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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 11, Iss. 7 — Apr. 7, 2003
  • pp: 794–809

High speed, wide velocity dynamic range Doppler optical coherence tomography (Part I): System design, signal processing, and performance

Victor X.D. Yang, Maggie L. Gordon, Bing Qi, Julius Pekar, Stuart Lo, Emily Seng-Yue, Alvin Mok, Brian C. Wilson, and I. Alex Vitkin  »View Author Affiliations

Optics Express, Vol. 11, Issue 7, pp. 794-809 (2003)

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Improvements in real-time Doppler optical coherence tomography (DOCT), acquiring up to 32 frames per second at 250×512 pixels per image, are reported using signal processing techniques commonly employed in Doppler ultrasound imaging. The ability to measure a wide range of flow velocities, ranging from less than 20 µm/s to more than 10 cm/s, is demonstrated using an 1.3 µm DOCT system with flow phantoms in steady and pulsatile flow conditions. Based on full implementation of a coherent demodulator, four different modes of flow visualization are demonstrated: color Doppler, velocity variance, Doppler spectrum, and power Doppler. The performance of the former two, which are computationally suitable for real-time imaging, are analyzed in detail under various signal-to-noise and frame-rate conditions. The results serve as a guideline for choosing appropriate imaging parameters for detecting in vivo blood flow.

© 2003 Optical Society of America

OCIS Codes
(100.6950) Image processing : Tomographic image processing
(110.4500) Imaging systems : Optical coherence tomography
(170.1650) Medical optics and biotechnology : Coherence imaging
(170.3880) Medical optics and biotechnology : Medical and biological imaging

ToC Category:
Research Papers

Original Manuscript: February 6, 2003
Revised Manuscript: March 30, 2003
Published: April 7, 2003

Victor Yang, Maggie Gordon, Bing Qi, Julius Pekar, Stuart Lo, Emily Seng-Yue, Alvin Mok, Brian Wilson, and I. Vitkin, "High speed, wide velocity dynamic range Doppler optical coherence tomography (Part I): System design, signal processing, and performance," Opt. Express 11, 794-809 (2003)

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