Laser-activated shape memory polymer intravascular thrombectomy device
Optics Express, Vol. 13, Issue 20, pp. 8204-8213 (2005)
http://dx.doi.org/10.1364/OPEX.13.008204
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Abstract
A blood clot (thrombus) that becomes lodged in the arterial network supplying the brain can cause an ischemic stroke, depriving the brain of oxygen and often resulting in permanent disability. As an alternative to conventional clot-dissolving drug treatment, we are developing an intravascular laser-activated therapeutic device using shape memory polymer (SMP) to mechanically retrieve the thrombus and restore blood flow to the brain. Thermal imaging and computer simulation were used to characterize the optical and photothermal behavior of the SMP microactuator. Deployment of the SMP device in an in vitro thrombotic vascular occlusion model demonstrated the clinical treatment concept.
© 2005 Optical Society of America
OCIS Codes
(060.2310) Fiber optics and optical communications : Fiber optics
(140.2020) Lasers and laser optics : Diode lasers
(160.5470) Materials : Polymers
ToC Category:
Research Papers
History
Original Manuscript: August 15, 2005
Revised Manuscript: September 22, 2005
Published: October 3, 2005
Citation
Ward Small IV, Thomas Wilson, William Benett, Jeffrey Loge, and Duncan Maitland, "Laser-activated shape memory polymer intravascular thrombectomy device," Opt. Express 13, 8204-8213 (2005)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-13-20-8204
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