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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 12, Iss. 18 — Sep. 6, 2004
  • pp: 4275–4281

Mini-invasive corneal surgery and imaging with femtosecond lasers

Meng Han, Günter Giese, Leander Zickler, Hui Sun, and Josef F. Bille  »View Author Affiliations

Optics Express, Vol. 12, Issue 18, pp. 4275-4281 (2004)

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Based on the transparency of corneal tissue and on laser plasma mediated non-thermal tissue ablation, near infrared femtosecond lasers are promising tools for minimally invasive intrastromal refractive surgery. Femtosecond lasers also enable novel nonlinear optical imaging methods like second harmonic corneal imaging. The microscopic effects of femtosecond laser intrastromal surgery were successfully visualized by using second harmonic corneal imaging with diffraction limited resolution, strong imaging contrast and large sensing depth, without requiring tissue fixation or sectioning. The performance of femtosecond laser intrastromal surgery proved to be precise, repeatable and predictable. It might be possible to integrate both surgical and probing functions into a single femtosecond laser system.

© 2004 Optical Society of America

OCIS Codes
(140.7090) Lasers and laser optics : Ultrafast lasers
(170.4470) Medical optics and biotechnology : Ophthalmology
(180.5810) Microscopy : Scanning microscopy

ToC Category:
Research Papers

Original Manuscript: June 18, 2004
Revised Manuscript: August 25, 2004
Published: September 6, 2004

Meng Han, Günter Giese, Leander Zickler, Hui Sun, and Josef Bille, "Mini-invasive corneal surgery and imaging with femtosecond lasers," Opt. Express 12, 4275-4281 (2004)

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