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Optics Express

Optics Express

  • Editor: Michael Duncan
  • Vol. 14, Iss. 8 — Apr. 17, 2006
  • pp: 3354–3367

Adaptive optics scanning laser ophthalmoscope for stabilized retinal imaging

Daniel X. Hammer, R. Daniel Ferguson, Chad E. Bigelow, Nicusor V. Iftimia, Teoman E. Ustun, and Stephen A. Burns  »View Author Affiliations

Optics Express, Vol. 14, Issue 8, pp. 3354-3367 (2006)

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A retinal imaging instrument that integrates adaptive optics (AO), scanning laser ophthalmoscopy (SLO), and retinal tracking components was built and tested. The system uses a Hartmann-Shack wave-front sensor (HS-WS) and MEMS-based deformable mirror (DM) for AO-correction of high-resolution, confocal SLO images. The system includes a wide-field line-scanning laser ophthalmoscope for easy orientation of the high-magnification SLO raster. The AO system corrected ocular aberrations to <0.1 μm RMS wave-front error. An active retinal tracking with custom processing board sensed and corrected eye motion with a bandwidth exceeding 1 kHz. We demonstrate tracking accuracy down to 6 μm RMS for some subjects (typically performance: 10–15 μm RMS). The system has the potential to become an important tool to clinicians and researchers for vision studies and the early detection and treatment of retinal diseases.

© 2006 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4470) Medical optics and biotechnology : Ophthalmology

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: February 15, 2006
Revised Manuscript: April 6, 2006
Manuscript Accepted: April 9, 2006
Published: April 17, 2006

Virtual Issues
Vol. 1, Iss. 5 Virtual Journal for Biomedical Optics

Daniel X. Hammer, R. Daniel Ferguson, Chad E. Bigelow, Nicusor V. Iftimia, Teoman E. Ustun, and Stephen A. Burns, "Adaptive optics scanning laser ophthalmoscope for stabilized retinal imaging," Opt. Express 14, 3354-3367 (2006)

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  1. D. X. Hammer, R. D. Ferguson, J. C. Magill, M. A. White, A. E. Elsner, and R. H. Webb, "Image stabilization for scanning laser ophthalmoscopy," Opt. Express 10, 1542-1549 (2002). [PubMed]
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