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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 13, Iss. 26 — Dec. 26, 2005
  • pp: 10652–10664

Three-dimensional and high-speed swept-source optical coherence tomography for in vivo investigation of human anterior eye segments

Yoshiaki Yasuno, Violeta Dimitrova Madjarova, Shuichi Makita, Masahiro Akiba, Atsushi Morosawa, Changho Chong, Toru Sakai, Kin-Pui Chan, Masahide Itoh, and Toyohiko Yatagai  »View Author Affiliations


Optics Express, Vol. 13, Issue 26, pp. 10652-10664 (2005)
http://dx.doi.org/10.1364/OPEX.13.010652


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Abstract

A two- and three-dimensional swept source optical coherence tomography (SS-OCT) system, which uses a ready-to-ship scanning light source, is demonstrated. The light source has a center wavelength of 1.31 μm, -3 dB wavelength range of 110 nm, scanning rate of 20 KHz, and high linearity in frequency scanning. This paper presents a simple calibration method using a fringe analysis technique for spectral rescaling. This SS-OCT system is capable of realtime display of two-dimensional OCT and can obtain three-dimensional OCT with a measurement time of 2 s. In vivo human anterior eye segments are investigated two- and three-dimensionally. The system sensitivity is experimentally determined to be 112 dB. The three-dimensional OCT volumes reveal the structures of the anterior eye segments, which are difficult to observe in two-dimensional OCT images. A two dimensional tomographic movie shows a dynamic motion of a human iris.

© 2005 Optical Society of America

OCIS Codes
(100.2650) Image processing : Fringe analysis
(110.4500) Imaging systems : Optical coherence tomography
(110.6880) Imaging systems : Three-dimensional image acquisition
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Research Papers

Virtual Issues
Vol. 1, Iss. 1 Virtual Journal for Biomedical Optics

Citation
Yoshiaki Yasuno, Violeta Dimitrova Madjarova, Shuichi Makita, Masahiro Akiba, Atsushi Morosawa, Changho Chong, Toru Sakai, Kin-Pui Chan, Masahide Itoh, and Toyohiko Yatagai, "Three-dimensional and high-speed swept-source optical coherence tomography for in vivo investigation of human anterior eye segments," Opt. Express 13, 10652-10664 (2005)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-13-26-10652


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