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Optics Express

Optics Express

  • Editor: C. Martijn de Sterke
  • Vol. 15, Iss. 10 — May. 14, 2007
  • pp: 6210–6217

Swept source optical coherence microscopy using a Fourier domain mode-locked laser

Shu-Wei Huang, Aaron D. Aguirre, Robert A. Huber, Desmond C. Adler, and James G. Fujimoto  »View Author Affiliations


Optics Express, Vol. 15, Issue 10, pp. 6210-6217 (2007)
http://dx.doi.org/10.1364/OE.15.006210


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Abstract

Swept source optical coherence microscopy (OCM) enables cellular resolution en face imaging as well as integration with optical coherence tomography (OCT) cross sectional imaging. A buffered Fourier domain mode-locked (FDML) laser light source provides high speed, three dimensional imaging. Image resolutions of 1.6 μm × 8 μm (transverse × axial) with a 220 μm × 220 μm field of view and sensitivity higher than 98 dB are achieved. Three dimensional cellular imaging is demonstrated in vivo in the Xenopus laevis tadpole and ex vivo in the rat kidney and human colon.

© 2007 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(140.3600) Lasers and laser optics : Lasers, tunable
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(180.1790) Microscopy : Confocal microscopy
(180.6900) Microscopy : Three-dimensional microscopy

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: March 12, 2007
Revised Manuscript: April 30, 2007
Manuscript Accepted: May 2, 2007
Published: May 4, 2007

Virtual Issues
Vol. 2, Iss. 6 Virtual Journal for Biomedical Optics

Citation
Shu-Wei Huang, Aaron D. Aguirre, Robert A. Huber, Desmond C. Adler, and James G. Fujimoto, "Swept source optical coherence microscopy using a Fourier domain mode-locked laser," Opt. Express 15, 6210-6217 (2007)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-10-6210


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