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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 11, Iss. 21 — Oct. 20, 2003
  • pp: 2753–2761

Three-dimensional imaging of the human retina by high-speed optical coherence tomography

Christoph K. Hitzenberger, Peter Trost, Pak-Wai Lo, and Qienyuan Zhou  »View Author Affiliations


Optics Express, Vol. 11, Issue 21, pp. 2753-2761 (2003)
http://dx.doi.org/10.1364/OE.11.002753


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Abstract

Conventional optical coherence tomography is based on A-scans, i.e., the fast scan direction is the z-direction. While this technique has been successfully demonstrated for two-dimensional cross sectional imaging of various tissues, it is rather slow if three-dimensional information is to be obtained. We report on a new technique that combines the transverse scanning approach of a confocal scanning laser ophthalmoscope with the depth sectioning capability of OCT. A stable high-frequency carrier is generated by use of an acousto optic modulator, and high frame rate is obtained by using a resonant scanning mirror for the priority scan (x-direction). Our prototype instrument records 64 transverse images consisting of 256×128 pixels in 1.2 seconds, thus providing the fastest retinal 3D OCT scanning system reported so far. We demonstrate the capabilities of our system by measuring and imaging the fovea and the optic nerve head region of healthy human volunteers in vivo.

© 2003 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(110.6880) Imaging systems : Three-dimensional image acquisition
(170.4470) Medical optics and biotechnology : Ophthalmology

ToC Category:
Research Papers

History
Original Manuscript: September 15, 2003
Revised Manuscript: October 14, 2003
Published: October 20, 2003

Citation
Christoph Hitzenberger, Peter Trost, Pak-Wai Lo, and Qienyuan Zhou, "Three-dimensional imaging of the human retina by high-speed optical coherence tomography," Opt. Express 11, 2753-2761 (2003)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-11-21-2753


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