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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 12, Iss. 19 — Sep. 20, 2004
  • pp: 4558–4572

OCT-based arterial elastography: robust estimation exploiting tissue biomechanics

R.C. Chan, A.H. Chau, W.C. Karl, S. Nadkarni, A.S. Khalil, N. Iftimia, M. Shishkov, G.J. Tearney, M.R. Kaazempur-Mofrad, and B.E. Bouma  »View Author Affiliations

Optics Express, Vol. 12, Issue 19, pp. 4558-4572 (2004)

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We present a novel multi-resolution variational framework for vascular optical coherence elastography (OCE). This method exploits prior information about arterial wall biomechanics to produce robust estimates of tissue velocity and strain, reducing the sensitivity of conventional tracking methods to both noise- and strain-induced signal decorrelation. The velocity and strain estimation performance of this new estimator is demonstrated in simulated OCT image sequences and in benchtop OCT scanning of a vascular tissue sample.

© 2004 Optical Society of America

OCIS Codes
(100.2960) Image processing : Image analysis
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Research Papers

Original Manuscript: June 25, 2004
Revised Manuscript: August 25, 2004
Published: September 20, 2004

R. Chan, A. Chau, W. Karl, S. Nadkarni, A. Khalil, N. Iftimia, M. Shishkov, G. Tearney, M. Kaazempur-Mofrad, and B. Bouma, "OCT-based arterial elastography: robust estimation exploiting tissue biomechanics," Opt. Express 12, 4558-4572 (2004)

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