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Optics Express

Optics Express

  • Editor: J. H. Eberly
  • Vol. 1, Iss. 13 — Dec. 22, 1997
  • pp: 424–431

High resolution imaging of in vivo cardiac dynamics using color Doppler optical coherence tomography

Siavash Yazdanfar, Manish D. Kulkarni, and Joseph A. Izatt  »View Author Affiliations


Optics Express, Vol. 1, Issue 13, pp. 424-431 (1997)
http://dx.doi.org/10.1364/OE.1.000424


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Abstract

Color Doppler optical coherence tomography (CDOCT) is a noninvasive technique for simultaneous high spatial resolution (~20 μm) imaging and high velocity resolution (~500 μm/s) imaging flowmetry in living tissues. In this paper, we demonstrate a reconstruction method which overcomes fundamental limitations on Doppler flow mapping associated with both high- and low-speed imaging. This algorithm is successful in retaining the high velocity resolution of CDOCT while eliminating motion artifact caused by slow image acquisition in samples which exhibit repetitive motion. We demonstrate reconstruction of blood flow throughout a beating Xenopus laevis heart and surrounding vasculature using gated CDOCT reconstruction.

© Optical Society of America

OCIS Codes
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(170.3340) Medical optics and biotechnology : Laser Doppler velocimetry
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine

ToC Category:
Focus Issue: Biomedical optics

History
Original Manuscript: October 15, 1997
Revised Manuscript: October 9, 1997
Published: December 22, 1997

Citation
Siavash Yazdanfar, Manish Kulkarni, and Joseph Izatt, "High resolution imaging of in vivo cardiac dynamics using color Doppler optical coherence tomography," Opt. Express 1, 424-431 (1997)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-1-13-424


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References

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