Abstract

Real time, high-speed image stabilization with a retinal tracking scanning laser ophthalmoscope (TSLO) enables new approaches to established diagnostics. Large frequency range (DC to 19 kHz), wide-field (40-deg) stabilized Doppler flowmetry imaging was demonstrated in initial human subject tests. The fundus imaging method is a quasi-confocal line-scanning laser ophthalmoscope (LSLO). The retinal tracking system uses a confocal reflectometer with a closed loop optical servo system to lock onto features in the ocular fundus and automatically re-lock after blinks. By performing a slow scan with the laser line imager, frequency-resolved retinal perfusion and vascular flow images were obtained free of eye motion artifacts. Normal adult subjects and patients were tested with and without mydriasis to characterize flow imaging performance.

© 2004 Optical Society of America

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History
Original Manuscript: August 31, 2004
Revised Manuscript: October 4, 2004
Published: October 18, 2004

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Author Affiliations

Ann Elsner, Robert Webb, Stephen Burns

Harvard Medical School

R. Ferguson, Daniel Hammer

Physical Sciences Inc.

John Weiter

Retinal Specialists of Boston

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