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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 10, Iss. 1 — Jan. 14, 2002
  • pp: 2–14

Analytical model for dual-interfering sources diffuse optical tomography

X. Intes, V. Ntziachristos, and B. Chance  »View Author Affiliations

Optics Express, Vol. 10, Issue 1, pp. 2-14 (2002)

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An analytical model to perform tomographic reconstructions for absorptive inclusions in highly scattering media using dual interfering sources was derived. A perturbation approach within the first order Rytov expansion was used to solve the heterogeneous diffusion equation. Analytical weight functions necessary to solve the inverse problem were obtained. The reconstructions performance was assessed using simulated data of breast-like media after contrast agent enhancement. We further investigated the reconstruction quality as a function of object depth location, modulation frequency and source separation. The ability of the algorithm to resolve multi-objects was also demonstrated.

© Optical Society of America

OCIS Codes
(110.5100) Imaging systems : Phased-array imaging systems
(170.0110) Medical optics and biotechnology : Imaging systems
(170.5270) Medical optics and biotechnology : Photon density waves
(170.5280) Medical optics and biotechnology : Photon migration
(170.6960) Medical optics and biotechnology : Tomography

ToC Category:
Research Papers

Original Manuscript: September 19, 2001
Published: January 14, 2002

Xavier Intes, Vasilis Ntziachristos, and Britton Chance, "Analytical model for dual-interfering sources diffuse optical tomography," Opt. Express 10, 2-14 (2002)

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