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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 14, Iss. 1 — Jan. 9, 2006
  • pp: 260–269

Analysis of the influence of spherical aberration from focusing through a dielectric slab in quantitative nonlinear optical susceptibility measurements using third-harmonic generation

Rajesh S. Pillai, G.J. Brakenhoff, and M. Müller  »View Author Affiliations


Optics Express, Vol. 14, Issue 1, pp. 260-269 (2006)
http://dx.doi.org/10.1364/OPEX.14.000260


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Abstract

The third-order nonlinear susceptibility (χ(3)) can be measured quantitatively using third-harmonic generation (THG) from two different interfaces. For the first time it is demonstrated both in experiments and theory that the magnitude of the THG signals from the two interfaces is not only determined by material properties (refractive index and χ(3)), but also by optical aberrations. It is found that this method of χ(3) determination can be applied without additional correction factors only for focusing conditions with a numerical aperture (NA) ≤ 0.35. The implications for general application of THG in three-dimensional microscopy are discussed.

© 2006 Optical Society of America

OCIS Codes
(080.1010) Geometric optics : Aberrations (global)
(180.6900) Microscopy : Three-dimensional microscopy
(190.4160) Nonlinear optics : Multiharmonic generation
(190.4410) Nonlinear optics : Nonlinear optics, parametric processes
(190.4720) Nonlinear optics : Optical nonlinearities of condensed matter

ToC Category:
Nonlinear Optics

Virtual Issues
Vol. 1, Iss. 2 Virtual Journal for Biomedical Optics

Citation
Rajesh S. Pillai, G. J. Brakenhoff, and M. Müller, "Analysis of the influence of spherical aberration from focusing through a dielectric slab in quantitative nonlinear optical susceptibility measurements using third-harmonic generation," Opt. Express 14, 260-269 (2006)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-14-1-260


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References

  1. Y. Barad, H. Eisenberg, M. Horowitz, Y. Silberberg, "Nonlinear Scanning Laser Microscopy by Third Harmonic Generation," Appl. Phys. Lett. 70, 922-924 (1997). [CrossRef]
  2. M. Müller, J. Squier, K. R. Wilson and G. J. Brakenhoff, "3D Microscopy of transparent objects using third-harmonic generation," J. Microsc. 191, 266-274 (1998). [CrossRef] [PubMed]
  3. J. F. Ward, G. H. C. New, "Optical Third Harmonic Generation in Gases by a Focused Laser Beam," Phys. Rev. 185, 57-72 (1969). [CrossRef]
  4. R. W. Boyd, Nonlinear Optics (Academic Press, Inc., New York, 1992).
  5. M. Born, E. Wolf, Principles of Optics (Pergamon Press, Oxford, 1993).
  6. J. F. Reintjes, Nonlinear Optical Parametric Processes in Liquids and Gases (Academic Press, Inc., Orlando, 1984).
  7. J. A. Squier, M. Müller, G. J. Brakenhoff and K. R. Wilson, "Third Harmonic Generation Microscopy," Opt. Express 3, 315-324 (1998). [CrossRef] [PubMed]
  8. J. A. Squier, M. Müller, "Third - Harmonic Generation Imaging of laser - induced breakdown in glass," Appl. Opt. 38, 5789-5794 (1999). [CrossRef]
  9. D. Yelin, Y. Silberberg, "Laser scanning third-harmonic-generation microscopy in biology," Opt. Express 5, 169-175 (1999). [CrossRef] [PubMed]
  10. C.-K. Sun, S.-W. Chu, S.-P. Tai, S. Keller, U.K. Mishra, S.P. DenBaars, "Scanning second-harmonic/third-harmonic generation microscopy of gallium nitride," Appl. Phys. Lett. 77, 2331-2333 (2000). [CrossRef]
  11. L. Canioni, S. Rivet, L. Sarger, R. Barille, P. Vacher, and P. Voisin, "Imaging of Ca2+ intracellular dynamics with a third-harmonic generation microscope," Opt. Lett. 26, 515-517 (2001). [CrossRef]
  12. D. Oron, E. Tal and Y. Silberberg, "Depth-resolved multiphoton polarisation microscopy by third-harmonic generation," Opt. Lett. 28, 2315-2317 (2003). [CrossRef] [PubMed]
  13. D. Yelin, Y. Silberberg, Y. Barad and J. S. Patel, "Depth-resolved imaging of nematic liquid crystals by third-harmonic microscopy," Appl. Phys. Lett. 74, 3107-3109 (1999). [CrossRef]
  14. D. Débarre, W. Supatto, E. Farge, B. Moulia, M-C. Schanne-Klein, E. Beaurepaire, "Velocimetric third-harmonic generation microscopy: micrometer-scale quantification of morphogenetic movements in unstained embryos," Opt. Lett. 29, 2881-2883 (2004). [CrossRef]
  15. S.-W. Chu, Szu-Yu Chen, Tsung-Han Tsai, Tzu-Ming Liu, Cheng-Yung Lin, Huai-Jen Tsai, and Chi-Kuang Sun, "In vivo developmental biology study using noninvasive multi-harmonic generation microscopy," Opt. Express 11, 3093-3099 (2003). [CrossRef] [PubMed]
  16. W. Supatto, D. Débarre, B. Moulia, E. Brouzés, J-L. Martin, E. Farge, E. Beaurepaire, "In vivo modulation of morphogenetic movements in Drosophila embryos with femtosecond laser pulses," PNAS 102, 1047-1052 (2005). [CrossRef] [PubMed]
  17. S. Hell, G. Reiner, C. Cremer, E.H.K. Stelzer, "Aberrations in confocal fluorescence microscopy induced by mismatches in refractive index," J. Microsc. 169, 391-405 (1993). [CrossRef]
  18. C. J. R. Sheppard, C.J. Cogswell, "Effects of aberrating layers and tube length on confocal imaging properties," Optik 87, 34-38 (1991).
  19. R. Barille, L. Canioni, L. Sarger, and G. Rivoire, "Nonlinearity measurements of thin films by third-harmonic-generation microscopy," Phys. Rev. E 66 (2002). [CrossRef]
  20. V. Shcheslavskiy, G. Petrov, and V. V. Yakovlev, "Nonlinear optical susceptibility measurements of solutions using third-harmonic generation on the interface," Appl. Phys. Lett. 82, 3982-3984 (2003). [CrossRef]
  21. V. Shcheslavskiy, G. I. Petrov, S. Saltiel, and V. V. Yakovlev, "Quantitative characterization of aqueous solutions probed by the third-harmonic generation microscopy," J. Struct. Biol. 147, 42-49 (2004). [CrossRef] [PubMed]
  22. J. M. Schins, T. Schrama, J. Squier, G. J. Brakenhoff, M. Müller, "Determination of material properties by use of third-harmonic generation microscopy," J. Opt. Soc. Am. B 19, 1627-1634 (2002). [CrossRef]
  23. J. X. Cheng, and X. S. Xie, "Green's function formulation for third-harmonic generation microscopy," J. Opt. Soc. Am. B 19, 1604-1610 (2002). [CrossRef]
  24. F. Kajzar, J. Messier, "Third-harmonic generation in liquids," Phys. Rev. A 32, 2352-2363 (1985). [CrossRef] [PubMed]
  25. I. Z. Kozma, P. Krok, E. Riedle, "Direct measurement of the group-velocity mismatch and derivation of the refractive-index dispersion for a variety of solvents in the ultraviolet," J. Opt. Soc. Am. B 22, 1479-1485 (2005). [CrossRef]
  26. G. R. Meredith, B. Buchalter, and C. Hanzlik, "Third-order susceptibility determination by third harmonic generation. II," J. Chem. Phys. 78, 1543-1551 (1983). [CrossRef]

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