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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 14, Iss. 12 — Jun. 12, 2006
  • pp: 5755–5764

Nanoparticle size analysis with relaxation of induced grating by dielectrophoresis

Yukihisa Wada, Shinichiro Totoki, Masayuki Watanabe, Naoji Moriya, Yoshio Tsunazawa, and Shimaoka Haruo  »View Author Affiliations

Optics Express, Vol. 14, Issue 12, pp. 5755-5764 (2006)

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We propose an alternative approach to the use of dynamic light scattering (DLS) for the analysis of particle sizes ranging from 5 nm to 100 nm. This approach employs a combination of 1) diffusion, 2) density grating, and 3) dielectrophoresis (DEP), and measures the diffusion coefficient from the decay rate of the diffracted light intensity in the relaxation process of particle density modulation generated by DEP. Both the experiments and the theoretical analysis confirm the reliable determination of particle size independently of the refractive index. The new method records a decay signal directly without an autocorrelator and is expected to have a less extreme sensitivity dependence on particle size than DLS.

© 2006 Optical Society of America

OCIS Codes
(290.1990) Scattering : Diffusion
(350.4990) Other areas of optics : Particles

ToC Category:

Original Manuscript: January 27, 2006
Revised Manuscript: May 12, 2006
Manuscript Accepted: May 16, 2006
Published: June 12, 2006

Virtual Issues
Vol. 1, Iss. 7 Virtual Journal for Biomedical Optics

Yukihisa Wada, Shinichiro Totoki, Masayuki Watanabe, Naoji Moriya, Yoshio Tsunazawa, and Haruo Shimaoka, "Nanoparticle size analysis with relaxation of induced grating by dielectrophoresis," Opt. Express 14, 5755-5764 (2006)

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  1. ISO Reference, Particle size analysis -Laser diffraction methods-Part 1, ISO 13320-1 (1999).
  2. M. Kerker, The scattering of light, (Academic, New York, 1969), pp. 31-39.
  3. H. G. Barth and R. B. Flippen, "Particle size analysis," Anal. Chem. 67, 257R-272R (1995). [CrossRef]
  4. C. F. Bohren and D. R. Huffman, Absorption and Scattering of Light by Small Particles (John Wiley & Sons, 1983).
  5. ISO Reference, Particle size analysis - Photon correlation spectroscopy, ISO 13321 (1996).
  6. B. J. Berne and R. Pecora, Dynamic Light Scattering With Application to Chemistry, Biology, and Physics (General Publishing Company, Toronto, 1976).
  7. C. S. Johnson, Jr. and D. A. Gabriel, Laser Light Scattering, (Dover, New York, 1994).
  8. H. A. Pohl, Dielectrophoresis, (Cambridge University Press, 1978).
  9. J. Voldman, R. A. Braff, M. Toner, M. L. Gray, and M. A. Schmidt, "Holding forces single-particle dielectrophoretic traps," Biophys. J. 80, 531-541 (2001). [CrossRef] [PubMed]
  10. M. Washizu, S. Suzuki, O. Kurosawa, T. Nishizaka, T. Shinohara, "Molecular dielectrophoresis of biopolymers," IEEE Trans. Ind. Appl. 30, 835-843 (1994). [CrossRef]
  11. H. Watarai, T. Sakamoto, and S. Tsukahara, "In situ measurement of dielectrophoretic mobility of single polystyrene microparticles," Langmuir 13, 2417-2420 (1997). [CrossRef]
  12. M. Terajima, "Translational diffusion of intermediate species in solutions," Res. Chem. Intermed. 23, 853-901 (1997). [CrossRef]
  13. For example, see E. Hecht, Optics fourth edition, (Addison Wesley, San Francisco 2002) pp 449-457.
  14. D. E. Koppel, "Analysis of macromolecular polydispersity in intensity correlation Spectroscopy: The method of cumulants," J. Chem. Phys. 57, 4814-4820 (1972). [CrossRef]
  15. R. Finsy, N. De Jaeger, R. Sneyers, and E. Gelade, "Particle sizing by Photon Correlation Spectroscopy. Part III: Mono and bimodal distributions and data analysis," Part. Part. Syst. Charact. 9, 125-137 (1992). [CrossRef]
  16. R. Finsy, L. Deriemaeker, N. De Jaeger, R. Sneyers, J. Vanderdeelen, P. Van der Meeren, H. Demeyere, J. Stone-Masui, A. Haestier, J. Clauwaert, W. De Wispelaere, P. Gillioen, S. Steyfkens, and E. Gelade, "Particle sizing by photon correlation Spectroscopy. Part IV: Resolution of bimodals and comparison with other particle sizing methods," Part. Part. Syst. Charact. 10, 118-128 (1993). [CrossRef]
  17. E. R. Pike and B. McNally, "Theory and design of photon correlation and light-scattering experiments, "Appl. Opt. 36, 7531-7538 (1997). [CrossRef]

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