OSA's Digital Library

Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 11, Iss. 26 — Dec. 29, 2003
  • pp: 3598–3604

High-speed spectral-domain optical coherence tomography at 1.3 µm wavelength

S. H. Yun, G. J. Tearney, B. E. Bouma, B. H. Park, and J. F. de Boer  »View Author Affiliations


Optics Express, Vol. 11, Issue 26, pp. 3598-3604 (2003)
http://dx.doi.org/10.1364/OE.11.003598


View Full Text Article

Enhanced HTML    Acrobat PDF (295 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

We demonstrate a high-speed spectral domain optical coherence tomography (SD-OCT) system capable of acquiring individual axial scans in 24.4 µs at a rate of 19,000 axial scans per second, using an InGaAs line scan camera and broadband light source centered at 1.31 µm. Sensitivity of >105 dB over a 2-mm depth range was obtained with a free-space axial resolution of 12–14 µm, in agreement with our signal-to-noise ratio predictions. Images of human tissue obtained in vivo with SD-OCT show similar penetration depths to those obtained with state-of-the-art time domain OCT despite the ten-fold higher image acquisition speed. These results demonstrate the potential of 1.3 µm SD-OCT for high-speed and high-sensitivity imaging in patients.

© 2003 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Research Papers

History
Original Manuscript: November 25, 2003
Revised Manuscript: December 10, 2003
Published: December 29, 2003

Citation
S. Yun, G. Tearney, B. Bouma, B. Park, and Johannes de Boer, "High-speed spectral-domain optical coherence tomography at 1.3 μm wavelength," Opt. Express 11, 3598-3604 (2003)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-11-26-3598


Sort:  Journal  |  Reset  

References

  1. E. A. Swanson, D. Huang, M. R. Hee, J. G. Fujimoto, C. P. Lin, and C. A. Puliafito, �??High-speed optical coherence domain reflectometry,�?? Opt. Lett. 17, 151-153 (1992). [CrossRef] [PubMed]
  2. G. J. Tearney, H. Yabushita, S. L. Houser, H. T. Aretz, I. K. Jang, K. Schlendorf, C. R. Kauffman, M. Shishkov, E. F. Halpern, and B. E. Bouma, �??Quantification of macrophage content in atherosclerotic plaques by optical coherence tomography,�?? Circulation 106, 113-119 (2003). [CrossRef]
  3. P. Andretzky, M. W. Lindner, J. M. Hermann, A. Schultz, M. Konzog, F. Kiesewetter, and G. Hausler, �??Optical coherence tomography by spectral radar: dynamic range estimation and in vivo measurements of skin,�?? Proc. SPIE 3567, 78-87 (1998).
  4. M. Wojtkowski, R. Leitgeb, A. Kowalczyk, T. Bajraszewski, and A. F. Fercher, �??In vivo human retinal imaging by Fourier domain optical coherence tomography,�?? J. Biomed. Opt. 7, 457-463 (2002). [CrossRef] [PubMed]
  5. R. Leitgeb, C. K. Hitzenberger, and A. F. Fercher, �??Performance of Fourier domain vs. time domain optical coherence tomography,�?? Opt. Express 11, 889-894 (2003), <a href="http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-8-889">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-8-889</a>. [CrossRef] [PubMed]
  6. J. F. de Boer, B. Cense, B.H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, �??Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography,�?? Opt. Lett. 28, 2067-2069 (2003). [CrossRef] [PubMed]
  7. M. A. Choma, M. V. Sarunic, C. Uang, and J. A. Izatt, �??Sensitivity advantage of swept source and Fourier domain optical coherence tomography,�?? Opt. Express 11, 2183-2189 (2003), <a href="http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-18-2183">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-18-2183</a>. [CrossRef] [PubMed]
  8. S. H. Yun, G. J. Tearney, J. F. de Boer, N. Iftimia, and B. E. Bouma, �??High-speed optical frequency domain imaging,�?? Opt. Express 11, 2953-2963 (2003), <a href="http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-22-2953">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-22-2953</a>. [CrossRef] [PubMed]
  9. S. R. Chinn, E. Swanson, and J. G. Fujimoto, �??Optical coherence tomography using a frequency-tunable optical source,�?? Opt. Lett. 22, 340-342 (1997). [CrossRef] [PubMed]
  10. B. Golubovic, B. E. Bouma, and G. J. Tearney, and J. G. Fujimoto, �??Optical frequency-domain reflectometry using rapid wavelength tuning of a Cr4+:forsterite laser,�?? Opt. Lett. 22, 1704-1706 (1997). [CrossRef]
  11. A. F. Fercher, C. K. Hitzenberger, G. Kamp, and S. Y. El-Zaiat, �??Measurements of intraocular distances by backscattering spectral interferometry,�?? Opt. Comm. 117, 43-48 (1995). [CrossRef]
  12. G. Hausler and M. W. Lindner, �??Coherence radar and spectral radar - new tools for dermatological diagnosis,�?? J. Biomed. Opt. 3, 21-31 (1998). [CrossRef]
  13. M. Wojtkowski, A. Kowalczyk, R. Leitgeb, and A. F. Fercher, �??Full range complex spectral optical coherence tomography technique in eye imaging,�?? Opt. Lett. 27, 1415-1417 (2002). [CrossRef]
  14. M. Wojtkowski, T. Bajraszewski, P. Targowski, and A. Kowalczyk, �??Real time in vivo imaging by high-speed spectral optical coherence tomography,�?? Opt. Lett. 28, 1745-1747 (2003). [CrossRef] [PubMed]
  15. N. Nassif, B. Cense, B. H. Park, S. H. Yun, T. C. Chen, B. E. Bouma, G. J. Tearney, J. F. de Boer, �??In-vivo human retinal imaging by ultra high-speed spectral domain optical coherence tomography,�?? Opt. Lett. (in press)
  16. B. E. Bouma and G. J. Tearney, �??Clinical imaging with optical coherence tomography,�?? Acad. Radiol. 9, 942-953 (2002). [CrossRef] [PubMed]
  17. W. V. Sorin and D. M. Baney, �??A simple intensity noise reduction technique for optical low-coherence reflectometry,�?? IEEE Photon. Technol. Lett. 4, 1404-1406 (1994). [CrossRef]
  18. C. Dorrer, N. Belabas, J-P Likforman, and M. Joffre, �??Spectral resolution and sampling issues in Fourier-transform spectral interferometry,�?? J. Opt. Soc. Am. B 17, 1795-1802 (2000). [CrossRef]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

Figures

Fig. 1. Fig. 2. Fig. 3.
 
Fig. 4.
 

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited