Abstract

We combine real-time feature recognition with holographic optical tweezers to automatically trap, assemble, and sort micron-sized colloidal particles. Closed loop control will enable new applications of optical micromanipulation in biology, medicine, materials science, and possibly quantum computation.

© 2006 Optical Society of America

» View Full Text: Acrobat PDF (200 KB)

History
Original Manuscript: October 27, 2006
Manuscript Accepted: December 16, 2006
Revised Manuscript: December 15, 2006
Published: December 22, 2006

References

1. A. Ashkin, J. M. Dziedzic, J. E. Bjorkholm, and S. Chu, "Observation of a single-beam gradient force optical trap for dielectric particles," Opt. Lett. 11(5), 288-290 (1986).
2. K. Svoboda and S. M. Block, "Force and Velocity Measured for Single Kinesin Molecules," Cell 77, 773-784 (1994). [CrossRef]
3. H. Yin, M. D. Wang, K. Svoboda, R. Landick, S. M. Block, and J. Gelles, "Transcription against an applied force," Science 270, 1653-1657 (1995). [CrossRef]
4. D. G. Grier, "Optical tweezers in colloid and interface science," Current Opinion Colloid Interface Sci. 2, 264-270 (1997).
5. K. Sasaki, M. Koshio, H. Misawa, N. Kitamura, and H. Masuhara, "Pattern formation and flow control of fine particles by laser-scanning micromanipulation," Opt. Lett. 16(19), 1463-1465 (1991).
6. E. R. Dufresne and D. G. Grier, "Optical tweezer arrays and optical substrates created with diffractive optics," Rev. Sci. Instrum. 69, 1974 (1998). [CrossRef]
7. R. L. Eriksen, P. C. Mogensen, and J. Gluckstad, "Multiple beam optical tweezres generated by the generalized phase contrast method," Opt. Lett. 27, 267 (2002).
8. K. Ladavac, K. Kasza, and D. G. Grier, "Sorting mesoscopic objects with periodic potential landscapes: Optical Fractionation," Phys. Rev. E 70, 010,901 (2004).
9. M. P. Macdonald, G. C. Spalding, and K. Dholakia, "Microfluidic sorting in an optical lattice," Nature 426, 421 (2003). [CrossRef]
10. T. L. Gustavson, A. P. Chikkatur, A. E. Leanhardt, A. Gorlitz, S. Gupta, D. E. Pritchard, andW. Ketterle, "Transport of Bose-Einstein Condensates with optical tweezers," Phys. Rev. Lett. 88, 020401 (2002).
11. J. Kim, S. Pau, Z. Ma, H. R. McLellan, J. V. Gates, A. Kornblit, R. E. Slusher, R. M. Jopson, I. Kang, and M. Dinu, "System Design for Large-Scale Ion Trap Quantum Information Processor," Quantum Information and Computation 5, 515 (2005).
12. Arryx, Inc., BioRyx200.
13. P. J. Rodrigo, R. L. Eriksen, V. R. M. Daria, and J. Gluckstad, "Interactive light-driven and parallel manipulation of inhomogeneous particles," Opt. Express 10, 1550 (2002).
14. P. J. Rodrigo, V. R. Daria, and J. Gluckstad, "Four-dimensional optical manipulation of colloidal particles," Appl. Phys. Lett. 86, 074103 (2005). [CrossRef]
15. J. Leach, K. Wulff, G. Sinclair, P. Jordan, J. Courtial, L. Thomson, G. Gibson, K. Karunwi, J. Cooper, Z. J. Laczik, and M. Padgett, "Interactive approach to optical tweezers control," Appl. Opt. 45, 897 (2005).
16. E. R. Dufresne, G. C. Spalding, M. T. Dearing, S. A. Sheets, and D. G. Grier, "Computer-generated Holographic Optical Tweezer Arrays," Rev. Sci. Instrum. 72, 1810 (2001). [CrossRef]
17. J. Liesener, M. Reicherter, T. Haist, and H. J. Tiziani, "Multi-functional Optical Tweezers Using Computer-Generated Holograms," Opt. Commun. 185, 77 (2000). [CrossRef]
18. J. E. Curtis, B. A. Koss, and D. G. Grier, "Dynamic Holographic Optical Tweezers," Opt. Commun. 207, 169 (2002). [CrossRef]
19. http://www.eng.yale.edu/softmatter.
20. J. C. Crocker and D. G. Grier, "Methods of digital video microscopy for colloidal studies," J. Colloid Interface Sci. 179, 298 (1996). [CrossRef]
21. R. W. Gerchberg and W. O. Saxton, "A practical algorithm for the determination of the phase from image and diffraction plane pictures," Optik 35, 237 (1972).
22. J. E. Curtis, C. H. J. Schmitz, and J. P. Spatz, "Symmetry dependence of holograms for optical trapping," Opt. Lett. 30, 2086 (2005). [CrossRef]
23. P. Y. Chiou, A. T. Ohta, and M. C. Wu, "Massively parallel manipulation of single cells and microparticles using optical images," Nature 435, 370 (2005).
24. M. Reicherter, S. Zwick, T. Haist, C. Kohler, H. Tiziani, and W. Osten, "Fast digital hologram generation and adaptive force measurement in liquid-crystal-display-based holographic tweezers," Appl. Opt. 45, 888 (2006). [CrossRef]

Author Affiliations

Stephen C. Chapin, Vincent Germain, Eric R. Dufresne

Yale University

Multimedia

Cited By

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

Advanced Search

Recent ToC Categories (Beta)

• Jan 14 2010 : OSA wins SPARC Innovator award for Optics Express. Read the press release.
• Jan 14 2010 : The Journal of the Optical Society of Korea is now available in the Optics InfoBase!
• Jan 08 2010 : Optics InfoBase now supports export to Mendeley. Learn more about Mendeley for online citation management and sharing.

More News

• Journal of the Optical Society of Korea Added to OSA’s Optics InfoBase
  Feb 1, 2010 - The Optical Society (OSA) is pleased to announce that Optics... more
• OSA to Launch New Journal: Biomedical Optics Express
  Jan 20, 2010 - The Optical Society (OSA) today announced it is launching a new... more
• Invisibility Visualized
  Nov 12, 2009 - Scientists and curiosity seekers who want to know what a partially or... more