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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 10, Iss. 1 — Jan. 14, 2002
  • pp: 35–40

Longitudinal imaging in biological tissues with a single laser shot correlation system

E. Bordenave, E. Abraham, G. Jonusauskas, J. Oberlé, and C. Rullière  »View Author Affiliations


Optics Express, Vol. 10, Issue 1, pp. 35-40 (2002)
http://dx.doi.org/10.1364/OE.10.000035


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Abstract

We demonstrate the potential of a new optical imaging system to directly obtain a longitudinal slice of a biological sample. The system, based on a single-shot optical correlator, operates a time-to-space conversion and an optical time-gating by sum-frequency generation in a nonlinear crystal. Owing to the high speed acquisition of the technique, internal structures of in-vivo tissues can be imaged at video rate. With this apparatus, we recorded longitudinal images of ex vivo mouse ear and in vivo human skin with a depth resolution of approximately 15 μm.

© Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(190.7110) Nonlinear optics : Ultrafast nonlinear optics

ToC Category:
Research Papers

History
Original Manuscript: December 10, 2001
Published: January 14, 2002

Citation
E. Bordenave, Emmanuel Abraham, G. Jonusauskas, J. Oberle, and Claude Rulliere, "Longitudinal imaging in biological tissues with a single laser shot correlation system," Opt. Express 10, 35-40 (2002)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-10-1-35


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References

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