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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 10, Iss. 9 — May. 6, 2002
  • pp: 429–435

Video-rate three-dimensional optical coherence tomography

Markus Laubscher, Mathieu Ducros, Boris Karamata, Theo Lasser, and René Salathé  »View Author Affiliations

Optics Express, Vol. 10, Issue 9, pp. 429-435 (2002)

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Most current optical coherence tomography systems provide two-dimensional cross-sectional or en face images. Successive adjacent images have to be acquired to reconstruct three-dimensional objects, which can be time consuming. Here we demonstrate three-dimensional optical coherence tomography (3D OCT) at video rate. A 58 by 58 smart-pixel detector array was employed. A sample volume of 210x210x80 μm3 (corresponding to 58x58x58 voxels) was imaged at 25 Hz. The longitudinal and transverse resolutions are 3 μm and 9 μm respectively. The sensitivity of the system was 76 dB. Video rate 3D OCT is illustrated by movies of a strand of hair undergoing fast thermal damage.

© 2002 Optical Society of America

OCIS Codes
(110.6880) Imaging systems : Three-dimensional image acquisition
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(170.6900) Medical optics and biotechnology : Three-dimensional microscopy

ToC Category:
Research Papers

Original Manuscript: March 5, 2002
Revised Manuscript: April 8, 2002
Published: May 6, 2002

Markus Laubscher, Mathieu Ducros, Boris Karamata, Theo Lasser, and Rene Salathe, "Video-rate three-dimensional optical coherence tomography," Opt. Express 10, 429-435 (2002)

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  1. M. E. Brezinski and J. G. Fujimoto, "Optical coherence tomography: high-resolution imaging in nontransparent tissue," IEEE J. Selec. Top. Quant. Electron. 5, 1185-1192 (1999) [CrossRef]
  2. A. F. Fercher, "Optical Coherence Tomography," J. Biomed. Opt. 1, 157-173 (1996) [CrossRef] [PubMed]
  3. J. M. Schmitt, "Optical Coherence Tomography (OCT): A Review," IEEE J. Selec. Top. Quant. Electron. 5, 1205-1215 (1999) [CrossRef]
  4. W. Drexler, U. Morgner, F. X. Kartner, C. Pitris, S. A. Boppart, X. D. Li, E. P. Ippen, and J. G. Fujimoto, "In vivo ultrahigh-resolution optical coherence tomography," Opt. Lett. 24, 1221-1223 (1999) [CrossRef]
  5. A. M. Rollins, M. D. Kulkarni, S. Yazdanfar, R. Ung-arunyawee, and J. A. Izatt, "In vivo video rate optical coherence tomography," Opt. Express 3, 219-229 (1998), <a href="http://www.opticsexpress.org/abstract.cfm?URI=OPEX-3-6-219">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-3-6-219</a> [CrossRef] [PubMed]
  6. J. Szydlo, N. Delachenal, R. Giannotti, R. Walti, H. Bleuler, and R. P. Salathe, "Air-turbine driven optical low-coherence reflectometry at 28.6- kHz scan repetition rate," Opt. Commun. 154, 1-4 (1998) [CrossRef]
  7. M. J. Everett, K. Schoenenberger, B. W. Colston, and L. B. Da Silva, "Birefringence characterization of biological tissue by use of optical coherence tomography," Opt. Lett. 23, 228-230 (1998) [CrossRef]
  8. J. F. deBoer, T. E. Milner, M. J. C. vanGemert, and J. S. Nelson, "Two-dimensional birefringence imaging in biological tissue by polarization-sensitive optical coherence tomography," Opt. Lett. 22, 934-936 (1997) [CrossRef]
  9. X. J. Wang, T. E. Milner, and J. S. Nelson, "Characterization of Fluid-Flow Velocity by Optical Doppler Tomography," Opt. Lett. 20, 1337-1339 (1995) [CrossRef] [PubMed]
  10. J. K. Barton, J. A. Izatt, M. D. Kulkarni, S. Yazdanfar, and A. J. Welch, "Three-dimensional reconstruction of blood vessels from in vivo color Doppler optical coherence tomography images," Dermatology 198, 355-361 (1999) [CrossRef]
  11. Y. Pan and D. Farkas, "Non-invasive Imaging of Living Human Skin with Dual-wavelength Optical Coherence Tomography in Two and Three Dimensions," J. Biomed. Opt. 3, 446-455 (1998) [CrossRef] [PubMed]
  12. J. M. Herrmann, M. E. Brezinski, B. E. Bouma, S. A. Boppart, C. Pitris, J. F. Southern, and J. G. Fujimoto, "Two- and three-dimensional high-resolution imaging of the human oviduct with optical coherence tomography," Fertil. Steril. 70, 155-158 (1998) [CrossRef] [PubMed]
  13. A. G. Podoleanu, J. A. Rogers, and D. A. Jackson, "Three dimensional OCT images from retina and skin," Opt. Express 7, 292-298 (2000), <a href="http://www.opticsexpress.org/abstract.cfm?URI=OPEX-7-9-292">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-7-9-292</a> [CrossRef] [PubMed]
  14. B. M. Hoeling, A. D. Fernandez, R. C. Haskell, E. Huang, W. R. Myers, D. C. Petersen, S. E. Ungersma, R. Y. Wang, M. E. Williams, and S. E. Fraser, "An optical coherence microscope for 3-dimensional imaging in developmental biology," Opt. Express 6, 136-146 (2000), Opt. Express <a href=http://www.opticsexpress.org/abstract.cfm?URI=OPEX-6-7-136">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-6-7-136</a> [CrossRef] [PubMed]
  15. E. Beaurepaire, A. C. Boccara, M. Lebec, L. Blanchot, and H. Saint-Jalmes, "Full-field optical coherence microscopy," Opt. Lett. 23, 244-246 (1998) [CrossRef]
  16. A. Knüttel, J. M. Schmitt, and J. R. Knutson, "Low-coherence reflectometry for stationary lateral and depth profiling with acousto-optic deflectors and a CCD camera," Opt. Lett. 19, 302-304 (1994) [CrossRef] [PubMed]
  17. S. Bourquin, P. Seitz, and R. P. Salathé, "Optical coherence topography based on a two-dimensional smart detector array," Opt. Lett. 26, 512-514 (2001) [CrossRef]
  18. S. Bourquin, V. Monterosso, P. Seitz, and R. P. Salathé, "Video rate optical low-coherence reflectometry based on a linear smart detector array," Opt. Lett. 25, 102-104 (2000) [CrossRef]
  19. M. Ducros, M. Laubscher, B. Karamata, S. Bourquin, T. Lasser, and R. P. Salathe, "Parallel optical coherence tomography in scattering samples using a two-dimensional smart-pixel detector array," Opt. Commun. 202, 29-35 (2002) [CrossRef]
  20. J. A. Izatt, M. R. Hee, G. M. Owen, E. A. Swanson, and J. G. Fujimoto, "Optical coherence microscopy in scattering media," Opt. Lett. 19, 590-2 (1994) [CrossRef] [PubMed]
  21. E. A. Swanson, D. Huang, M. R. Hee, J. G. Fujimoto, C. P. Lin, and C. A. Puliafito, "High-speed optical coherence domain reflectometry," Opt. Lett. 17, 151-3 (1992) [CrossRef] [PubMed]
  22. P. Thevenaz and M. Unser, "High-Quality Isosurface Rendering with Exact Gradient," in Proceedings of The 2001 IEEE International Conference on Image Processing (ICIP'01), 1, 854-857 (2001).

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