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Optics Express

Optics Express

  • Editor: J. H. Eberly
  • Vol. 8, Iss. 3 — Jan. 29, 2001
  • pp: 223–231

Interfering diffusive photon-density waves with an absorbing-fluorescent inhomogeneity

X. Intes, B. Chance, M.J. Holboke, and A.G. Yodh  »View Author Affiliations

Optics Express, Vol. 8, Issue 3, pp. 223-231 (2001)

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This work reports an investigation of the fluorescent field re-emitted by an object embedded in a highly scattering media illuminated by two-interfering sources. Simulations in the frequency domain with a finite difference method solving the diffusion equation were performed. The media considered had features typical of a soft-compressed breast. An absorbing-fluorescent inhomogeneity was embedded in the center of the slab. A qualitative study of the re-emitted field was achieved. The re-emitted field was found to possess unique features characteristic of the two-interfering sources excitation, i.e. null intensity when the object was between the two sources and a 180° transition crossing this position. Those features, when performing a scan of the two sources, permitted accurate localization of the inhomogeneity. Moreover, even when the detector was not placed on the mid-plane of the two sources, the re-emitted field still exhibited the interfering characteristic pattern, which was not seen at the excitation wavelength. Thus, for such configurations, the re-emitted field still possessed the specific sensitivity of phased array emission conversely to the excitation wavelength.

© Optical Society of America

OCIS Codes
(110.5100) Imaging systems : Phased-array imaging systems
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.5270) Medical optics and biotechnology : Photon density waves
(170.5280) Medical optics and biotechnology : Photon migration
(260.2510) Physical optics : Fluorescence

ToC Category:
Research Papers

Original Manuscript: November 9, 2000
Published: January 29, 2001

Xavier Intes, Britton Chance, Monica Holboke, and Arjun Yodh, "Interfering diffusive photon-density waves with an absorbing-fluorescent inhomogeneity," Opt. Express 8, 223-231 (2001)

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