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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 11, Iss. 16 — Aug. 11, 2003
  • pp: 1844–1855

“Look-Ahead Distance” of a fiber probe used to assist neurosurgery: Phantom and Monte Carlo study

Zhiyu Qian, Sundar S. Victor, Yueqing Gu, Cole A. Giller, and Hanli Liu  »View Author Affiliations

Optics Express, Vol. 11, Issue 16, pp. 1844-1855 (2003)

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A short-separation, optical reflectance probe has been developed to assist the neurosurgeon in functional neurosurgery for accurate localization of the surgical target. Because of the scattering nature of tissue, the optical probe has a “Look Ahead Distance” (LAD), at which the measured optical reflectance starts to “see” or “sense” the underlying brain structure due to the difference in light scattering of tissue. To quantify the LAD, 2-layer laboratory phantoms have been developed to mimic gray and white matter of the brain, and Monte Carlo simulations have been also used to confirm the experimental findings. Based on both the laboratory and simulation results, a quantitative empirical equation is developed to express the LAD as a function of scattering coefficient of the measured tissue for a 400-micron-diameter fiber probe. The quantified LAD of the probe is highly desirable so as to improve the spatial resolution of the probe for better surgery guidance.

© 2003 Optical Society of America

OCIS Codes
(170.1610) Medical optics and biotechnology : Clinical applications
(290.7050) Scattering : Turbid media

ToC Category:
Research Papers

Original Manuscript: April 24, 2003
Revised Manuscript: July 16, 2003
Published: August 11, 2003

Zhiyu Qian, Sundar Victor, Yueqing Gu, Cole Giller, and Hanli Liu, "Look-Ahead Distance of a fiber probe used to assist neurosurgery: Phantom and Monte Carlo study," Opt. Express 11, 1844-1855 (2003)

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