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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 13, Iss. 19 — Sep. 19, 2005
  • pp: 7449–7457

In vivo blood flow imaging by a swept laser source based Fourier domain optical Doppler tomography

Jun Zhang and Zhongping Chen  »View Author Affiliations


Optics Express, Vol. 13, Issue 19, pp. 7449-7457 (2005)
http://dx.doi.org/10.1364/OPEX.13.007449


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Abstract

A swept source based Fourier domain optical Doppler tomography (FDODT) system was developed. The technique is based on a phase-resolved method where phase information was retrieved from the reconstructed complex fringe signals. The aliasing effects and artifacts caused by lateral scanning and sample movement were removed with a signal processing technique. The standard deviation of the phase shift of the system was reduced from 49 to 1.8 degrees with the signal processing method employed. Structural, Doppler and Doppler variance images of fluid flow through glass channels were quantified, and blood flow through vessels of chick chorioallantoic membrane (CAM) was demonstrated in vivo

© 2005 Optical Society of America

OCIS Codes
(070.2590) Fourier optics and signal processing : ABCD transforms
(170.3340) Medical optics and biotechnology : Laser Doppler velocimetry
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Research Papers

History
Original Manuscript: July 15, 2005
Revised Manuscript: September 2, 2005
Published: September 19, 2005

Citation
Jun Zhang and Zhongping Chen, "In vivo blood flow imaging by a swept laser source based Fourier domain optical Doppler tomography," Opt. Express 13, 7449-7457 (2005)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-13-19-7449


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