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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 14, Iss. 17 — Aug. 21, 2006
  • pp: 7821–7840

Optical coherence angiography

Shuichi Makita, Youngjoo Hong, Masahiro Yamanari, Toyohiko Yatagai, and Yoshiaki Yasuno  »View Author Affiliations

Optics Express, Vol. 14, Issue 17, pp. 7821-7840 (2006)

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Noninvasive angiography is demonstrated for the in vivo human eye. Three-dimensional flow imaging has been performed with high-speed spectral-domain optical coherence tomography. Sample motion is compensated by two algorithms. Axial motion between adjacent A-lines within one OCT image is compensated by the Doppler shift due to bulk sample motion. Axial displacements between neighboring images are compensated by a correlation-based algorithm. Three-dimensional vasculature of ocular vessels has been visualized. By integrating volume sets of flow images, two-dimensional images of blood vessels are obtained. Retinal and choroidal blood vessel images are simultaneously obtained by separating the volume set into retinal part and choroidal parts. These are corresponding to fluorescein angiogram and indocyanine angiogram.

© 2006 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(110.6880) Imaging systems : Three-dimensional image acquisition
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: June 16, 2006
Revised Manuscript: August 1, 2006
Manuscript Accepted: August 5, 2006
Published: August 21, 2006

Virtual Issues
Vol. 1, Iss. 9 Virtual Journal for Biomedical Optics

Shuichi Makita, Youngjoo Hong, Masahiro Yamanari, Toyohiko Yatagai, and Yoshiaki Yasuno, "Optical coherence angiography," Opt. Express 14, 7821-7840 (2006)

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