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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 11, Iss. 24 — Dec. 1, 2003
  • pp: 3290–3297

Ultrahigh resolution real time OCT imaging using a compact femtosecond Nd:Glass laser and nonlinear fiber

S. Bourquin, A. D. Aguirre, I. Hartl, P. Hsiung, T. H. Ko, J. G. Fujimoto, T. A. Birks, W. J. Wadsworth, U. Bünting, and D. Kopf  »View Author Affiliations


Optics Express, Vol. 11, Issue 24, pp. 3290-3297 (2003)
http://dx.doi.org/10.1364/OE.11.003290


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Abstract

Ultrahigh resolution, real time OCT imaging is demonstrated using a compact femtosecond Nd:Glass laser that is spectrally broadened in a high numerical aperture single mode fiber. A reflective grating phase delay scanner enables broad bandwidth, high-speed group delay scanning. We demonstrate in vivo, ultrahigh resolution, real time OCT imaging at 1 µm center wavelength with <5 µm axial resolution in free space (<4 µm in tissue). The light source is robust, portable, and well suited for in vivo imaging studies.

© 2003 Optical Society of America

OCIS Codes
(140.3480) Lasers and laser optics : Lasers, diode-pumped
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(320.0320) Ultrafast optics : Ultrafast optics
(320.7090) Ultrafast optics : Ultrafast lasers

ToC Category:
Research Papers

History
Original Manuscript: October 8, 2003
Revised Manuscript: November 19, 2003
Published: December 1, 2003

Citation
S. Bourquin, A. Aguirre, I. Hartl, P. Hsiung, T. Ko, J. Fujimoto, T. Birks, W. Wadsworth, U. Bünting, and D. Kopf, "Ultrahigh resolution real time OCT imaging using a compact femtosecond Nd:Glass laser and nonlinear fiber," Opt. Express 11, 3290-3297 (2003)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-11-24-3290


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References

  1. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991). [CrossRef] [PubMed]
  2. G. J. Tearney, M. E. Brezinski, B. E. Bouma, S. A. Boppart, C. Pitris, J. F. Southern, and J. G. Fujimoto, "In vivo endoscopic optical biopsy with optical coherence tomography," Science 276, 2037-2039 (1997). [CrossRef] [PubMed]
  3. S. A. Boppart, B. E. Bouma, C. Pitris, J. F. Southern, M. E. Brezinski, and J. G. Fujimoto, "In vivo cellular optical coherence tomography imaging," Nature Medicine 4, 861-865 (1998). [CrossRef] [PubMed]
  4. J. K. Ranka, R. S. Windeler, and A. J. Stentz, "Visible continuum generation in air-silica microstructure optical fibers with anomalous dispersion at 800 nm," Opt. Lett. 25, 25-27 (2000). [CrossRef]
  5. T. A. Birks, W. J. Wadsworth, and P. St. J. Russell, "Supercontinuum generation in tapered fibers," Opt. Lett. 25, 1415-1417 (2000). [CrossRef]
  6. D. L. Marks, A. L. Oldenburg, J. J. Reynolds, S. A. Boppart, �??Study of an ultrahigh-numerical-aperture fiber continuum generation source for optical coherence tomography,�?? Opt. Lett. 27, 2010-2012 (2002). [CrossRef]
  7. I. Hartl, X. D. Li, C. Chudoba, R. Ghanta, T. Ko, J. G. Fujimoto, J. K. Ranka, and R. S. Windeler, "Ultrahigh- resolution optical coherence tomography using continuum generation in an air-silica microstructure optical fiber," Opt. Lett. 26, 608-610 (2001). [CrossRef]
  8. Y. Wang, Y. Zhao, J. S. Nelson, Z. Chen, R. S. Windeler, "Ultrahigh-resolution optical coherence tomography by broadband continuum generation from a photonic crystal fiber," Opt. Lett., 28, 182-184 (2003). [CrossRef] [PubMed]
  9. B. Povazay, K. Bizheva, A. Unterhuber, B. Hermann, H. Sattmann, A. F. Fercher, W. Drexler, A. Apolonski, W. J. Wadsworth, J. C. Knight, P. St. Russell, M. Vetterlein, and E. Scherzer, "Submicrometer axial resolution optical coherence tomography," Opt. Lett. 27, 1800-1802 (2002). [CrossRef]
  10. Y. Wang, J. Stuart Nelson, Z. Chen, B. J. Reiser, R. S. chuck, and R. S. Windeler, "Optimal wavelength for ultrahigh-resolution optical coherence tomography," Opt. Express 11, 1411-1417 (2003), <a href="http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-12-1411">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-12-1411</a> [CrossRef] [PubMed]
  11. F. X. Kärtner, I. D. Jung, and U. Keller, "Soliton mode-locking with saturable absorbers," Special Issue on Ultrafast Electronics, Photonics and Optoelectronics, IEEE J. Sel. Top. Quantum Electron. 2, 540-556 (1996). [CrossRef]
  12. D. Kopf, F. X. Kärtner, K. J. Weingarten, and U. Keller, "Diode-pumped mode-locked Nd:glass lasers with an antiresonant Fabry-Perot saturable absorber," Opt. Lett. 20, 1169-1171 (1995). [CrossRef] [PubMed]
  13. U. Keller, K. J. Weingarten, F. X. Kärtner, D. Kopf, B. Braun, I. D. Jung, R. Fluck, C. Hönninger, N. Matuschek, and J. Aus der Au, "Semiconductor Saturable Absorber Mirrors (SESAM's) for femtosecond to nanosecond pulse generation in solid-state lasers," IEEE J. Sel. Top. Quantum Electron. 2, 435-453 (1996). [CrossRef]
  14. I. Hartl, A. M. Kowalevicz, P.-L. Hsiung, T. H. Ko, T. Schibli, F.X. Kärtner, J. G. Fujimoto, T. A. Birks, W. J. Wadsworth, U. Bünting and D. Kopf., "Ultrahigh resolution optical coherence tomography using novel femtosecond laser sources," in Ultrafast Phenomena XIII, Editors R. D. Miller, M.M. Murnane, N.F. Scherer, A.M. Weiner, Springer Verlag, Berlin Heidelberg 2003, pp. 660-662.
  15. G. J. Tearney, B. E. Bouma, and J. G. Fujimoto, "High-speed phase- and group-delay scanning with a grating- based phase control delay line," Opt. Lett. 22, 1811-1813 (1997). [CrossRef]
  16. R. N. Thurston, J. P. Heritage, A. M. Weiner, and W. J. Tomlinson, "Analysis of picosecond pulse shape synthesis by spectral masking in a grating pulse compressor," IEEE J. Quantum Electron. 22, 682-696 (1986). [CrossRef]
  17. S. Backus, C. G. Durfee III, M. M. Murnane, and H. C. Kapteyn, "High power ultrafast lasers," Review of Scientific Instruments 69, 1207-1223 (1998). [CrossRef]
  18. A. V. Zvyagin and D. D. Sampson, "Achromatic optical phase shifter-modulator," Opt. Lett. 26, 187-189 (2001). [CrossRef]
  19. K. L. Corwin, N. R. Newbury, J. M. Dudley, S. Coen, S. A. Diddams, K. Weber, and R. S. Windeler, "Fundamental Noise Limitations to Supercontinuum Generation in Microstructure Fiber," Phys. Rev. Lett. 90, 113904-1 -4 (2003). [CrossRef] [PubMed]
  20. A. Rollins, J. Izatt, M. Kulkarni, S. Yazdanfar, and R. Ung-arunyawee, "In vivo video rate optical coherence tomography," Opt. Express 3, 219-221 (1998), <a href="http://www.opticsexpress.org/abstract.cfm?URI=OPEX-3-6-219">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-3-6-219</a>. [CrossRef] [PubMed]
  21. A. M. Rollins, and J. A. Izatt, "Optimal interferometer designs for optical coherence tomography," Opt. Lett. 24, 1484-1486 (1999). [CrossRef]

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