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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 14, Iss. 6 — Mar. 20, 2006
  • pp: 2211–2219

Multimodal near infrared spectral imaging as an exploratory tool for dysplastic esophageal lesion identification

Chad A. Lieber, Shiro Urayama, Nazir Rahim, Raymond Tu, Ramez Saroufeem, Boris Reubner, and Stavros G. Demos  »View Author Affiliations


Optics Express, Vol. 14, Issue 6, pp. 2211-2219 (2006)
http://dx.doi.org/10.1364/OE.14.002211


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Abstract

We explore nine different combinations of fluorescence, light scattering, and polarization spectral imaging approaches in the near-infrared spectral region toward the diagnosis of pathologic and normal esophageal lesions. The combinations of all the imaging techniques were evaluated for maximal sensitivity and specificity. The results suggest that this multimodal approach is capable of highly accurate detection of the presence of pathologic tissue.

© 2006 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: November 22, 2005
Revised Manuscript: March 6, 2006
Manuscript Accepted: March 8, 2006
Published: March 20, 2006

Virtual Issues
Vol. 1, Iss. 4 Virtual Journal for Biomedical Optics

Citation
Chad A. Lieber, Shiro Urayama, Nazir Rahim, Raymond Tu, Ramez Saroufeem, Boris Reubner, and Stavros G. Demos, "Multimodal near infrared spectral imaging as an exploratory tool for dysplastic esophageal lesion identification," Opt. Express 14, 2211-2219 (2006)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-14-6-2211


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