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Simultaneous dual-band ultra-high resolution optical coherence tomography
Felix Spöler, Stefan Kray, Patrik Grychtol, Barbara Hermes, Jörg Bornemann, Michael Först, and Heinrich Kurz »View Author Affiliations
1Institute for Semiconductor Electronics, RWTH Aachen University, Sommerfeldstr. 24, 52074 Aachen, Germany
2Institute of Pathology, University Hospital Aachen, Pauwelsstr. 30, 52074 Aachen, Germany
3Urological Clinic, University Hospital Aachen, Pauwelsstr. 30, 52074 Aachen, Germany
Optics Express, Vol. 15, Issue 17, pp. 10832-10841 (2007)
http://dx.doi.org/10.1364/OE.15.010832
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Abstract
Ultra-high resolution optical coherence tomography (OCT) imaging is demonstrated simultaneously at 840 nm and 1230 nm central wavelength using an off-the-shelf turn-key supercontinuum light source. Spectral filtering of the light source emission results in a double peak spectrum with average powers exceeding 100 mW and bandwidths exceeding 200 nm for each wavelength band. A free-space OCT setup optimized to support both wavelengths in parallel is introduced. OCT imaging of biological tissue ex vivo and in vivo is demonstrated with axial resolutions measured to be <2 µm and <4 µm at 840 nm and 1230 nm, respectively. This measuring scheme is used to extract spectroscopic features with outstanding spatial resolution enabling enhanced image contrast.
© 2007 Optical Society of America
OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics
ToC Category:
Medical Optics and Biotechnology
History
Original Manuscript: July 9, 2007
Revised Manuscript: August 8, 2007
Manuscript Accepted: August 9, 2007
Published: August 13, 2007
Virtual Issues
Vol. 2, Iss. 9 Virtual Journal for Biomedical Optics
Citation
Felix Spöler, Stefan Kray, Patrik Grychtol, Barbara Hermes, Jörg Bornemann, Michael Först, and Heinrich Kurz, "Simultaneous dual-band ultra-high resolution optical coherence tomography," Opt. Express 15, 10832-10841 (2007)
http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-17-10832
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References
- D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991). [CrossRef] [PubMed]
- E. A. Swanson, J. A. Izatt, M. R. Hee, D. Huang, C. P. Lin, J. S. Schumann, C. A. Puliafito, and J. G. Fujimoto, "In vivo retinal imaging by optical coherence tomography," Opt. Lett. 18, 1864-1866 (1993). [CrossRef] [PubMed]
- J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, "Micrometer-scale resolution imaging of the anterior eye in vivo with optical coherence tomography," Arch. Ophthalmol. 112, 1584-1589 (1994). [CrossRef] [PubMed]
- J. G. Fujimoto, "Optical coherence tomography for ultrahigh resolution in vivo imaging," Nat. Biotechnol. 21, 1361-1367 (2003). [CrossRef] [PubMed]
- D. Stifter, P. Burgholzer, O. Hoglinger, E. Götzinger, and C. K. Hitzenberger, "Polarisation-sensitive optical coherence tomography for material characterisation and strain-field mapping," Appl. Phys. A 76, 947-951 (2003). [CrossRef]
- B. Bouma, G. J. Tearney, S. A. Boppart, M. R. Hee, M. E. Brezinski, and J. G. Fujimoto, "High-resolutiom optical coherence tomography imaging using a mode-locked TiAl2O3 laser source," Opt. Lett. 20, 1486-1488 (1995). [CrossRef] [PubMed]
- B. E. Bouma, G. J. Tearney, I. P. Bilinsky, B. Golubovic, and J. G. Fujimoto, "Self-phase-modulated Kerr-lens mode-locked Cr:forsterite laser source for optical coherence tomography," Opt. Lett. 21, 1839-1841 (1996). [CrossRef] [PubMed]
- B. Povazay, K. Bizheva, A. Unterhuber, B. Hermann, H. Sattmann, A. F. Fercher, W. Drexler, A. Apolonski, W. J. Wadsworth, J. C. Knight, P. S. J. Russell, M. Vetterlein, and E. Scherzer, "Submicrometer axial resolution optical coherence tomography," Opt. Lett. 27, 1800-1802 (2002). [CrossRef]
- A. Unterhuber, B. Povazay, K. Bizheva, B. Hermann, H. Sattmann, A. Stingl, T. Le, M. Seefeld, R. Menzel, M. Preusser, H. Budka, C. Schubert, H. Reitsamer, P. K. Ahnelt, J. E. Morgan, A. Cowey, and W. Drexler, "Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomogram phy," Phys. Med. Biol. 49, 1235-1246 (2004). [CrossRef] [PubMed]
- K. Bizheva, B. Povazay, B. Hermann, H. Sattmann, W. Drexler, M. Mei, R. Holzwarth, T. Hoelzenbein, V. Wacheck, and H. Pehamberger, "Compact, broad-bandwidth fiber laser for sub-2-microm axial resolution optical coherence tomography in the 1300-nm wavelength region," Opt. Lett. 28, 707-709 (2003). [CrossRef] [PubMed]
- W. Drexler, "Ultrahigh-resolution optical coherence tomography," J. Biomed. Opt. 9, 47-74 (2004). [CrossRef] [PubMed]
- J. A. Izatt, M. D. Kulkami, S. Yazdanfar, J. K. Barton, and A. J. Welch, "In vivo bidirectional color Doppler flow imaging of picoliter blood volumes using optical coherence tomograghy," Opt. Lett. 22, 1439-1441 (1997). [CrossRef]
- J. F. deBoer, T. E. Milner, M. J. C. vanGemert, and J. S. Nelson, "Two-dimensional birefringence imaging in biological tissue by polarization-sensitive optical coherence tomography," Opt. Lett. 22, 934-936 (1997). [CrossRef]
- C. Vinegoni, J. S. Bredfeldt, D. L. Marks, and S. A. Boppart, "Nonlinear optical contrast enhancement for optical coherence tomography," Opt. Express 12, 331-341 (2004). [CrossRef] [PubMed]
- U. Morgner, W. Drexler, F. X. Kartner, X. D. Li, C. Pitris, E. P. Ippen, and J. G. Fujimoto, "Spectroscopic optical coherence tomography," Opt. Lett. 25, 111-113 (2000). [CrossRef]
- D. C. Adler, T. H. Ko, P. R. Herz, and J. G. Fujimoto, "Optical coherence tomography contrast enhancement using spectroscopic analysis with spectral autocorrelation," Opt. Express 12, 5487-5501 (2004). [CrossRef] [PubMed]
- D. J. Faber, E. G. Mik, M. C. G. Aalders, and T. G. van Leeuwen, "Toward assessment of blood oxygen saturation by spectroscopic optical coherence tomography," Opt. Lett. 30, 1015-1017 (2005). [CrossRef] [PubMed]
- J. M. Schmitt, A. Knüttel, M. Yadlowsky, and M. A. Eckhaus, "Optical-coherence tomography of a dense tissue: statistics of attenuation and backscattering," Phys. Med. Biol. 39, 1705-1720 (1994). [CrossRef] [PubMed]
- C. H. Yang, L. E. L. McGuckin, J. D. Simon, M. A. Choma, B. E. Applegate, and J. A. Izatt, "Spectral triangulation molecular contrast optical coherence tomography with indocyanine green as the contrast agent," Opt. Lett. 29, 2016-2018 (2004). [CrossRef] [PubMed]
- F. I. Feldchtein, G. V. Gelikonov, V. M. Gelikonov, R. R. Iksanov, R. V. Kuranov, A. M. Sergeev, N. D. Gladkova, M. N. Ourutina, J. A. Warren, and D. H. Reitze, "In vivo OCT imaging of hard and soft tissue of the oral cavity," Opt. Express 3, 239-250 (1998). [CrossRef] [PubMed]
- V. M. Gelikonov, G. V. Gelikonov, and F. I. Feldchtein, "Two-wavelength optical coherence tomography," Radiophys. Quantum Electron. 47, 848-859 (2004). [CrossRef]
- Y. Pan and D. L. Farkas, "Noninvasive imaging of living human skin with dual-wavelength optical coherence tomography in two and three dimensions," J. Biomed. Opt. 3, 446-455 (1998). [CrossRef]
- M. Pircher, E. Götzinger, R. Leitgeb, A. F. Fercher, and C. K. Hitzenberger, "Measurement and imaging of water concentration in human cornea with differential absorption optical coherence tomography," Opt. Express 11, 2190-2197 (2003). [CrossRef] [PubMed]
- J. M. Schmitt, S. H. Xiang, and K. M. Yung, "Differential absorption imaging with optical coherence tomography," J. Opt. Soc. Am. A 15, 2288-2296 (1998). [CrossRef]
- M. Pircher, E. Götzinger, R. Leitgeb, A. F. Fercher, and C. K. Hitzenberger, "Speckle reduction in optical coherence tomography by frequency compounding," J. Biomed. Opt. 8, 565-569 (2003). [CrossRef] [PubMed]
- S. J. Matcher, M. Cope, and D. T. Delpy, "In vivo measurements of the wavelength dependence of tissuescattering coefficients between 760 and 900 nm measured with time-resolved spectroscopy," Appl. Opt. 36, 386-396 (1997). [CrossRef] [PubMed]
- C. Yang, "Molecular contrast optical coherence tomography: a review," Photochem. Photobiol. 81, 215-237 (2005). [CrossRef]
- C. Y. Xu, P. S. Carney, and S. A. Boppart, "Wavelength-dependent scattering in spectroscopic optical coherence tomography," Opt. Express 13, 5450-5462 (2005). [CrossRef] [PubMed]
- A. D. Aguirre, N. Nishizawa, J. G. Fujimoto, W. Seitz, M. Lederer, and D. Kopf, "Continuum generation in a novel photonic crystal fiber for ultrahigh resolution optical coherence tomography at 800 nm and 1300 nm," Opt. Express 14, 1145-1160 (2006). [CrossRef] [PubMed]
- H. Wang and A. M. Rollins, "Optimization of dual-band continuum light source for ultrahigh-resolution optical coherence tomography," Appl. Opt. 46, 1787-1794 (2007). [CrossRef] [PubMed]
- T. Støren, A. Røyset, L. O. Svaasand, and T. Lindmo, "Measurement of dye diffusion in scattering tissue phantoms using dual-wavelength low-coherence interferometry," J. Biomed. Opt. 11, 014017 (2006). [CrossRef] [PubMed]
- A. Unterhuber, B. Povazay, K. Bizheva, B. Hermann, H. Sattmann, A. Stingl, T. Le, M. Seefeld, R. Menzel, M. Preusser, H. Budka, C. Schubert, H. Reitsamer, P. K. Ahnelt, J. E. Morgan, A. Cowey, and W. Drexler, "Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomogram phy," Phys. Med. Biol. 49, 1235-1246 (2004). [CrossRef] [PubMed]
- A. Unterhuber, B. Povazay, K. Bizheva, B. Hermann, H. Sattmann, A. Stingl, T. Le, M. Seefeld, R. Menzel, M. Preusser, H. Budka, C. Schubert, H. Reitsamer, P. K. Ahnelt, J. E. Morgan, A. Cowey, and W. Drexler, "Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomogram phy," Phys. Med. Biol. 49, 1235-1246 (2004). [CrossRef] [PubMed]
- K. Bizheva, B. Povazay, B. Hermann, H. Sattmann, W. Drexler, M. Mei, R. Holzwarth, T. Hoelzenbein, V. Wacheck, and H. Pehamberger, "Compact, broad-bandwidth fiber laser for sub-2-microm axial resolution optical coherence tomography in the 1300-nm wavelength region," Opt. Lett. 28, 707-709 (2003). [CrossRef] [PubMed]
- B. Povazay, K. Bizheva, A. Unterhuber, B. Hermann, H. Sattmann, A. F. Fercher, W. Drexler, A. Apolonski, W. J. Wadsworth, J. C. Knight, P. S. J. Russell, M. Vetterlein, and E. Scherzer, "Submicrometer axial resolution optical coherence tomography," Opt. Lett. 27, 1800-1802 (2002). [CrossRef]
- C. Y. Xu, P. S. Carney, and S. A. Boppart, "Wavelength-dependent scattering in spectroscopic optical coherence tomography," Opt. Express 13, 5450-5462 (2005). [CrossRef] [PubMed]
- C. Vinegoni, J. S. Bredfeldt, D. L. Marks, and S. A. Boppart, "Nonlinear optical contrast enhancement for optical coherence tomography," Opt. Express 12, 331-341 (2004). [CrossRef] [PubMed]
- B. Bouma, G. J. Tearney, S. A. Boppart, M. R. Hee, M. E. Brezinski, and J. G. Fujimoto, "High-resolutiom optical coherence tomography imaging using a mode-locked TiAl2O3 laser source," Opt. Lett. 20, 1486-1488 (1995). [CrossRef] [PubMed]
- A. Unterhuber, B. Povazay, K. Bizheva, B. Hermann, H. Sattmann, A. Stingl, T. Le, M. Seefeld, R. Menzel, M. Preusser, H. Budka, C. Schubert, H. Reitsamer, P. K. Ahnelt, J. E. Morgan, A. Cowey, and W. Drexler, "Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomogram phy," Phys. Med. Biol. 49, 1235-1246 (2004). [CrossRef] [PubMed]
- D. Stifter, P. Burgholzer, O. Hoglinger, E. Götzinger, and C. K. Hitzenberger, "Polarisation-sensitive optical coherence tomography for material characterisation and strain-field mapping," Appl. Phys. A 76, 947-951 (2003). [CrossRef]
- D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991). [CrossRef] [PubMed]
- A. Unterhuber, B. Povazay, K. Bizheva, B. Hermann, H. Sattmann, A. Stingl, T. Le, M. Seefeld, R. Menzel, M. Preusser, H. Budka, C. Schubert, H. Reitsamer, P. K. Ahnelt, J. E. Morgan, A. Cowey, and W. Drexler, "Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomogram phy," Phys. Med. Biol. 49, 1235-1246 (2004). [CrossRef] [PubMed]
- W. Drexler, "Ultrahigh-resolution optical coherence tomography," J. Biomed. Opt. 9, 47-74 (2004). [CrossRef] [PubMed]
- A. Unterhuber, B. Povazay, K. Bizheva, B. Hermann, H. Sattmann, A. Stingl, T. Le, M. Seefeld, R. Menzel, M. Preusser, H. Budka, C. Schubert, H. Reitsamer, P. K. Ahnelt, J. E. Morgan, A. Cowey, and W. Drexler, "Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomogram phy," Phys. Med. Biol. 49, 1235-1246 (2004). [CrossRef] [PubMed]
- K. Bizheva, B. Povazay, B. Hermann, H. Sattmann, W. Drexler, M. Mei, R. Holzwarth, T. Hoelzenbein, V. Wacheck, and H. Pehamberger, "Compact, broad-bandwidth fiber laser for sub-2-microm axial resolution optical coherence tomography in the 1300-nm wavelength region," Opt. Lett. 28, 707-709 (2003). [CrossRef] [PubMed]
- B. Povazay, K. Bizheva, A. Unterhuber, B. Hermann, H. Sattmann, A. F. Fercher, W. Drexler, A. Apolonski, W. J. Wadsworth, J. C. Knight, P. S. J. Russell, M. Vetterlein, and E. Scherzer, "Submicrometer axial resolution optical coherence tomography," Opt. Lett. 27, 1800-1802 (2002). [CrossRef]
- U. Morgner, W. Drexler, F. X. Kartner, X. D. Li, C. Pitris, E. P. Ippen, and J. G. Fujimoto, "Spectroscopic optical coherence tomography," Opt. Lett. 25, 111-113 (2000). [CrossRef]
- J. M. Schmitt, A. Knüttel, M. Yadlowsky, and M. A. Eckhaus, "Optical-coherence tomography of a dense tissue: statistics of attenuation and backscattering," Phys. Med. Biol. 39, 1705-1720 (1994). [CrossRef] [PubMed]
- Y. Pan and D. L. Farkas, "Noninvasive imaging of living human skin with dual-wavelength optical coherence tomography in two and three dimensions," J. Biomed. Opt. 3, 446-455 (1998). [CrossRef]
- V. M. Gelikonov, G. V. Gelikonov, and F. I. Feldchtein, "Two-wavelength optical coherence tomography," Radiophys. Quantum Electron. 47, 848-859 (2004). [CrossRef]
- F. I. Feldchtein, G. V. Gelikonov, V. M. Gelikonov, R. R. Iksanov, R. V. Kuranov, A. M. Sergeev, N. D. Gladkova, M. N. Ourutina, J. A. Warren, and D. H. Reitze, "In vivo OCT imaging of hard and soft tissue of the oral cavity," Opt. Express 3, 239-250 (1998). [CrossRef] [PubMed]
- M. Pircher, E. Götzinger, R. Leitgeb, A. F. Fercher, and C. K. Hitzenberger, "Measurement and imaging of water concentration in human cornea with differential absorption optical coherence tomography," Opt. Express 11, 2190-2197 (2003). [CrossRef] [PubMed]
- M. Pircher, E. Götzinger, R. Leitgeb, A. F. Fercher, and C. K. Hitzenberger, "Speckle reduction in optical coherence tomography by frequency compounding," J. Biomed. Opt. 8, 565-569 (2003). [CrossRef] [PubMed]
- B. Povazay, K. Bizheva, A. Unterhuber, B. Hermann, H. Sattmann, A. F. Fercher, W. Drexler, A. Apolonski, W. J. Wadsworth, J. C. Knight, P. S. J. Russell, M. Vetterlein, and E. Scherzer, "Submicrometer axial resolution optical coherence tomography," Opt. Lett. 27, 1800-1802 (2002). [CrossRef]
- D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991). [CrossRef] [PubMed]
- A. D. Aguirre, N. Nishizawa, J. G. Fujimoto, W. Seitz, M. Lederer, and D. Kopf, "Continuum generation in a novel photonic crystal fiber for ultrahigh resolution optical coherence tomography at 800 nm and 1300 nm," Opt. Express 14, 1145-1160 (2006). [CrossRef] [PubMed]
- D. C. Adler, T. H. Ko, P. R. Herz, and J. G. Fujimoto, "Optical coherence tomography contrast enhancement using spectroscopic analysis with spectral autocorrelation," Opt. Express 12, 5487-5501 (2004). [CrossRef] [PubMed]
- J. G. Fujimoto, "Optical coherence tomography for ultrahigh resolution in vivo imaging," Nat. Biotechnol. 21, 1361-1367 (2003). [CrossRef] [PubMed]
- U. Morgner, W. Drexler, F. X. Kartner, X. D. Li, C. Pitris, E. P. Ippen, and J. G. Fujimoto, "Spectroscopic optical coherence tomography," Opt. Lett. 25, 111-113 (2000). [CrossRef]
- B. E. Bouma, G. J. Tearney, I. P. Bilinsky, B. Golubovic, and J. G. Fujimoto, "Self-phase-modulated Kerr-lens mode-locked Cr:forsterite laser source for optical coherence tomography," Opt. Lett. 21, 1839-1841 (1996). [CrossRef] [PubMed]
- B. Bouma, G. J. Tearney, S. A. Boppart, M. R. Hee, M. E. Brezinski, and J. G. Fujimoto, "High-resolutiom optical coherence tomography imaging using a mode-locked TiAl2O3 laser source," Opt. Lett. 20, 1486-1488 (1995). [CrossRef] [PubMed]
- J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, "Micrometer-scale resolution imaging of the anterior eye in vivo with optical coherence tomography," Arch. Ophthalmol. 112, 1584-1589 (1994). [CrossRef] [PubMed]
- E. A. Swanson, J. A. Izatt, M. R. Hee, D. Huang, C. P. Lin, J. S. Schumann, C. A. Puliafito, and J. G. Fujimoto, "In vivo retinal imaging by optical coherence tomography," Opt. Lett. 18, 1864-1866 (1993). [CrossRef] [PubMed]
- D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991). [CrossRef] [PubMed]
- V. M. Gelikonov, G. V. Gelikonov, and F. I. Feldchtein, "Two-wavelength optical coherence tomography," Radiophys. Quantum Electron. 47, 848-859 (2004). [CrossRef]
- F. I. Feldchtein, G. V. Gelikonov, V. M. Gelikonov, R. R. Iksanov, R. V. Kuranov, A. M. Sergeev, N. D. Gladkova, M. N. Ourutina, J. A. Warren, and D. H. Reitze, "In vivo OCT imaging of hard and soft tissue of the oral cavity," Opt. Express 3, 239-250 (1998). [CrossRef] [PubMed]
- V. M. Gelikonov, G. V. Gelikonov, and F. I. Feldchtein, "Two-wavelength optical coherence tomography," Radiophys. Quantum Electron. 47, 848-859 (2004). [CrossRef]
- F. I. Feldchtein, G. V. Gelikonov, V. M. Gelikonov, R. R. Iksanov, R. V. Kuranov, A. M. Sergeev, N. D. Gladkova, M. N. Ourutina, J. A. Warren, and D. H. Reitze, "In vivo OCT imaging of hard and soft tissue of the oral cavity," Opt. Express 3, 239-250 (1998). [CrossRef] [PubMed]
- D. Stifter, P. Burgholzer, O. Hoglinger, E. Götzinger, and C. K. Hitzenberger, "Polarisation-sensitive optical coherence tomography for material characterisation and strain-field mapping," Appl. Phys. A 76, 947-951 (2003). [CrossRef]
- M. Pircher, E. Götzinger, R. Leitgeb, A. F. Fercher, and C. K. Hitzenberger, "Measurement and imaging of water concentration in human cornea with differential absorption optical coherence tomography," Opt. Express 11, 2190-2197 (2003). [CrossRef] [PubMed]
- M. Pircher, E. Götzinger, R. Leitgeb, A. F. Fercher, and C. K. Hitzenberger, "Speckle reduction in optical coherence tomography by frequency compounding," J. Biomed. Opt. 8, 565-569 (2003). [CrossRef] [PubMed]
- D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991). [CrossRef] [PubMed]
- B. Bouma, G. J. Tearney, S. A. Boppart, M. R. Hee, M. E. Brezinski, and J. G. Fujimoto, "High-resolutiom optical coherence tomography imaging using a mode-locked TiAl2O3 laser source," Opt. Lett. 20, 1486-1488 (1995). [CrossRef] [PubMed]
- J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, "Micrometer-scale resolution imaging of the anterior eye in vivo with optical coherence tomography," Arch. Ophthalmol. 112, 1584-1589 (1994). [CrossRef] [PubMed]
- E. A. Swanson, J. A. Izatt, M. R. Hee, D. Huang, C. P. Lin, J. S. Schumann, C. A. Puliafito, and J. G. Fujimoto, "In vivo retinal imaging by optical coherence tomography," Opt. Lett. 18, 1864-1866 (1993). [CrossRef] [PubMed]
- D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991). [CrossRef] [PubMed]
- A. Unterhuber, B. Povazay, K. Bizheva, B. Hermann, H. Sattmann, A. Stingl, T. Le, M. Seefeld, R. Menzel, M. Preusser, H. Budka, C. Schubert, H. Reitsamer, P. K. Ahnelt, J. E. Morgan, A. Cowey, and W. Drexler, "Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomogram phy," Phys. Med. Biol. 49, 1235-1246 (2004). [CrossRef] [PubMed]
- K. Bizheva, B. Povazay, B. Hermann, H. Sattmann, W. Drexler, M. Mei, R. Holzwarth, T. Hoelzenbein, V. Wacheck, and H. Pehamberger, "Compact, broad-bandwidth fiber laser for sub-2-microm axial resolution optical coherence tomography in the 1300-nm wavelength region," Opt. Lett. 28, 707-709 (2003). [CrossRef] [PubMed]
- B. Povazay, K. Bizheva, A. Unterhuber, B. Hermann, H. Sattmann, A. F. Fercher, W. Drexler, A. Apolonski, W. J. Wadsworth, J. C. Knight, P. S. J. Russell, M. Vetterlein, and E. Scherzer, "Submicrometer axial resolution optical coherence tomography," Opt. Lett. 27, 1800-1802 (2002). [CrossRef]
- D. Stifter, P. Burgholzer, O. Hoglinger, E. Götzinger, and C. K. Hitzenberger, "Polarisation-sensitive optical coherence tomography for material characterisation and strain-field mapping," Appl. Phys. A 76, 947-951 (2003). [CrossRef]
- M. Pircher, E. Götzinger, R. Leitgeb, A. F. Fercher, and C. K. Hitzenberger, "Speckle reduction in optical coherence tomography by frequency compounding," J. Biomed. Opt. 8, 565-569 (2003). [CrossRef] [PubMed]
- M. Pircher, E. Götzinger, R. Leitgeb, A. F. Fercher, and C. K. Hitzenberger, "Measurement and imaging of water concentration in human cornea with differential absorption optical coherence tomography," Opt. Express 11, 2190-2197 (2003). [CrossRef] [PubMed]
- K. Bizheva, B. Povazay, B. Hermann, H. Sattmann, W. Drexler, M. Mei, R. Holzwarth, T. Hoelzenbein, V. Wacheck, and H. Pehamberger, "Compact, broad-bandwidth fiber laser for sub-2-microm axial resolution optical coherence tomography in the 1300-nm wavelength region," Opt. Lett. 28, 707-709 (2003). [CrossRef] [PubMed]
- D. Stifter, P. Burgholzer, O. Hoglinger, E. Götzinger, and C. K. Hitzenberger, "Polarisation-sensitive optical coherence tomography for material characterisation and strain-field mapping," Appl. Phys. A 76, 947-951 (2003). [CrossRef]
- K. Bizheva, B. Povazay, B. Hermann, H. Sattmann, W. Drexler, M. Mei, R. Holzwarth, T. Hoelzenbein, V. Wacheck, and H. Pehamberger, "Compact, broad-bandwidth fiber laser for sub-2-microm axial resolution optical coherence tomography in the 1300-nm wavelength region," Opt. Lett. 28, 707-709 (2003). [CrossRef] [PubMed]
- J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, "Micrometer-scale resolution imaging of the anterior eye in vivo with optical coherence tomography," Arch. Ophthalmol. 112, 1584-1589 (1994). [CrossRef] [PubMed]
- E. A. Swanson, J. A. Izatt, M. R. Hee, D. Huang, C. P. Lin, J. S. Schumann, C. A. Puliafito, and J. G. Fujimoto, "In vivo retinal imaging by optical coherence tomography," Opt. Lett. 18, 1864-1866 (1993). [CrossRef] [PubMed]
- D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991). [CrossRef] [PubMed]
- C. H. Yang, L. E. L. McGuckin, J. D. Simon, M. A. Choma, B. E. Applegate, and J. A. Izatt, "Spectral triangulation molecular contrast optical coherence tomography with indocyanine green as the contrast agent," Opt. Lett. 29, 2016-2018 (2004). [CrossRef] [PubMed]
- J. A. Izatt, M. D. Kulkami, S. Yazdanfar, J. K. Barton, and A. J. Welch, "In vivo bidirectional color Doppler flow imaging of picoliter blood volumes using optical coherence tomograghy," Opt. Lett. 22, 1439-1441 (1997). [CrossRef]
- J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, "Micrometer-scale resolution imaging of the anterior eye in vivo with optical coherence tomography," Arch. Ophthalmol. 112, 1584-1589 (1994). [CrossRef] [PubMed]
- E. A. Swanson, J. A. Izatt, M. R. Hee, D. Huang, C. P. Lin, J. S. Schumann, C. A. Puliafito, and J. G. Fujimoto, "In vivo retinal imaging by optical coherence tomography," Opt. Lett. 18, 1864-1866 (1993). [CrossRef] [PubMed]
- J. M. Schmitt, A. Knüttel, M. Yadlowsky, and M. A. Eckhaus, "Optical-coherence tomography of a dense tissue: statistics of attenuation and backscattering," Phys. Med. Biol. 39, 1705-1720 (1994). [CrossRef] [PubMed]
- A. Unterhuber, B. Povazay, K. Bizheva, B. Hermann, H. Sattmann, A. Stingl, T. Le, M. Seefeld, R. Menzel, M. Preusser, H. Budka, C. Schubert, H. Reitsamer, P. K. Ahnelt, J. E. Morgan, A. Cowey, and W. Drexler, "Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomogram phy," Phys. Med. Biol. 49, 1235-1246 (2004). [CrossRef] [PubMed]
- M. Pircher, E. Götzinger, R. Leitgeb, A. F. Fercher, and C. K. Hitzenberger, "Speckle reduction in optical coherence tomography by frequency compounding," J. Biomed. Opt. 8, 565-569 (2003). [CrossRef] [PubMed]
- M. Pircher, E. Götzinger, R. Leitgeb, A. F. Fercher, and C. K. Hitzenberger, "Measurement and imaging of water concentration in human cornea with differential absorption optical coherence tomography," Opt. Express 11, 2190-2197 (2003). [CrossRef] [PubMed]
- J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, "Micrometer-scale resolution imaging of the anterior eye in vivo with optical coherence tomography," Arch. Ophthalmol. 112, 1584-1589 (1994). [CrossRef] [PubMed]
- E. A. Swanson, J. A. Izatt, M. R. Hee, D. Huang, C. P. Lin, J. S. Schumann, C. A. Puliafito, and J. G. Fujimoto, "In vivo retinal imaging by optical coherence tomography," Opt. Lett. 18, 1864-1866 (1993). [CrossRef] [PubMed]
- D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991). [CrossRef] [PubMed]
- T. Støren, A. Røyset, L. O. Svaasand, and T. Lindmo, "Measurement of dye diffusion in scattering tissue phantoms using dual-wavelength low-coherence interferometry," J. Biomed. Opt. 11, 014017 (2006). [CrossRef] [PubMed]
- K. Bizheva, B. Povazay, B. Hermann, H. Sattmann, W. Drexler, M. Mei, R. Holzwarth, T. Hoelzenbein, V. Wacheck, and H. Pehamberger, "Compact, broad-bandwidth fiber laser for sub-2-microm axial resolution optical coherence tomography in the 1300-nm wavelength region," Opt. Lett. 28, 707-709 (2003). [CrossRef] [PubMed]
- A. Unterhuber, B. Povazay, K. Bizheva, B. Hermann, H. Sattmann, A. Stingl, T. Le, M. Seefeld, R. Menzel, M. Preusser, H. Budka, C. Schubert, H. Reitsamer, P. K. Ahnelt, J. E. Morgan, A. Cowey, and W. Drexler, "Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomogram phy," Phys. Med. Biol. 49, 1235-1246 (2004). [CrossRef] [PubMed]
- A. Unterhuber, B. Povazay, K. Bizheva, B. Hermann, H. Sattmann, A. Stingl, T. Le, M. Seefeld, R. Menzel, M. Preusser, H. Budka, C. Schubert, H. Reitsamer, P. K. Ahnelt, J. E. Morgan, A. Cowey, and W. Drexler, "Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomogram phy," Phys. Med. Biol. 49, 1235-1246 (2004). [CrossRef] [PubMed]
- Y. Pan and D. L. Farkas, "Noninvasive imaging of living human skin with dual-wavelength optical coherence tomography in two and three dimensions," J. Biomed. Opt. 3, 446-455 (1998). [CrossRef]
- K. Bizheva, B. Povazay, B. Hermann, H. Sattmann, W. Drexler, M. Mei, R. Holzwarth, T. Hoelzenbein, V. Wacheck, and H. Pehamberger, "Compact, broad-bandwidth fiber laser for sub-2-microm axial resolution optical coherence tomography in the 1300-nm wavelength region," Opt. Lett. 28, 707-709 (2003). [CrossRef] [PubMed]
- M. Pircher, E. Götzinger, R. Leitgeb, A. F. Fercher, and C. K. Hitzenberger, "Measurement and imaging of water concentration in human cornea with differential absorption optical coherence tomography," Opt. Express 11, 2190-2197 (2003). [CrossRef] [PubMed]
- M. Pircher, E. Götzinger, R. Leitgeb, A. F. Fercher, and C. K. Hitzenberger, "Speckle reduction in optical coherence tomography by frequency compounding," J. Biomed. Opt. 8, 565-569 (2003). [CrossRef] [PubMed]
- A. Unterhuber, B. Povazay, K. Bizheva, B. Hermann, H. Sattmann, A. Stingl, T. Le, M. Seefeld, R. Menzel, M. Preusser, H. Budka, C. Schubert, H. Reitsamer, P. K. Ahnelt, J. E. Morgan, A. Cowey, and W. Drexler, "Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomogram phy," Phys. Med. Biol. 49, 1235-1246 (2004). [CrossRef] [PubMed]
- K. Bizheva, B. Povazay, B. Hermann, H. Sattmann, W. Drexler, M. Mei, R. Holzwarth, T. Hoelzenbein, V. Wacheck, and H. Pehamberger, "Compact, broad-bandwidth fiber laser for sub-2-microm axial resolution optical coherence tomography in the 1300-nm wavelength region," Opt. Lett. 28, 707-709 (2003). [CrossRef] [PubMed]
- B. Povazay, K. Bizheva, A. Unterhuber, B. Hermann, H. Sattmann, A. F. Fercher, W. Drexler, A. Apolonski, W. J. Wadsworth, J. C. Knight, P. S. J. Russell, M. Vetterlein, and E. Scherzer, "Submicrometer axial resolution optical coherence tomography," Opt. Lett. 27, 1800-1802 (2002). [CrossRef]
- A. Unterhuber, B. Povazay, K. Bizheva, B. Hermann, H. Sattmann, A. Stingl, T. Le, M. Seefeld, R. Menzel, M. Preusser, H. Budka, C. Schubert, H. Reitsamer, P. K. Ahnelt, J. E. Morgan, A. Cowey, and W. Drexler, "Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomogram phy," Phys. Med. Biol. 49, 1235-1246 (2004). [CrossRef] [PubMed]
- J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, "Micrometer-scale resolution imaging of the anterior eye in vivo with optical coherence tomography," Arch. Ophthalmol. 112, 1584-1589 (1994). [CrossRef] [PubMed]
- E. A. Swanson, J. A. Izatt, M. R. Hee, D. Huang, C. P. Lin, J. S. Schumann, C. A. Puliafito, and J. G. Fujimoto, "In vivo retinal imaging by optical coherence tomography," Opt. Lett. 18, 1864-1866 (1993). [CrossRef] [PubMed]
- D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991). [CrossRef] [PubMed]
- A. Unterhuber, B. Povazay, K. Bizheva, B. Hermann, H. Sattmann, A. Stingl, T. Le, M. Seefeld, R. Menzel, M. Preusser, H. Budka, C. Schubert, H. Reitsamer, P. K. Ahnelt, J. E. Morgan, A. Cowey, and W. Drexler, "Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomogram phy," Phys. Med. Biol. 49, 1235-1246 (2004). [CrossRef] [PubMed]
- T. Støren, A. Røyset, L. O. Svaasand, and T. Lindmo, "Measurement of dye diffusion in scattering tissue phantoms using dual-wavelength low-coherence interferometry," J. Biomed. Opt. 11, 014017 (2006). [CrossRef] [PubMed]
- A. Unterhuber, B. Povazay, K. Bizheva, B. Hermann, H. Sattmann, A. Stingl, T. Le, M. Seefeld, R. Menzel, M. Preusser, H. Budka, C. Schubert, H. Reitsamer, P. K. Ahnelt, J. E. Morgan, A. Cowey, and W. Drexler, "Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomogram phy," Phys. Med. Biol. 49, 1235-1246 (2004). [CrossRef] [PubMed]
- K. Bizheva, B. Povazay, B. Hermann, H. Sattmann, W. Drexler, M. Mei, R. Holzwarth, T. Hoelzenbein, V. Wacheck, and H. Pehamberger, "Compact, broad-bandwidth fiber laser for sub-2-microm axial resolution optical coherence tomography in the 1300-nm wavelength region," Opt. Lett. 28, 707-709 (2003). [CrossRef] [PubMed]
- B. Povazay, K. Bizheva, A. Unterhuber, B. Hermann, H. Sattmann, A. F. Fercher, W. Drexler, A. Apolonski, W. J. Wadsworth, J. C. Knight, P. S. J. Russell, M. Vetterlein, and E. Scherzer, "Submicrometer axial resolution optical coherence tomography," Opt. Lett. 27, 1800-1802 (2002). [CrossRef]
- J. M. Schmitt, S. H. Xiang, and K. M. Yung, "Differential absorption imaging with optical coherence tomography," J. Opt. Soc. Am. A 15, 2288-2296 (1998). [CrossRef]
- J. M. Schmitt, A. Knüttel, M. Yadlowsky, and M. A. Eckhaus, "Optical-coherence tomography of a dense tissue: statistics of attenuation and backscattering," Phys. Med. Biol. 39, 1705-1720 (1994). [CrossRef] [PubMed]
- A. Unterhuber, B. Povazay, K. Bizheva, B. Hermann, H. Sattmann, A. Stingl, T. Le, M. Seefeld, R. Menzel, M. Preusser, H. Budka, C. Schubert, H. Reitsamer, P. K. Ahnelt, J. E. Morgan, A. Cowey, and W. Drexler, "Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomogram phy," Phys. Med. Biol. 49, 1235-1246 (2004). [CrossRef] [PubMed]
- J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, "Micrometer-scale resolution imaging of the anterior eye in vivo with optical coherence tomography," Arch. Ophthalmol. 112, 1584-1589 (1994). [CrossRef] [PubMed]
- D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991). [CrossRef] [PubMed]
- A. Unterhuber, B. Povazay, K. Bizheva, B. Hermann, H. Sattmann, A. Stingl, T. Le, M. Seefeld, R. Menzel, M. Preusser, H. Budka, C. Schubert, H. Reitsamer, P. K. Ahnelt, J. E. Morgan, A. Cowey, and W. Drexler, "Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomogram phy," Phys. Med. Biol. 49, 1235-1246 (2004). [CrossRef] [PubMed]
- D. Stifter, P. Burgholzer, O. Hoglinger, E. Götzinger, and C. K. Hitzenberger, "Polarisation-sensitive optical coherence tomography for material characterisation and strain-field mapping," Appl. Phys. A 76, 947-951 (2003). [CrossRef]
- A. Unterhuber, B. Povazay, K. Bizheva, B. Hermann, H. Sattmann, A. Stingl, T. Le, M. Seefeld, R. Menzel, M. Preusser, H. Budka, C. Schubert, H. Reitsamer, P. K. Ahnelt, J. E. Morgan, A. Cowey, and W. Drexler, "Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomogram phy," Phys. Med. Biol. 49, 1235-1246 (2004). [CrossRef] [PubMed]
- D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991). [CrossRef] [PubMed]
- T. Støren, A. Røyset, L. O. Svaasand, and T. Lindmo, "Measurement of dye diffusion in scattering tissue phantoms using dual-wavelength low-coherence interferometry," J. Biomed. Opt. 11, 014017 (2006). [CrossRef] [PubMed]
- T. Støren, A. Røyset, L. O. Svaasand, and T. Lindmo, "Measurement of dye diffusion in scattering tissue phantoms using dual-wavelength low-coherence interferometry," J. Biomed. Opt. 11, 014017 (2006). [CrossRef] [PubMed]
- J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, "Micrometer-scale resolution imaging of the anterior eye in vivo with optical coherence tomography," Arch. Ophthalmol. 112, 1584-1589 (1994). [CrossRef] [PubMed]
- E. A. Swanson, J. A. Izatt, M. R. Hee, D. Huang, C. P. Lin, J. S. Schumann, C. A. Puliafito, and J. G. Fujimoto, "In vivo retinal imaging by optical coherence tomography," Opt. Lett. 18, 1864-1866 (1993). [CrossRef] [PubMed]
- D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991). [CrossRef] [PubMed]
- B. E. Bouma, G. J. Tearney, I. P. Bilinsky, B. Golubovic, and J. G. Fujimoto, "Self-phase-modulated Kerr-lens mode-locked Cr:forsterite laser source for optical coherence tomography," Opt. Lett. 21, 1839-1841 (1996). [CrossRef] [PubMed]
- B. Bouma, G. J. Tearney, S. A. Boppart, M. R. Hee, M. E. Brezinski, and J. G. Fujimoto, "High-resolutiom optical coherence tomography imaging using a mode-locked TiAl2O3 laser source," Opt. Lett. 20, 1486-1488 (1995). [CrossRef] [PubMed]
- A. Unterhuber, B. Povazay, K. Bizheva, B. Hermann, H. Sattmann, A. Stingl, T. Le, M. Seefeld, R. Menzel, M. Preusser, H. Budka, C. Schubert, H. Reitsamer, P. K. Ahnelt, J. E. Morgan, A. Cowey, and W. Drexler, "Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomogram phy," Phys. Med. Biol. 49, 1235-1246 (2004). [CrossRef] [PubMed]
- B. Povazay, K. Bizheva, A. Unterhuber, B. Hermann, H. Sattmann, A. F. Fercher, W. Drexler, A. Apolonski, W. J. Wadsworth, J. C. Knight, P. S. J. Russell, M. Vetterlein, and E. Scherzer, "Submicrometer axial resolution optical coherence tomography," Opt. Lett. 27, 1800-1802 (2002). [CrossRef]
- K. Bizheva, B. Povazay, B. Hermann, H. Sattmann, W. Drexler, M. Mei, R. Holzwarth, T. Hoelzenbein, V. Wacheck, and H. Pehamberger, "Compact, broad-bandwidth fiber laser for sub-2-microm axial resolution optical coherence tomography in the 1300-nm wavelength region," Opt. Lett. 28, 707-709 (2003). [CrossRef] [PubMed]
- J. M. Schmitt, A. Knüttel, M. Yadlowsky, and M. A. Eckhaus, "Optical-coherence tomography of a dense tissue: statistics of attenuation and backscattering," Phys. Med. Biol. 39, 1705-1720 (1994). [CrossRef] [PubMed]
- C. Yang, "Molecular contrast optical coherence tomography: a review," Photochem. Photobiol. 81, 215-237 (2005). [CrossRef]
Appl. Opt.
- S. J. Matcher, M. Cope, and D. T. Delpy, "In vivo measurements of the wavelength dependence of tissuescattering coefficients between 760 and 900 nm measured with time-resolved spectroscopy," Appl. Opt. 36, 386-396 (1997). [CrossRef] [PubMed]
- H. Wang and A. M. Rollins, "Optimization of dual-band continuum light source for ultrahigh-resolution optical coherence tomography," Appl. Opt. 46, 1787-1794 (2007). [CrossRef] [PubMed]
Appl. Phys. A
- D. Stifter, P. Burgholzer, O. Hoglinger, E. Götzinger, and C. K. Hitzenberger, "Polarisation-sensitive optical coherence tomography for material characterisation and strain-field mapping," Appl. Phys. A 76, 947-951 (2003). [CrossRef]
Arch. Ophthalmol.
- J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, "Micrometer-scale resolution imaging of the anterior eye in vivo with optical coherence tomography," Arch. Ophthalmol. 112, 1584-1589 (1994). [CrossRef] [PubMed]
J. Biomed. Opt.
- W. Drexler, "Ultrahigh-resolution optical coherence tomography," J. Biomed. Opt. 9, 47-74 (2004). [CrossRef] [PubMed]
- T. Støren, A. Røyset, L. O. Svaasand, and T. Lindmo, "Measurement of dye diffusion in scattering tissue phantoms using dual-wavelength low-coherence interferometry," J. Biomed. Opt. 11, 014017 (2006). [CrossRef] [PubMed]
- M. Pircher, E. Götzinger, R. Leitgeb, A. F. Fercher, and C. K. Hitzenberger, "Speckle reduction in optical coherence tomography by frequency compounding," J. Biomed. Opt. 8, 565-569 (2003). [CrossRef] [PubMed]
- Y. Pan and D. L. Farkas, "Noninvasive imaging of living human skin with dual-wavelength optical coherence tomography in two and three dimensions," J. Biomed. Opt. 3, 446-455 (1998). [CrossRef]
J. Opt. Soc. Am. A
- J. M. Schmitt, S. H. Xiang, and K. M. Yung, "Differential absorption imaging with optical coherence tomography," J. Opt. Soc. Am. A 15, 2288-2296 (1998). [CrossRef]
Nat. Biotechnol.
- J. G. Fujimoto, "Optical coherence tomography for ultrahigh resolution in vivo imaging," Nat. Biotechnol. 21, 1361-1367 (2003). [CrossRef] [PubMed]
Opt. Express
- C. Vinegoni, J. S. Bredfeldt, D. L. Marks, and S. A. Boppart, "Nonlinear optical contrast enhancement for optical coherence tomography," Opt. Express 12, 331-341 (2004). [CrossRef] [PubMed]
- D. C. Adler, T. H. Ko, P. R. Herz, and J. G. Fujimoto, "Optical coherence tomography contrast enhancement using spectroscopic analysis with spectral autocorrelation," Opt. Express 12, 5487-5501 (2004). [CrossRef] [PubMed]
- M. Pircher, E. Götzinger, R. Leitgeb, A. F. Fercher, and C. K. Hitzenberger, "Measurement and imaging of water concentration in human cornea with differential absorption optical coherence tomography," Opt. Express 11, 2190-2197 (2003). [CrossRef] [PubMed]
- F. I. Feldchtein, G. V. Gelikonov, V. M. Gelikonov, R. R. Iksanov, R. V. Kuranov, A. M. Sergeev, N. D. Gladkova, M. N. Ourutina, J. A. Warren, and D. H. Reitze, "In vivo OCT imaging of hard and soft tissue of the oral cavity," Opt. Express 3, 239-250 (1998). [CrossRef] [PubMed]
- C. Y. Xu, P. S. Carney, and S. A. Boppart, "Wavelength-dependent scattering in spectroscopic optical coherence tomography," Opt. Express 13, 5450-5462 (2005). [CrossRef] [PubMed]
- A. D. Aguirre, N. Nishizawa, J. G. Fujimoto, W. Seitz, M. Lederer, and D. Kopf, "Continuum generation in a novel photonic crystal fiber for ultrahigh resolution optical coherence tomography at 800 nm and 1300 nm," Opt. Express 14, 1145-1160 (2006). [CrossRef] [PubMed]
Opt. Lett.
- D. J. Faber, E. G. Mik, M. C. G. Aalders, and T. G. van Leeuwen, "Toward assessment of blood oxygen saturation by spectroscopic optical coherence tomography," Opt. Lett. 30, 1015-1017 (2005). [CrossRef] [PubMed]
- K. Bizheva, B. Povazay, B. Hermann, H. Sattmann, W. Drexler, M. Mei, R. Holzwarth, T. Hoelzenbein, V. Wacheck, and H. Pehamberger, "Compact, broad-bandwidth fiber laser for sub-2-microm axial resolution optical coherence tomography in the 1300-nm wavelength region," Opt. Lett. 28, 707-709 (2003). [CrossRef] [PubMed]
- C. H. Yang, L. E. L. McGuckin, J. D. Simon, M. A. Choma, B. E. Applegate, and J. A. Izatt, "Spectral triangulation molecular contrast optical coherence tomography with indocyanine green as the contrast agent," Opt. Lett. 29, 2016-2018 (2004). [CrossRef] [PubMed]
- U. Morgner, W. Drexler, F. X. Kartner, X. D. Li, C. Pitris, E. P. Ippen, and J. G. Fujimoto, "Spectroscopic optical coherence tomography," Opt. Lett. 25, 111-113 (2000). [CrossRef]
- J. A. Izatt, M. D. Kulkami, S. Yazdanfar, J. K. Barton, and A. J. Welch, "In vivo bidirectional color Doppler flow imaging of picoliter blood volumes using optical coherence tomograghy," Opt. Lett. 22, 1439-1441 (1997). [CrossRef]
- J. F. deBoer, T. E. Milner, M. J. C. vanGemert, and J. S. Nelson, "Two-dimensional birefringence imaging in biological tissue by polarization-sensitive optical coherence tomography," Opt. Lett. 22, 934-936 (1997). [CrossRef]
- E. A. Swanson, J. A. Izatt, M. R. Hee, D. Huang, C. P. Lin, J. S. Schumann, C. A. Puliafito, and J. G. Fujimoto, "In vivo retinal imaging by optical coherence tomography," Opt. Lett. 18, 1864-1866 (1993). [CrossRef] [PubMed]
- B. Bouma, G. J. Tearney, S. A. Boppart, M. R. Hee, M. E. Brezinski, and J. G. Fujimoto, "High-resolutiom optical coherence tomography imaging using a mode-locked TiAl2O3 laser source," Opt. Lett. 20, 1486-1488 (1995). [CrossRef] [PubMed]
- B. E. Bouma, G. J. Tearney, I. P. Bilinsky, B. Golubovic, and J. G. Fujimoto, "Self-phase-modulated Kerr-lens mode-locked Cr:forsterite laser source for optical coherence tomography," Opt. Lett. 21, 1839-1841 (1996). [CrossRef] [PubMed]
- B. Povazay, K. Bizheva, A. Unterhuber, B. Hermann, H. Sattmann, A. F. Fercher, W. Drexler, A. Apolonski, W. J. Wadsworth, J. C. Knight, P. S. J. Russell, M. Vetterlein, and E. Scherzer, "Submicrometer axial resolution optical coherence tomography," Opt. Lett. 27, 1800-1802 (2002). [CrossRef]
Photochem. Photobiol.
- C. Yang, "Molecular contrast optical coherence tomography: a review," Photochem. Photobiol. 81, 215-237 (2005). [CrossRef]
Phys. Med. Biol.
- A. Unterhuber, B. Povazay, K. Bizheva, B. Hermann, H. Sattmann, A. Stingl, T. Le, M. Seefeld, R. Menzel, M. Preusser, H. Budka, C. Schubert, H. Reitsamer, P. K. Ahnelt, J. E. Morgan, A. Cowey, and W. Drexler, "Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomogram phy," Phys. Med. Biol. 49, 1235-1246 (2004). [CrossRef] [PubMed]
- J. M. Schmitt, A. Knüttel, M. Yadlowsky, and M. A. Eckhaus, "Optical-coherence tomography of a dense tissue: statistics of attenuation and backscattering," Phys. Med. Biol. 39, 1705-1720 (1994). [CrossRef] [PubMed]
Radiophys. Quantum Electron.
- V. M. Gelikonov, G. V. Gelikonov, and F. I. Feldchtein, "Two-wavelength optical coherence tomography," Radiophys. Quantum Electron. 47, 848-859 (2004). [CrossRef]
Science
- D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991). [CrossRef] [PubMed]
2007, Wang, Appl. Opt.
- T. Støren, A. Røyset, L. O. Svaasand, and T. Lindmo, "Measurement of dye diffusion in scattering tissue phantoms using dual-wavelength low-coherence interferometry," J. Biomed. Opt. 11, 014017 (2006). [CrossRef] [PubMed]
- C. Yang, "Molecular contrast optical coherence tomography: a review," Photochem. Photobiol. 81, 215-237 (2005). [CrossRef]
- W. Drexler, "Ultrahigh-resolution optical coherence tomography," J. Biomed. Opt. 9, 47-74 (2004). [CrossRef] [PubMed]
- A. Unterhuber, B. Povazay, K. Bizheva, B. Hermann, H. Sattmann, A. Stingl, T. Le, M. Seefeld, R. Menzel, M. Preusser, H. Budka, C. Schubert, H. Reitsamer, P. K. Ahnelt, J. E. Morgan, A. Cowey, and W. Drexler, "Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomogram phy," Phys. Med. Biol. 49, 1235-1246 (2004). [CrossRef] [PubMed]
- V. M. Gelikonov, G. V. Gelikonov, and F. I. Feldchtein, "Two-wavelength optical coherence tomography," Radiophys. Quantum Electron. 47, 848-859 (2004). [CrossRef]
- M. Pircher, E. Götzinger, R. Leitgeb, A. F. Fercher, and C. K. Hitzenberger, "Speckle reduction in optical coherence tomography by frequency compounding," J. Biomed. Opt. 8, 565-569 (2003). [CrossRef] [PubMed]
- K. Bizheva, B. Povazay, B. Hermann, H. Sattmann, W. Drexler, M. Mei, R. Holzwarth, T. Hoelzenbein, V. Wacheck, and H. Pehamberger, "Compact, broad-bandwidth fiber laser for sub-2-microm axial resolution optical coherence tomography in the 1300-nm wavelength region," Opt. Lett. 28, 707-709 (2003). [CrossRef] [PubMed]
- J. G. Fujimoto, "Optical coherence tomography for ultrahigh resolution in vivo imaging," Nat. Biotechnol. 21, 1361-1367 (2003). [CrossRef] [PubMed]
- D. Stifter, P. Burgholzer, O. Hoglinger, E. Götzinger, and C. K. Hitzenberger, "Polarisation-sensitive optical coherence tomography for material characterisation and strain-field mapping," Appl. Phys. A 76, 947-951 (2003). [CrossRef]
- Y. Pan and D. L. Farkas, "Noninvasive imaging of living human skin with dual-wavelength optical coherence tomography in two and three dimensions," J. Biomed. Opt. 3, 446-455 (1998). [CrossRef]
- J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, "Micrometer-scale resolution imaging of the anterior eye in vivo with optical coherence tomography," Arch. Ophthalmol. 112, 1584-1589 (1994). [CrossRef] [PubMed]
- J. M. Schmitt, A. Knüttel, M. Yadlowsky, and M. A. Eckhaus, "Optical-coherence tomography of a dense tissue: statistics of attenuation and backscattering," Phys. Med. Biol. 39, 1705-1720 (1994). [CrossRef] [PubMed]
- D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991). [CrossRef] [PubMed]
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