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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 14, Iss. 15 — Jul. 24, 2006
  • pp: 6739–6748

Pulsed illumination spectral-domain optical coherence tomography for human retinal imaging

Jang-Woo You, Teresa C. Chen, Mircea Mujat, B. Hyle Park, and Johannes F. de Boer  »View Author Affiliations

Optics Express, Vol. 14, Issue 15, pp. 6739-6748 (2006)

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We present pulsed illumination spectral-domain optical coherence tomography (SD-OCT) for in vivo human retinal imaging. We analyze the signal-to-noise (SNR) for continuous wave (CW) and pulsed illumination SD-OCT. The lateral beam scan motion is responsible for a SNR drop due to lateral scanning induced interference fringe washout. Pulsed illumination can reduce the SNR drop by shorter sample illumination time during the integration time of a camera. First, we demonstrate the SNR benefit of pulsed illumination over CW as function of lateral scan speed for a paper sample. Finally, we show better SNR in retinal images of a normal subject with pulsed illumination SD-OCT over CW at high lateral scanning speed.

© 2006 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: April 7, 2006
Revised Manuscript: June 16, 2006
Manuscript Accepted: July 14, 2006
Published: July 24, 2006

Virtual Issues
Vol. 1, Iss. 8 Virtual Journal for Biomedical Optics

Jang-Woo You, Teresa C. Chen, Mircea Mujat, B. Hyle Park, and Johannes F. de Boer, "Pulsed illumination spectral-domain optical coherence tomography for human retinal imaging," Opt. Express 14, 6739-6748 (2006)

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