour, R. Andronica, Q. Sha, H. L. Graber, and I. Soller, "Development and evaluation of the IRIS- OPTIscanner, a general-purpose optical tomographic imaging system," Ibid., pp. 251-255.
B.W. Pogue, M. Testorf, U. L. Osterberg, and K. D. Paulsen, "Development of quantitative imaging in frequency-domain diffuse optical tomography for breast cancer detection," Ibid., pp. 245-250.
S. B. Colak, D. G. Papaioannou, G. W. 't Hooft, M. B. van der Mark, et al., "Tomographic image reconstruction from optical projections in light-diffusing media," Appl. Opt. 36,180-213 (1997). [CrossRef] [PubMed]
R. L. Barbour, H. L. Graber, J. Chang, S.-L. S. Barbour, P. C. Koo and R. Aronson, "MRI-guided optical tomography: Prospects and computation for a new imaging method," in Computational Science & Engineering, (Institute of Electical and Electronic Engineerings, New York, 1995), pp. 63-76. [CrossRef]
"VoxelView 2.5 User's Guide," Vital Images, Inc. www.vitalimages.com (1995).
H. W. Shen and C. R. Johnson, "Semi-automatic image segmentation: A biomedical thresholding approach," Technical Report UUCS-94-019, Dept. of CS, Univ. of Utah (1994).
D. F. Watson, "Computing the n-dimensional Delaunay tesselation with applications to Voronoi polytopes," Computer Journal 24(2), 167-172 (1981). [CrossRef]
N. Weatherill, and O. Hassan, "Efficient three-dimensional grid generation using the Delaunay triangulation," Proceeding of the 1st European CFD Conference, 1 (1992).
R. Beck, B. Erdmann and R. Roitzsch, "Kaskade 3.0 - An object-oriented adaptive finite element code," Technical report TR 95-4, Konrad-Zuse-Zentrum f?r Informationstechnik, Berlin (1995).
T. L. Troy, D. L. Page, D. L. and E. M. Sevick-Muraca, "Optical properties of normal and diseased breast tissues: Prognosis for optical mammography," J. Biomedical Opt. 3, 342-355 (1996). [CrossRef]
H. L. Graber, Y. Pei, R. Aronson, H. and R. L. Barbour, "Dependence of object sensitivity and resolution on optical thickness of scattering media," Appl. Opt. submitted.

Other

S. Fantini, S. A. Walker, M. A. Franceschini., A. E. Cerussi, et al., "Characterization of breast tumors by frequency-domain optical mammography," In Advance in Optical Imaging and Photon Migration, J. G. Fujimoto et al, ed., Vol. 21 of OSA Proceeding Series (Optical Society of America, Whashington, D. C., 1998), pp. 289-293.
V. Ntziachristos, X. H. Ma, M. Schnall, A. Yoldh and B. Chance, "Concurrent multi-channel time-resolved NIR with MR mammography instrumentation and initial clinical results," Ibid., pp. 284-288.
R. L. Barbour, R. Andronica, Q. Sha, H. L. Graber, and I. Soller, "Development and evaluation of the IRIS- OPTIscanner, a general-purpose optical tomographic imaging system," Ibid., pp. 251-255.
B.W. Pogue, M. Testorf, U. L. Osterberg, and K. D. Paulsen, "Development of quantitative imaging in frequency-domain diffuse optical tomography for breast cancer detection," Ibid., pp. 245-250.
S. B. Colak, D. G. Papaioannou, G. W. 't Hooft, M. B. van der Mark, et al., "Tomographic image reconstruction from optical projections in light-diffusing media," Appl. Opt. 36,180-213 (1997). [CrossRef] [PubMed]
R. L. Barbour, H. L. Graber, J. Chang, S.-L. S. Barbour, P. C. Koo and R. Aronson, "MRI-guided optical tomography: Prospects and computation for a new imaging method," in Computational Science & Engineering, (Institute of Electical and Electronic Engineerings, New York, 1995), pp. 63-76. [CrossRef]
"VoxelView 2.5 User's Guide," Vital Images, Inc. www.vitalimages.com (1995).
H. W. Shen and C. R. Johnson, "Semi-automatic image segmentation: A biomedical thresholding approach," Technical Report UUCS-94-019, Dept. of CS, Univ. of Utah (1994).
D. F. Watson, "Computing the n-dimensional Delaunay tesselation with applications to Voronoi polytopes," Computer Journal 24(2), 167-172 (1981). [CrossRef]
N. Weatherill, and O. Hassan, "Efficient three-dimensional grid generation using the Delaunay triangulation," Proceeding of the 1st European CFD Conference, 1 (1992).
R. Beck, B. Erdmann and R. Roitzsch, "Kaskade 3.0 - An object-oriented adaptive finite element code," Technical report TR 95-4, Konrad-Zuse-Zentrum f?r Informationstechnik, Berlin (1995).
T. L. Troy, D. L. Page, D. L. and E. M. Sevick-Muraca, "Optical properties of normal and diseased breast tissues: Prognosis for optical mammography," J. Biomedical Opt. 3, 342-355 (1996). [CrossRef]
H. L. Graber, Y. Pei, R. Aronson, H. and R. L. Barbour, "Dependence of object sensitivity and resolution on optical thickness of scattering media," Appl. Opt. submitted.

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