OSA's Digital Library

Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 10, Iss. 4 — Feb. 25, 2002
  • pp: 222–229

Effects of molecular asymmetry of optically active molecules on the polarization properties of multiply scattered light

I. Alex Vitkin, Richard D. Laszlo, and Claire L. Whyman  »View Author Affiliations


Optics Express, Vol. 10, Issue 4, pp. 222-229 (2002)
http://dx.doi.org/10.1364/OE.10.000222


View Full Text Article

Enhanced HTML    Acrobat PDF (151 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

The use of polarized light for investigation of optically turbid systems has generated much recent interest since it has been shown that multiple scattering does not fully scramble the incident polarization states. It is possible under some conditions to measure polarization signals in diffusely scattered light, and use this information to characterize the structure or composition of the turbid medium. Furthermore, the idea of quantitative detection of optically active (chiral) molecules contained in such a system is attractive, particularly in clinical medicine where it may contribute to the development of a non-invasive method of glucose sensing in diabetic patients. This study uses polarization modulation and synchronous detection in the perpendicular and in the exact backscattering orientations to detect scattered light from liquid turbid samples containing varying amounts of L and D (left and right) isomeric forms of a chiral sugar. Polarization preservation increased with chiral concentrations in both orientations. In the perpendicular orientation, the optical rotation of the linearly polarized fraction also increased with the concentration of chiral solute, but in different directions for the two isomeric forms. There was no observed optical rotation in the exact backscattering geometry for either isomer. The presence of the chiral species is thus manifest in both detection directions, but the sense of the chiral asymmetry is not resolvable in retro-reflection. The experiments show that useful information may be extracted from turbid chiral samples using polarized light.

© Optical Society of America

OCIS Codes
(260.2130) Physical optics : Ellipsometry and polarimetry
(290.4210) Scattering : Multiple scattering

ToC Category:
Research Papers

History
Original Manuscript: January 7, 2002
Revised Manuscript: February 21, 2002
Published: February 25, 2002

Citation
I. Vitkin, Richard Laszlo, and Claire Whyman, "Effects of molecular asymmetry of optically active molecules on the polarization properties of multiply scattered light," Opt. Express 10, 222-229 (2002)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-10-4-222


Sort:  Journal  |  Reset  

References

  1. L. D. Barron, Molecular Light Scattering and Optical Activity (Cambridge Press, London, 1982).
  2. M. P. van Albada and A. Lagendijk, ?Observation of weak localization of light in a random medium,? Phys. Rev. Lett. 55, 2692-2695 (1985). [CrossRef]
  3. P. E. Wolf and G. Maret, ?Weak localization and coherent backscattering of photons in disordered media,? Phys. Rev. Lett. 55, 2696-2699 (1985). [CrossRef] [PubMed]
  4. J. M. Schmitt, A. H. Gangjbakhche, and R. F. Bonner, ?Use of polarized light to discriminate short-path photons in multiply scattering medium,? Appl. Opt. 31, 6535-6546 (1992). [CrossRef] [PubMed]
  5. M. P. Silverman, W. Strange, J. Badoz, and I. A. Vitkin, ?Enhanced optical rotation and diminished depolarization in diffusive scattering from a chiral liquid,? Opt. Commun. 132, 410-416 (1996). [CrossRef]
  6. Vitkin and E. Hoskinson, ?Polarization studies in multiply scattering chiral media,? Opt. Eng. 39, 353-362 (2000). [CrossRef]
  7. R. C. N. Studinski and I. A. Vitkin, ?Methodology for examining polarized light interactions with tissues and tissuelike media in the exact backscattering direction,? J. Biomed. Opt. 5, 330-337 (2000). [CrossRef] [PubMed]
  8. X. Wang, G. Yao, and L. H. Wang, ?Monte Carlo model and single-scattering approximation of the propagation of polarized light in turbid media containing glucose,? Appl. Opt. 41, 792-801 (2001). [CrossRef]
  9. Hielscher, J. R. Mourant, and I. J. Bigio, ?Influence of the particle size and concentration on the diffuse backscattering of polarized light from tissue samples and biological cell suspensions,? Appl. Opt. 36, 125-135 (1997). [CrossRef] [PubMed]
  10. M. J. Rakovic and G. W. Kattawar, ?Theoretical analysis of polarization patterns from incoherent backscattering of light,? Appl. Opt. 37, 3333-3338 (1998). [CrossRef]
  11. G. Yao and L. H. Wong, ?Two-dimensional depth-resolved Mueller matrix characterization of biological tissue by optical coherence tomography,? Opt. Lett. 24, 537-539 (1999). [CrossRef]
  12. S. Bartel and A. H. Hielscher, ?Monte Carlo simulations of the diffuse backscattering Mueller matrix for highly scattering media,? Appl. Opt. 39, 1580-1588 (2000). [CrossRef]
  13. H. Hilescher, A. A. Eick, J. R. Mourant, D. Shen, J. P. Freyer, and I. J. Bigio, ?Diffuse backscattering Mueller matrices of highly scattering media,? Opt. Express 1, 441-454 (1997), <a href="http://www.opticsexpress.org/abstract.cfm?URI=OPEX-1-13-441">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-1-13-441</a> [CrossRef]
  14. Ambirajan and D. C. Look, ?A backward Monte Carlo study of the multiple scattering of a polarized light beam,? J. Quant. Spectrosc. Radiat. Transfer 58, 171-192 (1997). [CrossRef]
  15. V. Sankaran, J. T. Walsh, and D. J. Maitland, ?Polarized light propagation through tissue phantoms containing closely packed scatterers,? Opt. Lett. 25, 239-241 (2000). [CrossRef]
  16. V. Sankaran, M. J. Everett, D. J. Maitland, and J. T. Walsh, ?Comparison of polarized light propagation in biological tissues and phantoms,? Opt. Lett. 24, 1046-1048 (1999). [CrossRef]
  17. S. L. Jacques, J. R. Roman, and K. Lee, ?Imaging superficial tissues with polarized light,? Lasers Surg. Med. 26, 199-129 (2000). [CrossRef]
  18. J. McNickols and G. L. Cote, ?Optical glucose sensing in biological fluids: an overview,? J. Biomed. Opt. 5, 5-16 (2000). [CrossRef]
  19. J. C. Kemp, ?Piezo-optical birefringence modulators: new use for a long-known effect,? J. Exp. Theor. Phys. 59, 950-954 (1969).
  20. E. Collett, Polarized Light: Fundamentals and Applications (Marcel Dekker, New York, 1993).
  21. C. Brosseau, Fundamentals of Polarized Light: a Statistical Optics Approach (Wiley, New York, 1998).
  22. K. Hadley and I. A. Vitkin, ?Linear and circular depolarization rates in diffusive scattering from chiral, achiral, and racemic turbid media,? J. Biomed. Optics (submitted Feb 2002). [CrossRef]
  23. A.S. Martinez and R. Maynard, ?Polarization statistics in multiple scattering of light: a Monte Carlo approach,? in: C. M. Souloukis (ed.) Photonic Band Gaps and Localization, 99-114 (Plenum, New York, 1993).
  24. Lakhtakia, Beltrami Fields in Chiral Media (World Scientific Publishing, Singapore, 1994).
  25. D. Bicout, C. Brosseau, A. S. Martinez, and J. M. Schmitt, ?Depolarization of multiply scattered waves by spherical diffusers: influence of size parameter,? Phys. Rev. E 49, 1767-1770 (1994). [CrossRef]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


« Previous Article

OSA is a member of CrossRef.

CrossCheck Deposited