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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 14, Iss. 1 — Jan. 9, 2006
  • pp: 405–414

Interferometric optical detection and tracking of very small gold nanoparticles at a water-glass interface

Volker Jacobsen, Patrick Stoller, Christian Brunner, Viola Vogel, and Vahid Sandoghdar  »View Author Affiliations

Optics Express, Vol. 14, Issue 1, pp. 405-414 (2006)

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We use an interferometric detection scheme to directly detect single gold nanoparticles with a diameter as small as 5 nm in an aqueous environment. We demonstrate both confocal and wide-field detection of nanoparticles and study signal strength as a function of particle size. Furthermore, we demonstrate a detection speed up to 2 μs. We also show that gold nanoparticles can be readily distinguished from background scatterers by exploiting the wavelength dependence of their plasmon resonances. Our studies pave the way for the application of this detection scheme for particle tracking in biological systems.

© 2006 Optical Society of America

OCIS Codes
(170.6920) Medical optics and biotechnology : Time-resolved imaging
(260.3910) Physical optics : Metal optics
(290.5850) Scattering : Scattering, particles

ToC Category:

Virtual Issues
Vol. 1, Iss. 2 Virtual Journal for Biomedical Optics

Volker Jacobsen, Patrick Stoller, Christian Brunner, Viola Vogel, and Vahid Sandoghdar, "Interferometric optical detection and tracking of very small gold nanoparticles at a water-glass interface," Opt. Express 14, 405-414 (2006)

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