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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 14, Iss. 19 — Sep. 18, 2006
  • pp: 8613–8621

Freeform multiphoton excited microfabrication for biological applications using a rapid prototyping CAD-based approach

Lawrence P. Cunningham, Matthew P. Veilleux, and Paul J. Campagnola  »View Author Affiliations

Optics Express, Vol. 14, Issue 19, pp. 8613-8621 (2006)

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Multiphoton excited polymerization has attracted increasing attention as a powerful 3 dimensional nano/microfabrication tool. The nonlinear excitation confines the fabrication region to the focal volume allowing the potential to achieve freeform fabrication with submicron capabilities. We report the adaptation and use of a computer aided design (CAD) approach, based on rapid prototyping software, which exploits this potential for fabricating with protein and polymers in biologically compatible aqueous environments. 3D structures are drawn in the STL format creating a solid model that can be sliced, where the individual sections are then serially fabricated without overwriting previous layers. The method is shown for potential biological applications including microfluidics, cell entrapment, and tissue engineering

© 2006 Optical Society of America

OCIS Codes
(120.4610) Instrumentation, measurement, and metrology : Optical fabrication
(180.6900) Microscopy : Three-dimensional microscopy
(190.4180) Nonlinear optics : Multiphoton processes
(220.4000) Optical design and fabrication : Microstructure fabrication
(350.3450) Other areas of optics : Laser-induced chemistry

ToC Category:
Instrumentation, Measurement, and Metrology

Original Manuscript: April 28, 2006
Revised Manuscript: July 19, 2006
Manuscript Accepted: August 11, 2006
Published: September 18, 2006

Virtual Issues
Vol. 1, Iss. 10 Virtual Journal for Biomedical Optics

Lawrence P. Cunningham, Matthew P. Veilleux, and Paul J. Campagnola, "Freeform multiphoton excited microfabrication for biological applications using a rapid prototyping CAD-based approach," Opt. Express 14, 8613-8621 (2006)

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