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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 15, Iss. 10 — May. 14, 2007
  • pp: 6200–6209

Angle-resolved Optical Coherence Tomography with sequential angular selectivity for speckle reduction

A. E. Desjardins, B. J. Vakoc, W. Y. Oh, S. M. R. Motaghiannezam, G. J. Tearney, and B. E. Bouma  »View Author Affiliations


Optics Express, Vol. 15, Issue 10, pp. 6200-6209 (2007)
http://dx.doi.org/10.1364/OE.15.006200


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Abstract

We present a novel method for rapidly acquiring optical coherence tomography (OCT) images at multiple backscattering angles. By angularly compounding these images, high levels of speckle reduction were achieved. Signal-to-noise ratio (SNR) improvements of 3.4 dB were obtained from a homogeneous tissue phantom, which was in good agreement with the predictions of a statistical model of speckle that incorporated the optical parameters of the imaging system. In addition, the fast acquisition rate of the system (10 kHz A-line repetition rate) allowed angular compounding to be performed in vivo without significant motion artifacts. Speckle-reduced OCT images of human dermis show greatly improved delineation of tissue microstructure.

© 2007 Optical Society of America

OCIS Codes
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: February 13, 2007
Revised Manuscript: April 2, 2007
Manuscript Accepted: April 5, 2007
Published: May 4, 2007

Virtual Issues
Vol. 2, Iss. 6 Virtual Journal for Biomedical Optics

Citation
A. E. Desjardins, B. J. Vakoc, W. Y. Oh, S. M. Motaghiannezam, G. J. Tearney, and B. E. Bouma, "Angle-resolved Optical Coherence Tomography with sequential angular selectivity for speckle reduction," Opt. Express 15, 6200-6209 (2007)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-10-6200


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References

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